| Identification |
|---|
| BMDB Protein ID
| BMDBP00081 |
| Secondary Accession Numbers
| None |
| Name
| Arylsulfatase A |
| Synonyms
|
Not Available
|
| Gene Name
| ARSA |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Inorganic ion transport and metabolism |
| Specific Function
| Hydrolyzes cerebroside sulfate. |
| Pathways
|
- Androgen and Estrogen Metabolism
- Sphingolipid Metabolism
|
| Reactions
|
| 3-O-Sulfogalactosylceramide (d18:1/24:0) + Water → Galactosylceramide (d18:1/16:0) + Sulfate |
details
|
| DHEA sulfate + Water → Dehydroepiandrosterone + Sulfate |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| ARSA |
| Gene Sequence
|
>1524 bp
ATGGAGGCTCTGTGGACCCTCACTCTGGCCTTGGCCGCAGGTCTGGCTGCTGCCAGCCCA
CCTAACATCCTGCTGATCTTTGCTGATGACCTGGGCTACGGGGACCTGGGCTCCTATGGG
CACCCCAGCTCCACCACTCCCAATCTGGACCAGTTGGCCGCAGGGGGTCTGCGGTTCACA
GACTTCTACGTGCCTGTGTCTCTGTGCACACCCTCCCGGGCTGCCCTCCTGACCGGCCGA
CTCCCAGTTCGGATGGGTTTGTACCCTGGAGTTCTGGAGCCCAGCTCCCGAGGGGGCCTG
CCCCTGGATGAGGTGACCTTGGCTGAGGTCCTGGCTGCCCAAGGCTACCTCACAGGGATA
GCTGGCAAGTGGCACCTTGGGGTGGGGCCTGAGGGGGCCTTTCTGCCCCCCCACCACGGC
TTCCATCGATTCCTGGGCATCCCATACTCCCATGACCAGGGCCCTTGCCAGAACCTGACC
TGCTTCCCCCCGGCCACCCCCTGCGAAGGCATCTGCGACCAGGGCCTGGTCCCTATCCCA
CTGTTGGCCAACCTGTCGGTGGAGGCACAGCCCCCTTGGCTGCCTGGACTCGAGGCTCGC
TACGTGGCCTTTGCCCGCGACCTCATGACTGACGCCCAACACCAAGGCCGCCCGTTCTTC
CTGTACTACGCCTCCCACCACACCCACTACCCCCAGTTCAGTGGGCAGAGCTTCCCAGGG
CACTCAGGCCGAGGGCCATTTGGGGACTCCCTGATGGAGCTGGACGCGGCTGTGGGGGCC
CTGATGACAGCTGTGGGGGACCTGGGGCTGCTTGGAGAGACGCTCGTCTTCTTCACTGCA
GACAACGGGCCTGAGACGATGCGGATGTCCCATGGTGGCTGCTCTGGCCTCCTGCGATGC
GGAAAAGGAACCACTTTCGAAGGGGGCGTCCGAGAGCCTGCCTTGGCCTTCTGGCCAGGT
CACATCGCTCCCGGTGTGACCCATGAGCTGGCCAGCTCCCTGGACCTGCTGCCCACCCTG
GCAGCCCTGGCGGGGGCCCAACTGCCCAATATCACCTTGGATGGCGTTGACCTCAGCCCC
CTGCTGTTGGGCACAGGCAAGAGCCCCCGGCACACCCTCTTCTTCTACTCGGCCTACCCG
GATGAGGTCCGAGGGGTCTTTGCAGTGCGGAGCGGGAAGTACAAGGCACACTTCTTTACC
CAGGGCTCTGTCCACAGCGACACCACTGCAGACCCTGCCTGCCACGCCTCTAATCCTCTG
ACTGCCCATGAGCCCCCGCTGCTCTTTGACCTGTCTGAGGACCCTGGTGAGAACTACAAC
CTTCTGGACAGTGTGGATGAGGTTGCCCCAGAGGCGCTGCAGGCAGTGAAGCAACTTGAG
CTGCTCAAGGCCCAGTTTGATGCTGCCATGACCTTCGGACCCAGCCAGATGGCGCAGGGT
GAGGACCCCACCCTGCAGGTCTGCTGCCAGCCCAGCTGCACCCCCCGGCCGTCCTGCTGC
CACTGCCCTGAGTTCCAGCCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 507 |
| Molecular Weight
| 53807.0 |
| Theoretical pI
| 4.9 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Arylsulfatase A
MEALWTLTLALAAGLAAASPPNILLIFADDLGYGDLGSYGHPSSTTPNLDQLAAGGLRFT
DFYVPVSLCTPSRAALLTGRLPVRMGLYPGVLEPSSRGGLPLDEVTLAEVLAAQGYLTGI
AGKWHLGVGPEGAFLPPHHGFHRFLGIPYSHDQGPCQNLTCFPPATPCEGICDQGLVPIP
LLANLSVEAQPPWLPGLEARYVAFARDLMTDAQHQGRPFFLYYASHHTHYPQFSGQSFPG
HSGRGPFGDSLMELDAAVGALMTAVGDLGLLGETLVFFTADNGPETMRMSHGGCSGLLRC
GKGTTFEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAQLPNITLDGVDLSP
LLLGTGKSPRHTLFFYSAYPDEVRGVFAVRSGKYKAHFFTQGSVHSDTTADPACHASNPL
TAHEPPLLFDLSEDPGENYNLLDSVDEVAPEALQAVKQLELLKAQFDAAMTFGPSQMAQG
EDPTLQVCCQPSCTPRPSCCHCPEFQP
|
| External Links |
|---|
| GenBank ID Protein
| AAI23817.1 |
| UniProtKB/Swiss-Prot ID
| Q08DD1 |
| UniProtKB/Swiss-Prot Entry Name
| ARSA_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC123816 |
| GeneCard ID
| ARSA |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
