1.0 2016-09-30 22:47:38 UTC 2020-06-04 19:04:46 UTC BMDB0001555 BMDB01555 Pyridoxamine 5'-phosphate Pyridoxamine 5'-phosphate, also known as pyridoxamine phosphoric acid or pyridoxamine-p, belongs to the class of organic compounds known as pyridoxamine 5'-phosphates. These are heterocyclic aromatic compounds containing a pyridoxamine that carries a phosphate group at the 5'-position. Pyridoxamine 5'-phosphate is possibly soluble (in water) and a very strong basic compound (based on its pKa). Pyridoxamine 5'-phosphate exists in all living species, ranging from bacteria to humans. Pyridoxamine 5'-phosphate participates in a number of enzymatic reactions, within cattle. In particular, Pyridoxamine 5'-phosphate can be biosynthesized from pyridoxamine; which is catalyzed by the enzyme pyridoxal kinase. In addition, Pyridoxamine 5'-phosphate can be converted into pyridoxal 5'-phosphate through the action of the enzyme pyridoxine-5'-phosphate oxidase. In cattle, pyridoxamine 5'-phosphate is involved in the metabolic pathway called the vitamin B6 metabolism pathway. 4'-Deoxy-4'-aminopyridoxal-5'-phosphate Pyridoxamine 5'-(dihydrogen phosphate) Pyridoxamine 5'-phosphoric acid Pyridoxamine 5-phosphate Pyridoxamine 5-phosphoric acid Pyridoxamine phosphate 4'-Deoxy-4'-aminopyridoxal-5'-phosphoric acid Pyridoxamine 5'-(dihydrogen phosphoric acid) Pyridoxamine phosphoric acid Pyridoxamine-P PMP Pyridoxamine 5'-phosphate Pyridoxamine 5’-phosphate 4’-Deoxy-4’-aminopyridoxal-5’-phosphate 4’-Deoxy-4’-aminopyridoxal-5’-phosphoric acid C8H13N2O5P 248.173 248.056208048 {[4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl]methoxy}phosphonic acid pyridoxamine-5'-phosphate 529-96-4 CC1=NC=C(COP(O)(O)=O)C(CN)=C1O InChI=1S/C8H13N2O5P/c1-5-8(11)7(2-9)6(3-10-5)4-15-16(12,13)14/h3,11H,2,4,9H2,1H3,(H2,12,13,14) ZMJGSOSNSPKHNH-UHFFFAOYSA-N belongs to the class of organic compounds known as pyridoxamine 5'-phosphates. These are heterocyclic aromatic compounds containing a pyridoxamine that carries a phosphate group at the 5'-position. Organic compounds Organoheterocyclic compounds Pyridines and derivatives Pyridoxamines Pyridoxamine 5'-phosphates Aralkylamines Azacyclic compounds Heteroaromatic compounds Hydrocarbon derivatives Hydroxypyridines Methylpyridines Monoalkyl phosphates Monoalkylamines Organic oxides Organooxygen compounds Organopnictogen compounds Alkyl phosphate Amine Aralkylamine Aromatic heteromonocyclic compound Azacycle Heteroaromatic compound Hydrocarbon derivative Hydroxypyridine Methylpyridine Monoalkyl phosphate Organic nitrogen compound Organic oxide Organic oxygen compound Organic phosphoric acid derivative Organonitrogen compound Organooxygen compound Organopnictogen compound Phosphoric acid ester Primary aliphatic amine Primary amine Pyridoxamine 5'-phosphate Aromatic heteromonocyclic compounds aminoalkylpyridine methylpyridines monohydroxypyridine vitamin B6 phosphate Solid logp -0.99 ALOGPS logs -1.57 ALOGPS logp -2.2 ChemAxon pka_strongest_acidic 1.74 ChemAxon pka_strongest_basic 9.91 ChemAxon iupac {[4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl]methoxy}phosphonic acid ChemAxon average_mass 248.173 ChemAxon mono_mass 248.056208048 ChemAxon smiles CC1=NC=C(COP(O)(O)=O)C(CN)=C1O ChemAxon formula C8H13N2O5P ChemAxon inchi InChI=1S/C8H13N2O5P/c1-5-8(11)7(2-9)6(3-10-5)4-15-16(12,13)14/h3,11H,2,4,9H2,1H3,(H2,12,13,14) ChemAxon inchikey ZMJGSOSNSPKHNH-UHFFFAOYSA-N ChemAxon polar_surface_area 125.9 ChemAxon refractivity 56.64 ChemAxon polarizability 22.15 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 6 ChemAxon donor_count 4 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon number_of_rings 1 ChemAxon bioavailability 1 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon Vitamin B6 Metabolism SMP0087240 Specdb::CMs 2381 Specdb::CMs 38125 Specdb::CMs 172998 Specdb::MsMs 28835 Specdb::MsMs 28836 Specdb::MsMs 28837 Specdb::MsMs 35393 Specdb::MsMs 35394 Specdb::MsMs 35395 Specdb::MsMs 438369 Specdb::MsMs 438370 Specdb::MsMs 438371 Specdb::MsMs 438372 Specdb::MsMs 438373 Specdb::MsMs 446867 Specdb::MsMs 446868 Specdb::MsMs 446869 Specdb::MsMs 446870 Specdb::MsMs 446871 Specdb::MsMs 447263 Specdb::MsMs 2809289 Specdb::MsMs 2809290 Specdb::MsMs 2809291 Specdb::MsMs 2898999 Specdb::MsMs 2899000 Specdb::MsMs 2899001 Specdb::NmrOneD 4884 Specdb::NmrOneD 4885 Specdb::NmrOneD 96438 Specdb::NmrOneD 96439 Specdb::NmrOneD 96440 Specdb::NmrOneD 96441 Specdb::NmrOneD 96442 Specdb::NmrOneD 96443 Specdb::NmrOneD 96444 Specdb::NmrOneD 96445 Specdb::NmrOneD 96446 Specdb::NmrOneD 96447 Specdb::NmrOneD 96448 Specdb::NmrOneD 96449 Specdb::NmrOneD 96450 Specdb::NmrOneD 96451 Specdb::NmrOneD 96452 Specdb::NmrOneD 96453 Specdb::NmrOneD 96454 Specdb::NmrOneD 96455 Specdb::NmrOneD 96456 Specdb::NmrOneD 96457 Milk 0.191 +/- 0.178 uM Raw milk from Holstein cows Coburn SP, Mahuren JD, Pauly TA, Ericson KL, Townsend DW: Alkaline phosphatase activity and pyridoxal phosphate concentrations in the milk of various species. J Nutr. 1992 Dec;122(12):2348-53. doi: 10.1093/jn/122.12.2348. 1453218 FDB021821 1024 C00647 1053 DB02142 18335 PYRIDOXAMINE-5P C00007506 35609 Katsunishi, Masatoshi; Kondo, Osamu. Pyridoxamine-5'-phosphate. Jpn. Tokkyo Koho (1972), 2 pp. Coburn SP, Mahuren JD, Pauly TA, Ericson KL, Townsend DW: Alkaline phosphatase activity and pyridoxal phosphate concentrations in the milk of various species. J Nutr. 1992 Dec;122(12):2348-53. doi: 10.1093/jn/122.12.2348. 1453218 BMDBP00214 Pyridoxine-5'-phosphate oxidase Q5E9K3 PNPO Enzyme BMDBP01200 Pyridoxal kinase Q0II59 PDXK Enzyme