1.0 2016-09-30 22:33:31 UTC 2020-06-04 19:34:59 UTC BMDB0000608 BMDB00608 Cobalt Cobalt, also known as co(ii) or cobalt(2+) ion, belongs to the class of inorganic compounds known as homogeneous transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom. Cobalt exists as a solid, possibly soluble (in water), and possibly neutral molecule. Cobalt exists in all living organisms, ranging from bacteria to humans. Cobalt is a potentially toxic compound. Co(II) CO2+ Co(2+) COBALT (II) ion Cobalt(2+) ion Cobalt(II) cation Cobaltous ion Cobalt(2+) Aquacat Co Cobalt-59 Cobatope-57 Kobalt Super cobalt Co 58.9332 58.933200194 lambda2-cobalt(2+) ion lambda2-cobalt(2+) ion 22541-53-3 [Co++] InChI=1S/Co/q+2 XLJKHNWPARRRJB-UHFFFAOYSA-N belongs to the class of inorganic compounds known as homogeneous transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom. Inorganic compounds Homogeneous metal compounds Homogeneous transition metal compounds Homogeneous transition metal compounds Homogeneous transition metal a cation cobalt cation divalent metal cation monoatomic dication Solid melting_point 1495 °C logp 0.23 ChemAxon pka_strongest_acidic 3.09 ChemAxon iupac lambda2-cobalt(2+) ion ChemAxon average_mass 58.9332 ChemAxon mono_mass 58.933200194 ChemAxon smiles [Co++] ChemAxon formula Co ChemAxon inchi InChI=1S/Co/q+2 ChemAxon inchikey XLJKHNWPARRRJB-UHFFFAOYSA-N ChemAxon polar_surface_area 0 ChemAxon refractivity 0 ChemAxon polarizability 1.78 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 0 ChemAxon donor_count 0 ChemAxon physiological_charge 2 ChemAxon formal_charge 2 ChemAxon number_of_rings 0 ChemAxon bioavailability 1 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon Specdb::MsMs 100968 Specdb::MsMs 100969 Specdb::MsMs 100970 Specdb::MsMs 166446 Specdb::MsMs 166447 Specdb::MsMs 166448 Epidermis Wishart DS, Feunang YD, Marcu A, Guo AC, Liang K, Vazquez-Fresno R, Sajed T, Johnson D, Li C, Karu N, Sayeeda Z, Lo E, Assempour N, Berjanskii M, Singhal S, Arndt D, Liang Y, Badran H, Grant J, Serra-Cayuela A, Liu Y, Mandal R, Neveu V, Pon A, Knox C, Wilson M, Manach C, Scalbert A: HMDB 4.0: the human metabolome database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D608-D617. doi: 10.1093/nar/gkx1089. 29140435 Kidney Wishart DS, Feunang YD, Marcu A, Guo AC, Liang K, Vazquez-Fresno R, Sajed T, Johnson D, Li C, Karu N, Sayeeda Z, Lo E, Assempour N, Berjanskii M, Singhal S, Arndt D, Liang Y, Badran H, Grant J, Serra-Cayuela A, Liu Y, Mandal R, Neveu V, Pon A, Knox C, Wilson M, Manach C, Scalbert A: HMDB 4.0: the human metabolome database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D608-D617. doi: 10.1093/nar/gkx1089. 29140435 Liver 0.8 +/- 0.2 nmol/g of tissue By ICP-MS Aidin Foroutan, Carolyn Fitzsimmons, Rupasri Mandal, Hamed Piri‐Moghadam, Jiamin Zheng, AnChi Guo, Carin Li, Le Luo Guan and David S. Wishart. The Bovine Metabolome. Metabolites 2020, 10, 233; doi:10.3390/metabo10060233 Longissimus Thoracis Muscle 0.02 +/- 0.01 nmol/g of tissue By ICP-MS Aidin Foroutan, Carolyn Fitzsimmons, Rupasri Mandal, Hamed Piri‐Moghadam, Jiamin Zheng, AnChi Guo, Carin Li, Le Luo Guan and David S. Wishart. The Bovine Metabolome. Metabolites 2020, 10, 233; doi:10.3390/metabo10060233 Milk 0.04 - 0.08 uM Z. Dobrzañski et al. The Content of Microelements and Trace Elements in Raw Milk from Cows in the Silesian Region. Polish Journal of Environmental Studies Vol. 14, No 5 (2005), 685-689 Milk 0.02 +/- 0.01 uM 1% milk by ICP-MS Foroutan A, Guo AC, Vazquez-Fresno R, Lipfert M, Zhang L, Zheng J, Badran H, Budinski Z, Mandal R, Ametaj BN, Wishart DS: Chemical Composition of Commercial Cow's Milk. J Agric Food Chem. 2019 Apr 17. doi: 10.1021/acs.jafc.9b00204. 30994344 Milk 0.02 +/- 0.01 uM 2% milk by ICP-MS Foroutan A, Guo AC, Vazquez-Fresno R, Lipfert M, Zhang L, Zheng J, Badran H, Budinski Z, Mandal R, Ametaj BN, Wishart DS: Chemical Composition of Commercial Cow's Milk. J Agric Food Chem. 2019 Apr 17. doi: 10.1021/acs.jafc.9b00204. 30994344 Milk 0.03 +/- 0.01 uM 3.25% milk by ICP-MS Foroutan A, Guo AC, Vazquez-Fresno R, Lipfert M, Zhang L, Zheng J, Badran H, Budinski Z, Mandal R, Ametaj BN, Wishart DS: Chemical Composition of Commercial Cow's Milk. J Agric Food Chem. 2019 Apr 17. doi: 10.1021/acs.jafc.9b00204. 30994344 Milk 0.03 +/- 0.01 uM Skim milk by ICP-MS Foroutan A, Guo AC, Vazquez-Fresno R, Lipfert M, Zhang L, Zheng J, Badran H, Budinski Z, Mandal R, Ametaj BN, Wishart DS: Chemical Composition of Commercial Cow's Milk. J Agric Food Chem. 2019 Apr 17. doi: 10.1021/acs.jafc.9b00204. 30994344 Milk 0.0197 +/- 0.000679 uM full cream, 3.8% milk by ICP-MS. Samples were sonicated inside an ultrasound water bath for 10 min. Patricia Cava-Montesinos, M. Luisa Cervera Agustín Pastor Miguel de la Guardia. 2005. Room temperature acid sonication ICP-MS multielemental analysis of milk.Analytica Chimica Acta Volume 531, Issue 1, Pages 111-123 Milk 0.0390 +/- 0.00170 uM Skim milk by ICP-MS. Samples were sonicated inside an ultrasound water bath for 10 min. Patricia Cava-Montesinos, M. Luisa Cervera Agustín Pastor Miguel de la Guardia. 2005. Room temperature acid sonication ICP-MS multielemental analysis of milk.Analytica Chimica Acta Volume 531, Issue 1, Pages 111-123 Milk 0.0210 +/- 0.000509 uM full cream, 3.8% milk by ICP-MS. Samples were analyzed after a microwave-assisted digestion Patricia Cava-Montesinos, M. Luisa Cervera Agustín Pastor Miguel de la Guardia. 2005. Room temperature acid sonication ICP-MS multielemental analysis of milk.Analytica Chimica Acta Volume 531, Issue 1, Pages 111-123 Milk 0.0373 +/- 0.00339 uM Skim milk by ICP-MS. Samples were analyzed after a microwave-assisted digestion Patricia Cava-Montesinos, M. Luisa Cervera Agustín Pastor Miguel de la Guardia. 2005. Room temperature acid sonication ICP-MS multielemental analysis of milk.Analytica Chimica Acta Volume 531, Issue 1, Pages 111-123 Milk 0.0176 +/- 0.00136 uM full cream, 3.8% milk by ICP-MS Patricia Cava-Montesinos, M. Luisa Cervera Agustín Pastor Miguel de la Guardia. 2005. Room temperature acid sonication ICP-MS multielemental analysis of milk.Analytica Chimica Acta Volume 531, Issue 1, Pages 111-123 Milk 0.0209 +/- 0.000679 uM Skim milk by ICP-MS Patricia Cava-Montesinos, M. Luisa Cervera Agustín Pastor Miguel de la Guardia. 2005. Room temperature acid sonication ICP-MS multielemental analysis of milk.Analytica Chimica Acta Volume 531, Issue 1, Pages 111-123 Milk 0.0876 - 0.142 uM Z. Dobrzański, R. Kołacz, H. Górecka, K. Chojnacka, A. Bartkowiak. 2005. The Content of Microelements and Trace Elements in Raw Milk from Cows in the Silesian Region. Pol. J. Environ. Stud. 14(5):685–689 Ruminal Fluid 1 +/- 0.2 uM By ICP-MS Aidin Foroutan, Carolyn Fitzsimmons, Rupasri Mandal, Hamed Piri‐Moghadam, Jiamin Zheng, AnChi Guo, Carin Li, Le Luo Guan and David S. Wishart. The Bovine Metabolome. Metabolites 2020, 10, 233; doi:10.3390/metabo10060233 Semimembranosus Muscle 0.022 +/- 0.003 nmol/g of tissue By ICP-MS Aidin Foroutan, Carolyn Fitzsimmons, Rupasri Mandal, Hamed Piri‐Moghadam, Jiamin Zheng, AnChi Guo, Carin Li, Le Luo Guan and David S. Wishart. The Bovine Metabolome. Metabolites 2020, 10, 233; doi:10.3390/metabo10060233 Testis 0.05 +/- 0.01 nmol/g of tissue By ICP-MS Aidin Foroutan, Carolyn Fitzsimmons, Rupasri Mandal, Hamed Piri‐Moghadam, Jiamin Zheng, AnChi Guo, Carin Li, Le Luo Guan and David S. Wishart. The Bovine Metabolome. Metabolites 2020, 10, 233; doi:10.3390/metabo10060233 94546 FDB003581 C00175 104729 48828 Cobalt Z. Dobrzañski et al. The Content of Microelements and Trace Elements in Raw Milk from Cows in the Silesian Region. Polish Journal of Environmental Studies Vol. 14, No 5 (2005), 685-689 A. Foroutan et al. The Chemical Composition of Commercial Cow's Milk (in preparation) Patricia Cava-Montesinos, M. Luisa Cervera Agustín Pastor Miguel de la Guardia. 2005. Room temperature acid sonication ICP-MS multielemental analysis of milk.Analytica Chimica Acta Volume 531, Issue 1, Pages 111-123 Z. Dobrzański, R. Kołacz, H. Górecka, K. Chojnacka, A. Bartkowiak. 2005. The Content of Microelements and Trace Elements in Raw Milk from Cows in the Silesian Region. Pol. J. Environ. Stud. 14(5):685–689 BMDBP00174 S-adenosylmethionine synthase A7E3T7 MAT2A Enzyme BMDBP00177 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 A1A4K5 ENPP2 Enzyme BMDBP00387 Triokinase/FMN cyclase Q58DK4 TKFC Enzyme BMDBP00403 S-adenosylmethionine synthase isoform type-1 Q2KJC6 MAT1A Enzyme BMDBP00414 Methionine synthase Q4JIJ3 MTR Enzyme BMDBP00434 cGMP-specific 3',5'-cyclic phosphodiesterase Q28156 PDE5A Enzyme BMDBP00444 U8 snoRNA-decapping enzyme A1A4Q9 NUDT16 Enzyme BMDBP00477 Bis(5'-adenosyl)-triphosphatase Q1KZG4 FHIT Enzyme BMDBP00623 Methylmalonyl-CoA mutase, mitochondrial Q9GK13 MMUT Enzyme BMDBP00794 Methionine aminopeptidase Q862K9 Enzyme BMDBP00795 Methionine aminopeptidase 1 A6QLA4 METAP1 Enzyme BMDBP00796 Methionine aminopeptidase Q2HJ25 METAP1D Enzyme BMDBP00797 Methionine aminopeptidase 2 Q3ZC89 METAP2 Enzyme BMDBP01592 LYR motif-containing protein 4 Q0VCG0 LYRM4 Enzyme BMDBP01982 Transcobalamin-2 Q9XSC9 TCN2 Enzyme BMDBP01983 Methylmalonic aciduria and homocystinuria type C protein homolog Q5E9C8 MMACHC Enzyme BMDBP01984 Probable lysosomal cobalamin transporter Q3SYY9 LMBRD1 Enzyme