1.0 2016-09-30 22:54:00 UTC 2020-05-21 16:28:39 UTC BMDB0002314 BMDB02314 11,12-DiHETrE (+/-)11,12-dihetre (5Z,8Z,14Z)-11,12-Dihydroxyeicosa-5,8,14-trienoic acid (5Z,8Z,14Z)-11,12-Dihydroxyicosa-5,8,14-trienoic acid 11,12-DHET 11,12-Dihydroxy-5Z,8Z,14Z-eicosatrienoic acid 11,12-Dihydroxyeicosatrienoic acid (5Z,8Z,14Z)-11,12-Dihydroxyeicosa-5,8,14-trienoate (5Z,8Z,14Z)-11,12-Dihydroxyicosa-5,8,14-trienoate 11,12-Dihydroxy-5Z,8Z,14Z-eicosatrienoate 11,12-Dihydroxyeicosatrienoate (+/-)-11,12-dihydroxy-5Z,8Z,14Z,17Z-eicosatetraenoate (+/-)-11,12-dihydroxy-5Z,8Z,14Z,17Z-eicosatetraenoic acid 12-Dihydroxyicosa-5,8,14-trienoate 12-Dihydroxyicosa-5,8,14-trienoic acid 11,12-DiHETE C20H34O4 338.4816 338.245709576 (5Z,8Z,14Z)-11,12-dihydroxyicosa-5,8,14-trienoic acid 11,12-DiHETrE 192461-95-3 CCCCC\C=C/CC(O)C(O)C\C=C/C\C=C/CCCC(O)=O InChI=1S/C20H34O4/c1-2-3-4-5-9-12-15-18(21)19(22)16-13-10-7-6-8-11-14-17-20(23)24/h6,8-10,12-13,18-19,21-22H,2-5,7,11,14-17H2,1H3,(H,23,24)/b8-6-,12-9-,13-10- LRPPQRCHCPFBPE-KROJNAHFSA-N belongs to the class of organic compounds known as hydroxyeicosatrienoic acids. These are eicosanoic acids with an attached hydroxyl group and three CC double bonds. Organic compounds Lipids and lipid-like molecules Fatty Acyls Eicosanoids Hydroxyeicosatrienoic acids 1,2-diols Carbonyl compounds Carboxylic acids Hydrocarbon derivatives Hydroxy fatty acids Long-chain fatty acids Monocarboxylic acids and derivatives Organic oxides Secondary alcohols Unsaturated fatty acids 1,2-diol Alcohol Aliphatic acyclic compound Carbonyl group Carboxylic acid Carboxylic acid derivative Fatty acid Hydrocarbon derivative Hydroxy fatty acid Hydroxyeicosatrienoic acid Long-chain fatty acid Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organooxygen compound Secondary alcohol Unsaturated fatty acid Aliphatic acyclic compounds DHET Hydroxy/hydroperoxyeicosatrienoic acids Hydroxy/hydroperoxyeicosatrienoic acids Solid logp 5.41 ALOGPS logs -4.41 ALOGPS logp 4.49 ChemAxon pka_strongest_acidic 4.82 ChemAxon pka_strongest_basic -3.2 ChemAxon iupac (5Z,8Z,14Z)-11,12-dihydroxyicosa-5,8,14-trienoic acid ChemAxon average_mass 338.4816 ChemAxon mono_mass 338.245709576 ChemAxon smiles CCCCC\C=C/CC(O)C(O)C\C=C/C\C=C/CCCC(O)=O ChemAxon formula C20H34O4 ChemAxon inchi InChI=1S/C20H34O4/c1-2-3-4-5-9-12-15-18(21)19(22)16-13-10-7-6-8-11-14-17-20(23)24/h6,8-10,12-13,18-19,21-22H,2-5,7,11,14-17H2,1H3,(H,23,24)/b8-6-,12-9-,13-10- ChemAxon inchikey LRPPQRCHCPFBPE-KROJNAHFSA-N ChemAxon polar_surface_area 77.76 ChemAxon refractivity 101.87 ChemAxon polarizability 39.73 ChemAxon rotatable_bond_count 15 ChemAxon acceptor_count 4 ChemAxon donor_count 3 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon number_of_rings 0 ChemAxon bioavailability 1 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon Arachidonic Acid Metabolism SMP0087220 Specdb::MsMs 288439 Specdb::MsMs 288440 Specdb::MsMs 288441 Specdb::MsMs 327559 Specdb::MsMs 327560 Specdb::MsMs 327561 Specdb::MsMs 3054695 Specdb::MsMs 3054696 Specdb::MsMs 3054697 Specdb::MsMs 3115977 Specdb::MsMs 3115978 Specdb::MsMs 3115979 Specdb::CMs 10163 Specdb::CMs 38363 Specdb::CMs 149573 FDB022961 C14774 4446270 5283146 63969 BMDBP02908 Epoxide hydrolase 2, cytoplasmic Q17QK4 EPHX2 Enzyme