| Identification |
|---|
| BMDB Protein ID
| BMDBP00139 |
| Secondary Accession Numbers
| None |
| Name
| CTD nuclear envelope phosphatase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| CTDNEP1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein serine/threonine phosphatase activity |
| Specific Function
| Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. May antagonize BMP signaling (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 19 |
| Locus
| Not Available |
| SNPs
| CTDNEP1 |
| Gene Sequence
|
>735 bp
ATGATGAGGACGCAGTGTCTGCTGGGGCTGCGCACGTTCGTGGCCTTCGCCGCCAAGCTC
TGGAGCTTCTTCATTTACCTTTTGAGGAGGCAGATCCGCACGGTAATTCAGTACCAAACT
GTTCGATATGACATCCTTCCCTTATCTCCTGTGTCCCGGAATCGGCTAAGCCAGGTGAAG
AGGAAGATCCTGGTGCTGGATCTGGATGAGACACTTATTCACTCCCATCATGATGGGGTC
CTGAGGCCCACAGTCCGGCCTGGAACGCCTCCTGACTTCATTCTCAAGGTGGTAATAGAC
AAACATCCCGTCCGGTTTTTTGTACATAAGAGGCCCCATGTGGATTTCTTCTTGGAAGTG
GTGAGCCAGTGGTACGAGTTGGTGGTGTTCACAGCAAGCATGGAGATTTATGGCTCTGCT
GTGGCAGATAAACTGGATAATAGCAGAAGCATTCTCAAGAGAAGATACTACAGACAACAC
TGCACTTTGGAATTGGGCAGCTACATCAAGGACCTCTCTGTGGTCCACAGTGACCTCTCC
AGCATTGTGATCCTGGATAACTCCCCAGGGGCTTACAGGAGCCATCCAGACAATGCCATC
CCCATCAAATCCTGGTTCAGTGATCCCAGTGATACCGCCCTTCTCAACCTGCTTCCAATG
CTGGATGCCCTCAGGTTCACCGCTGATGTTCGTTCTGTGCTGAGCCGAAACCTTCACCAA
CATAGGCTCTGGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 244 |
| Molecular Weight
| 28393.0 |
| Theoretical pI
| 10.19 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Serine/threonine-protein phosphatase dullard
MMRTQCLLGLRTFVAFAAKLWSFFIYLLRRQIRTVIQYQTVRYDILPLSPVSRNRLSQVK
RKILVLDLDETLIHSHHDGVLRPTVRPGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEV
VSQWYELVVFTASMEIYGSAVADKLDNSRSILKRRYYRQHCTLELGSYIKDLSVVHSDLS
SIVILDNSPGAYRSHPDNAIPIKSWFSDPSDTALLNLLPMLDALRFTADVRSVLSRNLHQ
HRLW
|
| External Links |
|---|
| GenBank ID Protein
| AAI14678.1 |
| UniProtKB/Swiss-Prot ID
| Q1RMV9 |
| UniProtKB/Swiss-Prot Entry Name
| CNEP1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC114677 |
| GeneCard ID
| CTDNEP1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
