| Identification |
|---|
| BMDB Protein ID
| BMDBP00107 |
| Secondary Accession Numbers
| None |
| Name
| Deoxyribose-phosphate aldolase |
| Synonyms
|
Not Available
|
| Gene Name
| DERA |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Nucleotide transport and metabolism |
| Specific Function
| Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation. |
| Pathways
|
- 2-deoxy-D-ribose 1-phosphate degradation
- Carbohydrate degradation
- D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2
- Pentose Phosphate Pathway
|
| Reactions
|
| D-Glyceraldehyde 3-phosphate + Acetaldehyde → Deoxyribose 5-phosphate |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| DERA |
| Gene Sequence
|
>957 bp
ATGTCGGCGCACCAGCAGGGCACGGAGCTCGACCTTAGCTGGATCTCCAAAATACAAGTG
AATAAACCAGCAGTGCTAAGACGTGCAGAACAAATCCAGGCTCGTAGACCTGTGAAAAAG
GAGTGGCAGGCTGCATGGCTCCTGAAGGCTGTTACCTGTATAGATCTTACTACACTTTCA
GGTGATGACACAGCTTCCAACATTCAAAGGCTGTGTTATAAAGCCAAGTATCCAATCCGG
GAAGACCTCTTAAAAGCTTTAAATATGCATGATAAAGGCATCACTACAGCTGCCGTTTGT
GTTTATCCTGCCCGTGTGTGTGATGCAGTGAGAGCTCTAAAGGCTGCAGGCTGTGACATC
CCAGTGGCATCAGTGGCCACTGGCTTTCCAGCTGCACAGACTCATTTGAAAACACGATTA
GAAGAGATAAGATTGGCCGTGGAAGATGGAGCTACGGAAATCGATGTGGTGATTAACAGG
ACCTTGGTGCTGACAGGCCAGTGGAAAGCCCTGTATGATGAGATTCGTCAGTTTCGCAAG
GCCTGTGGGGAGGCTCATCTCAAAACCATCTTAGCCACAGGAGAACTTGGATCTCTCACC
AACGTCTATAAAGCCAGTATGATAGCCATGATGGCAGGATCAGATTTTATTAAGACCTCT
ACGGGAAAAGAAACAGTAAATGCTACCTTTCCAGTAGCTATAGTTATGCTTCGGGCCATT
AGAGATTTCTTCTGGAAAACTGGAAACAAGGTAGGCTTTAAACCGGCCGGAGGCATCCGC
AGTGCGAAGGACTCCCTTGTGTGGCTCTCTCTCATAAAGGAGGAGCTGGGAGACGAGTGG
ATGAAGCCTGAACTCTTTCGAATAGGTGCCAGCACTCTACTTGCCGACATTGAGAGGCAG
ATTTACCATCACGTGACTGGAAGATACGCAGCCTACCATGACCTCCCCATGTCTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 318 |
| Molecular Weight
| 35246.0 |
| Theoretical pI
| 9.33 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Putative deoxyribose-phosphate aldolase
MSAHQQGTELDLSWISKIQVNKPAVLRRAEQIQARRPVKKEWQAAWLLKAVTCIDLTTLS
GDDTASNIQRLCYKAKYPIREDLLKALNMHDKGITTAAVCVYPARVCDAVRALKAAGCDI
PVASVATGFPAAQTHLKTRLEEIRLAVEDGATEIDVVINRTLVLTGQWKALYDEIRQFRK
ACGEAHLKTILATGELGSLTNVYKASMIAMMAGSDFIKTSTGKETVNATFPVAIVMLRAI
RDFFWKTGNKVGFKPAGGIRSAKDSLVWLSLIKEELGDEWMKPELFRIGASTLLADIERQ
IYHHVTGRYAAYHDLPMS
|
| External Links |
|---|
| GenBank ID Protein
| AAI02243.1 |
| UniProtKB/Swiss-Prot ID
| Q3T0V9 |
| UniProtKB/Swiss-Prot Entry Name
| DEOC_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC102242 |
| GeneCard ID
| DERA |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
