| Identification |
|---|
| BMDB Protein ID
| BMDBP00101 |
| Secondary Accession Numbers
| None |
| Name
| Diphosphomevalonate decarboxylase |
| Synonyms
|
Not Available
|
| Gene Name
| MVD |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| Performs the first committed step in the biosynthesis of isoprenes. |
| Pathways
|
- Cholesterol biosynthesis
- Steroid Biosynthesis
|
| Reactions
|
| Adenosine triphosphate + 5-Diphosphomevalonic acid → ADP + Hydrogen phosphate + Isopentenyl pyrophosphate + Carbon dioxide |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 18 |
| Locus
| Not Available |
| SNPs
| MVD |
| Gene Sequence
|
>1203 bp
ATGGCCTCAGAGAAGCCGATCGTGGTGGTGACTTGCACCGCGCCCGTCAACATCGCTGTC
GTCAAGTACTGGGGAAAGCGAGATGAGGAGCTGATCCTGCCCATCAATTCCTCTCTGAGC
GTCACATTGCACCAGGATCAGTTGAAAACCACCACGACGGCCGCCATCAGCAGGGACTTC
ACAGAGGACCGGATTTGGCTGAATGGCCGGGAGGAGGATATGGGGCACCCTCGCCTCCAG
GCCTGCCTGAGGGAGATCCGCCGCCTGGCCCGTAAGCGGAGGAGCGACGGCCATGAAGAC
CCACTGCCTCTCAGCCTCAGCTACAAGGTTCATGTGGCCTCGGAGAACAACTTCCCCACG
GCTGCAGGCCTGGCCTCCTCGGCTGCAGGCTATGCCTGCTTAGCCTACACCCTGGCCCGG
GTCTATGGGGTGGACAGCGATCTGTCGGAAGTGGCCCGCAGGGGCTCAGGCAGCGCCTGC
CGCAGCCTGTACGGTGGCTTTGTGGAGTGGCAGATGGGTGAGCGCCCTGATGGGAAGGAC
AGCGTCGCCTGTCAGGTGGCCCCCGAGTCACACTGGCCGGAGCTCCGAGTCCTGATCCTC
GTGGTGAGCGCTGAGAGGAAGCCGATGGGCAGCACGGCAGGCATGCAGACCAGCGTGGAG
ACCAGTGCCCTGCTCAAGTTCCGGGCAGAGGCACTGGTGCCGCCGCGCATGGCCGAGATG
ACCCGCTGCATCAGGGAGCGCAACTTCCAGGCCTTTGGCCAGCTGACCATGAAGGACAGC
AACCAGTTCCACGCCACCTGCCTGGACACCTTCCCGCCCATCTCCTACCTCAGTGACACA
TCCCGGCGCATCATCCAGCTGGTGCACCGCTTCAACGCTCACCATGGGCAGACCAAGGTG
GCGTACACTTTTGATGCGGGTCCCAACGCTGTGGTCTTCACTCTGGATGACACCGTGGCT
GAGTTTGTGGCTGCCGTGAGGCACAGCTTCCCCCCTGAGTCGAACGGAGACAAGTTTCTG
AAGGGGCTGCCCGTGGAGCCCGTCCTGCTCTCAGATGAGCTTAAAGCTGTGCTGGGCATG
GACCCCGTCCCTGGCAGCATCAGATACATCATTGCCACCCAGGTGGGACCCGGGCCTCAG
GTCCTGGATGACCCTGGCGCTCATCTCCTGGGTCCTGACGGTCTGCCAAAGCCAGCTGCC
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 400 |
| Molecular Weight
| 43732.0 |
| Theoretical pI
| 6.9 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Diphosphomevalonate decarboxylase
MASEKPIVVVTCTAPVNIAVVKYWGKRDEELILPINSSLSVTLHQDQLKTTTTAAISRDF
TEDRIWLNGREEDMGHPRLQACLREIRRLARKRRSDGHEDPLPLSLSYKVHVASENNFPT
AAGLASSAAGYACLAYTLARVYGVDSDLSEVARRGSGSACRSLYGGFVEWQMGERPDGKD
SVACQVAPESHWPELRVLILVVSAERKPMGSTAGMQTSVETSALLKFRAEALVPPRMAEM
TRCIRERNFQAFGQLTMKDSNQFHATCLDTFPPISYLSDTSRRIIQLVHRFNAHHGQTKV
AYTFDAGPNAVVFTLDDTVAEFVAAVRHSFPPESNGDKFLKGLPVEPVLLSDELKAVLGM
DPVPGSIRYIIATQVGPGPQVLDDPGAHLLGPDGLPKPAA
|
| External Links |
|---|
| GenBank ID Protein
| AAI20433.1 |
| UniProtKB/Swiss-Prot ID
| Q0P570 |
| UniProtKB/Swiss-Prot Entry Name
| MVD1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC120432 |
| GeneCard ID
| MVD |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
