| Identification |
|---|
| BMDB Protein ID
| BMDBP00099 |
| Secondary Accession Numbers
| None |
| Name
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| NDUFS2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| Not Available |
| SNPs
| NDUFS2 |
| Gene Sequence
|
>1392 bp
ATGGCGGCGCTCAGGGCTCTGTGCCGCCTGCGGGGCGCCGCGGCCCAGGTGCTGCGGCCC
GGGGCTGGGGTCCGACTGCCGATTCAGCCCAGCAGGGGTGCTCGGCAGTGGCAGCCAGAT
GTGGAATGGGCAGAGCAGTACGGGGGTGCTGTCATGTACCCCACCAAGGAAACAGCCCAC
TGGAAACCTCCTCCTTGGAATGATGTGGACCCTCCAAAGGACACACTGGTGTCGAACCTG
ACCCTGAACTTTGGGCCCCAGCACCCAGCAGCCCATGGAGTCCTGCGGCTAGTGATGGAG
CTGAGTGGGGAGATGGTGCGGAAGTGCGACCCCCACATCGGGCTGCTGCACCGGGGCACT
GAGAAGCTAATTGAATACAAGACCTATCTGCAGGCCCTTCCATACTTTGACCGGCTGGAC
TATGTATCCATGATGTGTAATGAACAGGCCTACTCACTGGCCGTGGAGAAGCTGCTCAAC
ATCCAGCCTCCTCCTCGTGCACAATGGATCCGAGTGCTATTTGGAGAAATCACTCGACTT
TTGAACCACATCATGGCTGTGACCACACATGCCCTGGACATTGGGGCTATGACCCCTTTC
TTCTGGATGTTTGAAGAAAGGGAGAAGATGTTCGAGTTCTACGAGCGCGTGTCTGGGGCT
CGGATGCATGCTGCTTACGTCCGGCCAGGAGGTGTGCACCAGGACCTACCCCTTGGGCTT
ATGGATGACATTTATGAGTTTTCTAAGAACTTTTCTCTTCGGATTGACGAGCTGGAGGAG
ATGCTGACCAACAATAGGATCTGGCGAAATCGGACAGTCGACATTGGGATTGTAACAGCA
GAAGACGCACTGAACTATGGTTTTAGTGGGGTGATGCTCCGGGGCTCAGGTATCCAGTGG
GACCTGCGGAAGACCCAGCCCTACGATGTCTACGACCAGGTGGAGTTTGATGTGCCTATT
GGCTCTCGAGGGGACTGCTATGATAGATACCTGTGTCGGGTGGAGGAGATGCGCCAGTCC
ATTCGAATCATCTCACAGTGTCTGAACAAGATGCCTCCTGGGGAGATCAAGGTTGATGAT
GCCAAAGTGTCTCCACCAAAACGAGCAGAAATGAAGACGTCTATGGAGTCACTGATCCAT
CACTTTAAGCTGTACACTGAGGGCTACCAAGTTCCCCCAGGAGCCACATACACAGCCATC
GAGGCGCCCAAGGGAGAGTTTGGCGTGTACCTGGTGTCTGATGGTAGCAGCCGCCCTTAC
CGATGCAAGATCAAGGCTCCTGGTTTTGCTCACCTGGCTGGTCTGGACAAGATGTCTAAG
GGACACATGTTGGCGGACGTCGTTGCCATCATAGGTACCCAAGATATTGTGTTTGGAGAA
GTAGACCGGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 463 |
| Molecular Weight
| 52556.0 |
| Theoretical pI
| 6.99 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
MAALRALCRLRGAAAQVLRPGAGVRLPIQPSRGARQWQPDVEWAEQYGGAVMYPTKETAH
WKPPPWNDVDPPKDTLVSNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGT
EKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRL
LNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYVRPGGVHQDLPLGL
MDDIYEFSKNFSLRIDELEEMLTNNRIWRNRTVDIGIVTAEDALNYGFSGVMLRGSGIQW
DLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQSIRIISQCLNKMPPGEIKVDD
AKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPY
RCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR
|
| External Links |
|---|
| GenBank ID Protein
| AAI19925.1 |
| UniProtKB/Swiss-Prot ID
| P17694 |
| UniProtKB/Swiss-Prot Entry Name
| NDUS2_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC119924 |
| GeneCard ID
| NDUFS2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
