1.0 2020-03-10 17:00:47 UTC 2020-04-22 18:55:54 UTC BMDB0096075 BMDB96075 1,4-Dithiothreitol (2R,3R)-1,4-Dimercaptobutane-2,3-diol 2,3-DIHYDROXY-1,4-dithiobutane DL-Threo-1,4-dimercapto-2,3-butanediol L-Dithiothreitol L-DTT L-Threo-1,4-dimercapto-2,3-butanediol Threo-1,4-dimercapto-2,3-butanediol Dithiothreitol Sputolysin Clelands reagent Cleland reagent Cleland's reagent Reagent, cleland Reagent, cleland's C4H10O2S2 154.251 154.012220944 (2R,3R)-1,4-disulfanylbutane-2,3-diol L-dithiothreitol 3483-12-3 O[C@@H](CS)[C@@H](O)CS InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m0/s1 VHJLVAABSRFDPM-IMJSIDKUSA-N belongs to the class of organic compounds known as 1,2-diols. These are polyols containing an alcohol group at two adjacent positions. Organic compounds Organic oxygen compounds Organooxygen compounds Alcohols and polyols 1,2-diols Alkylthiols Hydrocarbon derivatives Secondary alcohols 1,2-diol Aliphatic acyclic compound Alkylthiol Hydrocarbon derivative Organosulfur compound Secondary alcohol Aliphatic acyclic compounds 1,4-dithiothreitol logp 0.18 ALOGPS logs -1.48 ALOGPS logp -0.28 ChemAxon pka_strongest_acidic 9.62 ChemAxon pka_strongest_basic -3.3 ChemAxon iupac (2R,3R)-1,4-disulfanylbutane-2,3-diol ChemAxon average_mass 154.251 ChemAxon mono_mass 154.012220944 ChemAxon smiles O[C@@H](CS)[C@@H](O)CS ChemAxon formula C4H10O2S2 ChemAxon inchi InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m0/s1 ChemAxon inchikey VHJLVAABSRFDPM-IMJSIDKUSA-N ChemAxon polar_surface_area 40.46 ChemAxon refractivity 38.84 ChemAxon polarizability 15.68 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 2 ChemAxon donor_count 4 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon number_of_rings 0 ChemAxon bioavailability 1 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon Specdb::MsIr 2910 Specdb::MsIr 2911 Specdb::MsIr 2912 Specdb::CMs 1540 Specdb::CMs 8250 Specdb::CMs 31573 Specdb::CMs 40128 Specdb::CMs 155369 Specdb::MsMs 258639 Specdb::MsMs 258640 Specdb::MsMs 258641 Specdb::MsMs 278577 Specdb::MsMs 278578 Specdb::MsMs 278579 Specdb::MsMs 2792297 Specdb::MsMs 2792298 Specdb::MsMs 2792299 Specdb::MsMs 2917406 Specdb::MsMs 2917407 Specdb::MsMs 2917408 Specdb::NmrOneD 99698 Specdb::NmrOneD 99699 Specdb::NmrOneD 99700 Specdb::NmrOneD 99701 Specdb::NmrOneD 99702 Specdb::NmrOneD 99703 Specdb::NmrOneD 99704 Specdb::NmrOneD 99705 Specdb::NmrOneD 99706 Specdb::NmrOneD 99707 Specdb::NmrOneD 99708 Specdb::NmrOneD 99709 Specdb::NmrOneD 99710 Specdb::NmrOneD 99711 Specdb::NmrOneD 99712 Specdb::NmrOneD 99713 Specdb::NmrOneD 99714 Specdb::NmrOneD 99715 Specdb::NmrOneD 99716 Specdb::NmrOneD 99717 388336 FDB029593 439196 C00265 42106 DB04447 DTT Dithiothreitol