1.0 2018-05-07 22:20:54 UTC 2020-05-20 21:06:56 UTC BMDBP00118 BMDBP03054 Enzyme MTHFD1L Nucleotide transport and metabolism May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2. One-carbon metabolism Tetrahydrofolate interconversion BMDB0000142 Formic acid BMDB0000972 N10-Formyl-THF BMDB0001341 ADP BMDB0001429 Phosphate BMDB0001846 Tetrahydrofolic acid BMDB0001354 5,10-Methenyltetrahydrofolic acid BMDB0000221 NADPH BMDB0001533 5,10-Methylene-THF BMDB0000217 NADP 9 >2928 bp ATGAGCGCGCGCCTGCCGTTCGTCCTGCGCCGGCTCGCGCGCCCGCAGCACCCCGGCTCG CCGCGCCGCCTCCCATCTCTTTGTCGCGCCAGCAGCGGCAGGGGCAGCGGATGTGGCGGC GGGGAGGGTCTCCTCGGGCAACAGCGGCTGCGGGATACCCAGGCCGGGAGCAGCCGGGGC CCGGGCAGCCCGGCGCCCCCAGCTCGGGACTCGATCGTCCGAGAAGTCATTCAGAATTCG AAAGAAGTTCTGAGTTTATTGCAAGAAAAGACCCCTACCTTTAAGCCGGTTCTTGCTATT ATTCAGGCAGGTGATGATAACTTGATGCAAGAAGTAAACCAGAATTTGGCTGAGGAGGCT GGTCTGAACATCACCCACATCTGCCTTCCTGCGGAGAGCGGGGAAGATGAGATTATAGAT GAGATCCTGAAGATTAATGAAGACAGCAGAGTACATGGCCTTGCCCTTCAGATCGCTGAG ACCTCATTTAGCAACAAAATCCTCAATGCTTTGAAACCAGAAAAAGATGTGGATGGATTA ACGGATGTCAACCTGGGGAAGTTGGTCCGAGGAGATGCCCATGGGTGTTTTATTTCACCT GTGGCCAGAGCTGTAATCGAACTTCTTGAAAAGTCAGGTGTCAGCTTAGATGGAAAGAAG ATCTTGGTAATAGGAGCCCATGGGTCTTTGGAAGCCACCCTACAATGTCTGTTCCAGAGA AAAGGGTCCATGACAATGAGCTCCCAGTGGAAAACACCTCAGCTTCAAGGCAAGCTACAG GAGGCTGATATTGTGGTCTTGGGCTCACCCAAGCCAGAAGAGATCCCCCTTTCTTGGATT CAACCGGGAACTACTGTTTTCAACTGTTCGCATGACTTTCTATCAGGGAAGGCTGCATGC ATTTCTTCTGGCGTCCATGGTATTAGTCCCATCGCCGAAGATGTGAGTCTCCTTGCTGCT GCTCTGCGGATTCAGAACATGGTCAGCAGCGGAAGGAGATGGCTCCGTGAGCAGCAGCAC CGCAGATGGAGACTTCACTGCTTGAAACTTCAGCCTCTGTCCCCTGTACCAAGTGATATC GAGATTTCGAGAGCGCAGACTCCAAAAGCTGTGGAGATCCTTGCCAAGGAGATAGGATTG CTTGCAGACGAAATTGAAATCTATGGCAAAAGCAAAGCCAAAGTACGTTTGTCCTTGTTG GAAAGGTTAAAGGATCAAGCAGATGGAAAATACGTCTTGGTTGCTGGGATCACACCCACC CCTCTTGGAGAAGGAAAAAGTACAGTTACAATTGGGCTTGTACAGGCATTGACTGCGCAC CTGAACGTCAACTCCTTTGCCTGTCTCAGGCAGCCTTCTCAAGGACCAACTTTCGGAGTT AAAGGAGGAGCTGCAGGTGGTGGATATGCCCAGGTCATCCCTATGGAGGAGTTCAACCTT CACCTTACTGGGGACATCCACGCCATTACTGCTGCCAATAATTTGCTGGCTGCCGCTATC GACGCAAGGATTTTGCATGAAAACACTCAAACAGATAAGGCCCTGTATAATCGACTGGTT CCTTCAGTGAATGGTGTTCGAGAATTTTCAAAAATTCAACTTGCTCGGCTGAAAAGACTG GGAATAAATAAGACTGATCCGAGTGCGCTGACAGAAGAGGAAATGAGGAAATTTGCCCGT CTTGACATCGACCCCTCCACCATCACATGGCAGAGAGTTGTGGATACCAATGACCGATTT CTACGGAAAATAACCATTGGGCAGGCGAACACAGAGAAGGGCTGTTCCCGGCAGGCGCAG TTTGACATCGCAGTGGCCAGTGAAATCATGGCAGTGCTGGCTCTGACCGACAGCCTATCG GACATGAAGGAGCGGCTGGGAAGAATGGTGGTGGCCAGTGACAGAAATGGACAGCCTGTG ACAGCAGACGACTTGGGGGTGACAGGTGCTTTGACTGTTCTGATGAAAGACGCGATAAAA CCAAATCTGATGCAGACCCTAGAAGGGACGCCTGTATTTGTGCATGCTGGCCCCTTTGCC AACATCGCTCATGGCAACTCTTCAGTGTTGGCTGATAAAATTGCCCTGAAACTGGTTGGG GAAGGAGGATTTGTGGTGACTGAAGCTGGCTTTGGTGCTGATATTGGCATGGAGAAATTC TTCAACATCAAGTGCAGAGCTTCTGGTTTGGTGCCCAGCGTTGTGGTTCTGGTGGCGACC GTGCGGGCTCTGAAGATGCATGGAGGTGGACCGAGCGTAACTGCTGGGGTCCCTCTTAGA AAGGAATATACCGAAGAGAACCTCCAGCTGGTGGCAGATGGCTGCTGTAACCTGGAGAAG CAAATTCAGATCGCTCAGCTCTTCGGGGTCCCTGTTGTTGTGGCTCTGAATGTCTTCAAG ACCGACACCCGCGCAGAGATTGACTTGGTGTGTGAGCTTGCGAAGCGGGCCGGCGCCTTC AATGCAGTCCCCTGCTATCACTGGTCGATTGGTGGGAAAGGGTCAGTGGACCTGGCTTGG GCTGTGAGAGAAGCTGCAAGCAAAGAAAGTCGTTTCCAGTTCCTGTATGATGTGCAGCTT CCAATTGTGGAAAAGATAAGAACCATTGCCCAGTCTGTCTATGGAGCCAAAGATATTGAA CTCTCTCCAGAAGCACAATCCAAAATAGATCGTTACACGGAACAGGGATTTGGAAATTTG CCCATCTGCATGGCGAAGACCCACCTCTCCCTGTCTCACCAACCTGACAAGAAAGGCGTA CCCAAGGGTTTCATTCTACCCATTAGTGACGTCCGGGCCAGCATAGGCGCCGGATTCATT TACCCATTGGTTGGAACGATGAGCACCATGCCAGGACTGCCAACTCGGCCCTGCTTCTAC GACATAGATCTTGATACAGAAACAGAGCAGGTTAAAGGCTTGTTCTGA 975 105227.0 7.78 None >Monofunctional C1-tetrahydrofolate synthase, mitochondrial MSARLPFVLRRLARPQHPGSPRRLPSLCRASSGRGSGCGGGEGLLGQQRLRDTQAGSSRG PGSPAPPARDSIVREVIQNSKEVLSLLQEKTPTFKPVLAIIQAGDDNLMQEVNQNLAEEA GLNITHICLPAESGEDEIIDEILKINEDSRVHGLALQIAETSFSNKILNALKPEKDVDGL TDVNLGKLVRGDAHECFISPVARAVIELLEKSGVSLDGKKILVIGAHGSLEATLQCLFQR KGSMTMSSQWKTPQLQGKLQEADIVVLGSPKPEEIPLSWIQPGTTVFNCSHDFLSGKAAC ISSGVHGISPIAEDVSLLAAALRIQNMVSSGRRWLREQQHRRWRLHCLKLQPLSPVPSDI EISRAQTPKAVEILAKEIGLLADEIEIYGKSKAKVRLSLLERLKDQADGKYVLVAGITPT PLGEGKSTVTIGLVQALTAHLNVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNL HLTGDIHAITAANNLLAAAIDARILHENTQTDKALYNRLVPSVNGVREFSKIQLARLKRL GINKTDPSALTEEEMRKFARLDIDPSTITWQRVVDTNDRFLRKITIGQANTEKGCSRQAQ FDIAVASEIMAVLALTDSLSDMKERLGRMVVASDRNGQPVTADDLGVTGALTVLMKDAIK PNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGEGGFVVTEAGFGADIGMEKF FNIKCRASGLVPSVVVLVATVRALKMHGGGPSVTAGVPLRKEYTEENLQLVADGCCNLEK QIQIAQLFGVPVVVALNVFKTDTRAEIDLVCELAKRAGAFNAVPCYHWSIGGKGSVDLAW AVREAASKESRFQFLYDVQLPIVEKIRTIAQSVYGAKDIELSPEAQSKIDRYTEQGFGNL PICMAKTHLSLSHQPDKKGVPKGFILPISDVRASIGAGFIYPLVGTMSTMPGLPTRPCFY DIDLDTETEQVKGLF AAI20039.1 Q0VCR7 C1TM_BOVIN BC120038 MTHFD1L