1.0 2016-10-03 18:13:07 UTC 2020-05-21 16:28:22 UTC BMDB0011118 BMDB11118 Se-Adenosylselenomethionine Se-adenosylselenomethionine belongs to the class of organic compounds known as 5'-deoxyribonucleosides. These are nucleosides in which the oxygen atom at the 5'position of the ribose moiety has been replaced by another atom. The nucleobases here are limited to purine, pyrimidine, and pyridine derivatives. Se-adenosylselenomethionine is possibly soluble (in water) and a very strong basic compound (based on its pKa). Se-adenosylselenomethionine exists in all living organisms, ranging from bacteria to humans. Se-adenosylselenomethionine participates in a number of enzymatic reactions, within cattle. In particular, Se-adenosylselenomethionine can be converted into se-adenosylselenohomocysteine; which is catalyzed by the enzyme methyltransferase-like protein 6. In addition, Se-adenosylselenomethionine and phosphoric acid can be biosynthesized from selenomethionine; which is mediated by the enzyme S-adenosylmethionine synthase. In cattle, se-adenosylselenomethionine is involved in the metabolic pathway called the selenoamino acid metabolism pathway. C15H23N6O5Se 446.34 447.089514704 (3-amino-3-carboxypropyl)({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylselanium se-adenosylselenomethionine C[Se+](CCC(N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N InChI=1S/C15H22N6O5Se/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/p+1/t7?,8-,10-,11-,14-,27?/m1/s1 GGJFWMOVUFBSIN-YDBXVIPQSA-O belongs to the class of organic compounds known as 5'-deoxyribonucleosides. These are nucleosides in which the oxygen atom at the 5'position of the ribose moiety has been replaced by another atom. The nucleobases here are limited to purine, pyrimidine, and pyridine derivatives. Organic compounds Nucleosides, nucleotides, and analogues 5'-deoxyribonucleosides 5'-deoxyribonucleosides 1,2-diols 6-aminopurines Alpha amino acids Amino acids Aminopyrimidines and derivatives Azacyclic compounds Carbonyl compounds Carboxylic acids Glycosylamines Heteroaromatic compounds Hydrocarbon derivatives Imidolactams Monoalkylamines Monocarboxylic acids and derivatives N-substituted imidazoles Organic cations Organic oxides Organopnictogen compounds Oxacyclic compounds Pentoses Secondary alcohols Selenoethers Tetrahydrofurans 1,2-diol 5'-deoxyribonucleoside 6-aminopurine Alcohol Alpha-amino acid Alpha-amino acid or derivatives Amine Amino acid Amino acid or derivatives Aminopyrimidine Aromatic heteropolycyclic compound Azacycle Azole Carbonyl group Carboxylic acid Carboxylic acid derivative Glycosyl compound Heteroaromatic compound Hydrocarbon derivative Imidazole Imidazopyrimidine Imidolactam Monocarboxylic acid or derivatives Monosaccharide N-glycosyl compound N-substituted imidazole Organic cation Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Organoselenium compound Oxacycle Pentose monosaccharide Primary aliphatic amine Primary amine Purine Pyrimidine Secondary alcohol Selenoether Tetrahydrofuran Aromatic heteropolycyclic compounds Solid logp -1.93 ALOGPS logs -2.43 ALOGPS logp -5.1 ChemAxon pka_strongest_acidic 1.6 ChemAxon pka_strongest_basic 9.41 ChemAxon iupac (3-amino-3-carboxypropyl)({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylselanium ChemAxon average_mass 446.34 ChemAxon mono_mass 447.089514704 ChemAxon smiles C[Se+](CCC(N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N ChemAxon formula C15H23N6O5Se ChemAxon inchi InChI=1S/C15H22N6O5Se/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/p+1/t7?,8-,10-,11-,14-,27?/m1/s1 ChemAxon inchikey GGJFWMOVUFBSIN-YDBXVIPQSA-O ChemAxon polar_surface_area 182.63 ChemAxon refractivity 103.59 ChemAxon polarizability 39.61 ChemAxon rotatable_bond_count 7 ChemAxon acceptor_count 10 ChemAxon donor_count 5 ChemAxon physiological_charge 1 ChemAxon formal_charge 1 ChemAxon number_of_rings 3 ChemAxon bioavailability 1 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon Selenoamino Acid Metabolism SMP0087161 Specdb::MsMs 307999 Specdb::MsMs 308000 Specdb::MsMs 308001 Specdb::MsMs 2940755 Specdb::MsMs 2940756 Specdb::MsMs 2940757 Specdb::NmrOneD 11282 Specdb::NmrOneD 11283 Specdb::NmrOneD 11284 Specdb::NmrOneD 11285 Specdb::NmrOneD 11286 Specdb::NmrOneD 11287 Specdb::NmrOneD 11288 Specdb::NmrOneD 11289 Specdb::NmrOneD 11290 Specdb::NmrOneD 11291 Specdb::NmrOneD 11292 Specdb::NmrOneD 11293 Specdb::NmrOneD 11294 Specdb::NmrOneD 11295 Specdb::NmrOneD 11296 Specdb::NmrOneD 11297 Specdb::NmrOneD 11298 Specdb::NmrOneD 11299 Specdb::NmrOneD 11300 Specdb::NmrOneD 11301 Specdb::CMs 18904 Specdb::CMs 39551 Specdb::CMs 173202 24892761 FDB027900 BMDBP00403 S-adenosylmethionine synthase isoform type-1 Q2KJC6 MAT1A Enzyme BMDBP02842 tRNA N(3)-methylcytidine methyltransferase METTL2 Q0P5B2 METTL2 Enzyme BMDBP02843 Methionine adenosyltransferase 2 subunit beta Q29RI9 MAT2B Enzyme