1.0 2016-09-30 23:09:53 UTC 2020-06-04 20:40:31 UTC BMDB0004628 BMDB04628 Lead Lead, also known as lead, ion (PB2+) or lead (ii) ion, belongs to the class of inorganic compounds known as homogeneous post-transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a post-transition metal atom. Lead exists as a solid, possibly soluble (in water), and possibly neutral molecule. Lead is formally rated as a possible carcinogen (by IARC 2B) and is also a potentially toxic compound. LEAD (II) ion Lead, ion (PB2+) Pb PB(2+) PB2+ Glover haro Mix MH-204 Lead ion (PB2+) Lead(2+) ion Omaha Plumbum Methyl 2-bromo-6-(((2-(5,6-dihydro-1,4,2-dioxazin-3-yl)-2-((4-(4-nitrophenyl)-1,3-thiazol-2-yl)amino)ethyl)sulfanyl)-methyl)-5-hydroxy-3-methoxybenzoate 82PB Blei Plomb Plomo Pb 207.2 207.97663585 λ²-lead(2+) ion λ²-lead(2+) ion 7439-92-1 [Pb++] InChI=1S/Pb/q+2 RVPVRDXYQKGNMQ-UHFFFAOYSA-N belongs to the class of inorganic compounds known as homogeneous post-transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a post-transition metal atom. Inorganic compounds Homogeneous metal compounds Homogeneous post-transition metal compounds Homogeneous post-transition metal compounds Homogeneous post-transition metal a cation divalent metal cation lead cation monoatomic dication Solid melting_point 327.5 °C logp 0.03 ChemAxon iupac λ²-lead(2+) ion ChemAxon average_mass 207.2 ChemAxon mono_mass 207.97663585 ChemAxon smiles [Pb++] ChemAxon formula Pb ChemAxon inchi InChI=1S/Pb/q+2 ChemAxon inchikey RVPVRDXYQKGNMQ-UHFFFAOYSA-N ChemAxon polar_surface_area 0 ChemAxon refractivity 0 ChemAxon polarizability 1.78 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 0 ChemAxon donor_count 0 ChemAxon physiological_charge 2 ChemAxon formal_charge 2 ChemAxon number_of_rings 0 ChemAxon bioavailability 1 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon Specdb::MsMs 44124 Specdb::MsMs 44125 Specdb::MsMs 44126 Specdb::MsMs 120093 Specdb::MsMs 120094 Specdb::MsMs 120095 Liver 0.019 +/- 0.003 nmol/g of tissue By ICP-MS Aidin Foroutan, Carolyn Fitzsimmons, Rupasri Mandal, Hamed Piri‐Moghadam, Jiamin Zheng, AnChi Guo, Carin Li, Le Luo Guan and David S. Wishart. The Bovine Metabolome. Metabolites 2020, 10, 233; doi:10.3390/metabo10060233 Milk 0.0203 +/- 0.000965 uM full cream, 3.8% milk by ICP-MS. Samples were sonicated inside an ultrasound water bath for 10 min. Patricia Cava-Montesinos, M. Luisa Cervera Agustín Pastor Miguel de la Guardia. 2005. Room temperature acid sonication ICP-MS multielemental analysis of milk.Analytica Chimica Acta Volume 531, Issue 1, Pages 111-123 Milk 0.00623 +/- 0.000338 uM Skim milk by ICP-MS. Samples were sonicated inside an ultrasound water bath for 10 min. Patricia Cava-Montesinos, M. Luisa Cervera Agustín Pastor Miguel de la Guardia. 2005. Room temperature acid sonication ICP-MS multielemental analysis of milk.Analytica Chimica Acta Volume 531, Issue 1, Pages 111-123 Milk 0.0203 +/- 0.000483 uM full cream, 3.8% milk by ICP-MS. Samples were analyzed after a microwave-assisted digestion Patricia Cava-Montesinos, M. Luisa Cervera Agustín Pastor Miguel de la Guardia. 2005. Room temperature acid sonication ICP-MS multielemental analysis of milk.Analytica Chimica Acta Volume 531, Issue 1, Pages 111-123 Milk 0.0111 +/- 0.000965 uM Skim milk by ICP-MS. Samples were analyzed after a microwave-assisted digestion Patricia Cava-Montesinos, M. Luisa Cervera Agustín Pastor Miguel de la Guardia. 2005. Room temperature acid sonication ICP-MS multielemental analysis of milk.Analytica Chimica Acta Volume 531, Issue 1, Pages 111-123 Milk 0.00820 +/- 0.000965 uM full cream, 3.8% milk by ICP-MS Patricia Cava-Montesinos, M. Luisa Cervera Agustín Pastor Miguel de la Guardia. 2005. Room temperature acid sonication ICP-MS multielemental analysis of milk.Analytica Chimica Acta Volume 531, Issue 1, Pages 111-123 Milk 0.0106 +/- 0.00145 uM Skim milk by ICP-MS Patricia Cava-Montesinos, M. Luisa Cervera Agustín Pastor Miguel de la Guardia. 2005. Room temperature acid sonication ICP-MS multielemental analysis of milk.Analytica Chimica Acta Volume 531, Issue 1, Pages 111-123 Milk 0.03 - 0.7 uM G.K. Murthy, U. Rhea, J.T.Peeler. Rubidium and Lead Content of Market Milk. Journal of Dairy Science. 50(5), May 1967, p. 651-654 Milk 0.0338 - 0.444 uM Najarnezhad V, Jalilzadeh-Amin G, Anassori E, Zeinali V: Lead and cadmium in raw buffalo, cow and ewe milk from west Azerbaijan, Iran. Food Addit Contam Part B Surveill. 2015;8(2):123-7. doi: 10.1080/19393210.2015.1007396. Epub 2015 Mar 25. 25588978 Milk 0.00869 uM Whole milk Ostapczuk P, Valenta P, Rutzel H, Nurnberg HW: Application of differential pulse anodic stripping voltammetry to the determination of heavy metals in environmental samples. Sci Total Environ. 1987 Feb;60:1-16. 3563481 Milk 0.00265 - 0.0903 uM Sola-Larrañaga C., Navarro-Blasco I. 2009. Chemometric analysis of minerals and trace elements in raw cow milk from the community of Navarra, Spain. Volume 112, Issue 1, Pages 189-196 Milk 0.00473 - 0.0215 uM Raw milk from Taiwan Jeng SL, Lee SJ, Lin SY: Determination of cadmium and lead in raw milk by graphite furnace atomic absorption spectrophotometer. J Dairy Sci. 1994 Apr;77(4):945-9. doi: 10.3168/jds.S0022-0302(94)77030-2. 8201052 Milk 0.00820 +/- 0.00671 uM Commercial milk Tripathi RM, Raghunath R, Sastry VN, Krishnamoorthy TM: Daily intake of heavy metals by infants through milk and milk products. Sci Total Environ. 1999 Mar 9;227(2-3):229-35. 10231985 Milk 0.020 +/- 0.001 uM 1% milk by ICP-MS Foroutan A, Guo AC, Vazquez-Fresno R, Lipfert M, Zhang L, Zheng J, Badran H, Budinski Z, Mandal R, Ametaj BN, Wishart DS: Chemical Composition of Commercial Cow's Milk. J Agric Food Chem. 2019 Apr 17. doi: 10.1021/acs.jafc.9b00204. 30994344 Milk 0.02 +/- 0.01 uM 2% milk by ICP-MS Foroutan A, Guo AC, Vazquez-Fresno R, Lipfert M, Zhang L, Zheng J, Badran H, Budinski Z, Mandal R, Ametaj BN, Wishart DS: Chemical Composition of Commercial Cow's Milk. J Agric Food Chem. 2019 Apr 17. doi: 10.1021/acs.jafc.9b00204. 30994344 Milk 0.020 +/- 0.002 uM 3.25% milk by ICP-MS Foroutan A, Guo AC, Vazquez-Fresno R, Lipfert M, Zhang L, Zheng J, Badran H, Budinski Z, Mandal R, Ametaj BN, Wishart DS: Chemical Composition of Commercial Cow's Milk. J Agric Food Chem. 2019 Apr 17. doi: 10.1021/acs.jafc.9b00204. 30994344 Milk 0.02 +/- 0.01 uM Skim milk by ICP-MS Foroutan A, Guo AC, Vazquez-Fresno R, Lipfert M, Zhang L, Zheng J, Badran H, Budinski Z, Mandal R, Ametaj BN, Wishart DS: Chemical Composition of Commercial Cow's Milk. J Agric Food Chem. 2019 Apr 17. doi: 10.1021/acs.jafc.9b00204. 30994344 Milk 0.193 - 0.772 uM Semaghiul Birghila, Simona Dobrinas, Gabriela Stanciu and Alina Soceanu. Determination of major and minor elements in milk through ICP-AES. Environmental Engineering and Management Journal. November/December 2008, Vol.7, No.6, 805-808 Testis 0.014 +/- 0.003 nmol/g of tissue By ICP-MS Aidin Foroutan, Carolyn Fitzsimmons, Rupasri Mandal, Hamed Piri‐Moghadam, Jiamin Zheng, AnChi Guo, Carin Li, Le Luo Guan and David S. Wishart. The Bovine Metabolome. Metabolites 2020, 10, 233; doi:10.3390/metabo10060233 C06696 4509317 5352425 FDB003777 Lead 25016 Ostapczuk P, Valenta P, Rutzel H, Nurnberg HW: Application of differential pulse anodic stripping voltammetry to the determination of heavy metals in environmental samples. Sci Total Environ. 1987 Feb;60:1-16. 3563481 Jeng SL, Lee SJ, Lin SY: Determination of cadmium and lead in raw milk by graphite furnace atomic absorption spectrophotometer. J Dairy Sci. 1994 Apr;77(4):945-9. doi: 10.3168/jds.S0022-0302(94)77030-2. 8201052 Tripathi RM, Raghunath R, Sastry VN, Krishnamoorthy TM: Daily intake of heavy metals by infants through milk and milk products. Sci Total Environ. 1999 Mar 9;227(2-3):229-35. 10231985 Najarnezhad V, Jalilzadeh-Amin G, Anassori E, Zeinali V: Lead and cadmium in raw buffalo, cow and ewe milk from west Azerbaijan, Iran. Food Addit Contam Part B Surveill. 2015;8(2):123-7. doi: 10.1080/19393210.2015.1007396. Epub 2015 Mar 25. 25588978 Semaghiul Birghila, Simona Dobrinas, Gabriela Stanciu and Alina Soceanu. Determination of major and minor elements in milk through ICP-AES. Environmental Engineering and Management Journal. November/December 2008, Vol.7, No.6, 805-808 G.K. Murthy, U. Rhea, J.T.Peeler. Rubidium and Lead Content of Market Milk. Journal of Dairy Science. 50(5), May 1967, p. 651-654 A. Foroutan et al. The Chemical Composition of Commercial Cow's Milk (in preparation) Patricia Cava-Montesinos, M. Luisa Cervera Agustín Pastor Miguel de la Guardia. 2005. Room temperature acid sonication ICP-MS multielemental analysis of milk.Analytica Chimica Acta Volume 531, Issue 1, Pages 111-123 Sola-Larrañaga C., Navarro-Blasco I. 2009. Chemometric analysis of minerals and trace elements in raw cow milk from the community of Navarra, Spain. Volume 112, Issue 1, Pages 189-196 BMDBP01615 TIR domain-containing adapter molecule 1 Q4JF29 TICAM1 Enzyme