1.0 2018-08-29 17:08:45 UTC 2020-06-04 19:49:41 UTC BMDB0062612 BMDB62612 DG(14:0/20:3(8Z,11Z,14Z)/0:0)[iso2] DG(14:0/20:3(8Z,11Z,14Z)/0:0), also known as DG(14:0/20:3) or diacylglycerol(14:0/20:3), belongs to the class of organic compounds known as 1,2-diacylglycerols. These are diacylglycerols containing a glycerol acylated at positions 1 and 2. Thus, DG(14:0/20:3(8Z,11Z,14Z)/0:0) is considered to be a diradylglycerol lipid molecule. DG(14:0/20:3(8Z,11Z,14Z)/0:0) is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. CDP-Ethanolamine and DG(14:0/20:3(8Z,11Z,14Z)/0:0) can be converted into cytidine monophosphate and PE(14:0/20:3(8Z,11Z,14Z)) through its interaction with the enzyme choline/ethanolaminephosphotransferase. In cattle, DG(14:0/20:3(8Z,11Z,14Z)/0:0) is involved in the metabolic pathway called phosphatidylethanolamine biosynthesis pe(14:0/20:3(8Z,11Z,14Z)) pathway. (2R)-1-Hydroxy-3-(tetradecanoyloxy)propan-2-yl (8Z,11Z,14Z)-icosa-8,11,14-trienoic acid C37H66O5 590.93 590.491025225 (2R)-1-hydroxy-3-(tetradecanoyloxy)propan-2-yl (8Z,11Z,14Z)-icosa-8,11,14-trienoate (2R)-1-hydroxy-3-(tetradecanoyloxy)propan-2-yl (8Z,11Z,14Z)-icosa-8,11,14-trienoate [H][C@@](CO)(COC(=O)CCCCCCCCCCCCC)OC(=O)CCCCCC\C=C/C\C=C/C\C=C/CCCCC InChI=1S/C37H66O5/c1-3-5-7-9-11-13-15-16-17-18-19-20-22-24-26-28-30-32-37(40)42-35(33-38)34-41-36(39)31-29-27-25-23-21-14-12-10-8-6-4-2/h11,13,16-17,19-20,35,38H,3-10,12,14-15,18,21-34H2,1-2H3/b13-11-,17-16-,20-19-/t35-/m1/s1 MIOCZRAJMXIEKP-WAWAFNTHSA-N belongs to the class of organic compounds known as 1,2-diacylglycerols. These are diacylglycerols containing a glycerol acylated at positions 1 and 2. Organic compounds Lipids and lipid-like molecules Glycerolipids Diradylglycerols 1,2-diacylglycerols Carbonyl compounds Carboxylic acid esters Dicarboxylic acids and derivatives Fatty acid esters Hydrocarbon derivatives Organic oxides Primary alcohols 1,2-acyl-sn-glycerol Alcohol Aliphatic acyclic compound Carbonyl group Carboxylic acid derivative Carboxylic acid ester Dicarboxylic acid or derivatives Fatty acid ester Fatty acyl Hydrocarbon derivative Organic oxide Organic oxygen compound Organooxygen compound Primary alcohol Aliphatic acyclic compounds logp 9.77 ALOGPS logs -7.62 ALOGPS logp 11.81 ChemAxon pka_strongest_acidic 14.58 ChemAxon pka_strongest_basic -3 ChemAxon iupac (2R)-1-hydroxy-3-(tetradecanoyloxy)propan-2-yl (8Z,11Z,14Z)-icosa-8,11,14-trienoate ChemAxon average_mass 590.93 ChemAxon mono_mass 590.491025225 ChemAxon smiles [H][C@@](CO)(COC(=O)CCCCCCCCCCCCC)OC(=O)CCCCCC\C=C/C\C=C/C\C=C/CCCCC ChemAxon formula C37H66O5 ChemAxon inchi InChI=1S/C37H66O5/c1-3-5-7-9-11-13-15-16-17-18-19-20-22-24-26-28-30-32-37(40)42-35(33-38)34-41-36(39)31-29-27-25-23-21-14-12-10-8-6-4-2/h11,13,16-17,19-20,35,38H,3-10,12,14-15,18,21-34H2,1-2H3/b13-11-,17-16-,20-19-/t35-/m1/s1 ChemAxon inchikey MIOCZRAJMXIEKP-WAWAFNTHSA-N ChemAxon polar_surface_area 72.83 ChemAxon refractivity 180.25 ChemAxon polarizability 76.53 ChemAxon rotatable_bond_count 33 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon number_of_rings 0 ChemAxon bioavailability 0 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon Milk 2.3 +/- 0.2 uM Commercial 1% milk by LC-HRMS Foroutan A, Guo AC, Vazquez-Fresno R, Lipfert M, Zhang L, Zheng J, Badran H, Budinski Z, Mandal R, Ametaj BN, Wishart DS: Chemical Composition of Commercial Cow's Milk. J Agric Food Chem. 2019 Apr 17. doi: 10.1021/acs.jafc.9b00204. 30994344 Milk 3.3 +/- 0.1 uM Commercial 2% milk by LC-HRMS Foroutan A, Guo AC, Vazquez-Fresno R, Lipfert M, Zhang L, Zheng J, Badran H, Budinski Z, Mandal R, Ametaj BN, Wishart DS: Chemical Composition of Commercial Cow's Milk. J Agric Food Chem. 2019 Apr 17. doi: 10.1021/acs.jafc.9b00204. 30994344 Milk 4.6 +/- 0.3 uM Commercial 3.25% milk by LC-HRMS Foroutan A, Guo AC, Vazquez-Fresno R, Lipfert M, Zhang L, Zheng J, Badran H, Budinski Z, Mandal R, Ametaj BN, Wishart DS: Chemical Composition of Commercial Cow's Milk. J Agric Food Chem. 2019 Apr 17. doi: 10.1021/acs.jafc.9b00204. 30994344 Milk 0.96 +/- 0.03 uM Commercial skim milk by LC-HRMS Foroutan A, Guo AC, Vazquez-Fresno R, Lipfert M, Zhang L, Zheng J, Badran H, Budinski Z, Mandal R, Ametaj BN, Wishart DS: Chemical Composition of Commercial Cow's Milk. J Agric Food Chem. 2019 Apr 17. doi: 10.1021/acs.jafc.9b00204. 30994344 A. Foroutan et al. The Chemical Composition of Commercial Cow's Milk (in preparation)