Showing Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (BMDBP00140)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 6 metabolites
Identification
BMDB Protein ID BMDBP00140
Secondary Accession Numbers None
Name 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1
Synonyms Not Available
Gene Name PFKFB1
Protein Type Enzyme
Biological Properties
General Function Carbohydrate transport and metabolism
Specific Function Synthesis and degradation of fructose 2,6-bisphosphate.
Pathways
  • Fructose and Mannose Degradation
Reactions
D-Fructose 2,6-bisphosphate + Water → Fructose 6-phosphate + Hydrogen phosphate details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location X
Locus Not Available
SNPs PFKFB1
Gene Sequence 
>1416 bp
ATGTCTCAAGAGATGGGAGAGCTCACCCAAACCAGATTGCAGAAGATCTGGATTCCACAC
AACAACGGCAACAGCAGGCTTCAACGGAGGAGGGGCTCATCCATACCACAGTTTACAAAT
TCCCCCACAATGGTGATCATGGTGGGTTTACCAGCTCGAGGAAAGACCTACATCTCAACA
AAGCTCACACGCTATCTCAACTGGATAGGAACACCAACTAAAGTGTTTAATTTAGGCCAA
TATCGACGAGAGGCAGTGAGCTACAAGAACTACGAATTCTTTCTTCCCGACAACATGGAG
GCCCTACTTATCAGGAAGCAGTGTGCCCTAGCAGCCCTGAAAGATGTTCATAGCTATCTC
AGCCATGAGGAAGGTCGTGTTGCAGTTTTTGATGCCACCAACACTACCAGAGAACGACGG
TCACTGATTCTGCAGTTTGCTAAAGAACATGGTTACAAGGTCTTTTTCATTGAGTCCATT
TGTAATGACCCTGACGTCATTGCAGAAAACATCAGGCAAGTGAAACTTGGCAGTCCTGAT
TATATAGACTGTGATCGTGAAAAGGTTCTGGAAGATTTTCTAAAGAGAATAGAGTGCTAT
GAGGTCAACTACCAACCCTTGGATGATGAACTGGATAGCCACCTGTCCTACATCAAGATC
TTCGACGTGGGCACACGCTACATGGTGAATCGTGTGCAGGACCATATCCAGAGCCGCACA
GTCTACTATCTCATGAACATTCACGTCACACCCCGCTCCATCTACCTATGCCGGCACGGT
GAGAGTGAACTCAACCTCAGAGGCCGCATTGGAGGTGACTCTGGCCTCTCAGCTCGGGGC
AAGCAGTATGCCTATGCCCTGGCCAATTTCATTCAGTCCCAGGGTATCAGCTCACTGAAG
GTTGGGACCAGCCACATGAAGAGGACTATCCAGACAGCTGAAGCCTTAGGACTTCCCTAT
GAGCAATGGAAGGCCCTGAATGAGATTGATGCGGGTGTCTGTGAGGAGATGACCTATGAA
GAAATCCAAGAACACTACCCTGAAGAATTTGCACTGCGAGACCAAGATAAATACCGCTAC
CGCTATCCTAAGGGAGAGTCTTACGAGGATCTGGTCCAGCGTCTGGAGCCAGTTATAATG
GAGCTAGAACGGCAGGAAAATGTATTGGTGATCTGCCATCAGGCTGTCATGCGGTGCCTC
CTGGCCTACTTTCTGGACAAGAGCTCAGATGAGTTGCCTTATCTCAAGTGCCCTCTCCAC
ACAGTGCTCAAACTTACACCTGTGGCTTATGGCTGCAAAGTGGAGTCCATCTACCTGAAT
GTGGAGGCTGTAAACACACATCGGGAGAAACCTGAGAATGTGGACATCACCCGGGAACCT
GAAGAAGCCCTGGACACTGTTCCTGCCCACTACTGA
Protein Properties
Number of Residues 471
Molecular Weight 54657.0
Theoretical pI 6.51
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence 
>6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
MSQEMGELTQTRLQKIWIPHNNGNSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYIST
KLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALLIRKQCALAALKDVHSYL
SHEEGRVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPDVIAENIRQVKLGSPD
YIDCDREKVLEDFLKRIECYEVNYQPLDDELDSHLSYIKIFDVGTRYMVNRVQDHIQSRT
VYYLMNIHVTPRSIYLCRHGESELNLRGRIGGDSGLSARGKQYAYALANFIQSQGISSLK
VGTSHMKRTIQTAEALGLPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY
RYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLH
TVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
GenBank ID Protein AAA30696.1
UniProtKB/Swiss-Prot ID P49872
UniProtKB/Swiss-Prot Entry Name F261_BOVIN
PDB IDs
GenBank Gene ID M64323
GeneCard ID PFKFB1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available