| Identification |
|---|
| BMDB Protein ID
| BMDBP00190 |
| Secondary Accession Numbers
| None |
| Name
| Putative tyrosine-protein phosphatase auxilin |
| Synonyms
|
Not Available
|
| Gene Name
| DNAJC6 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in heat shock protein binding |
| Specific Function
| Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles (PubMed:15502813). Plays a role in clathrin-mediated endocytosis in neurons (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| Not Available |
| SNPs
| DNAJC6 |
| Gene Sequence
|
>2733 bp
ATGGACAGCTCAGGTGCCTCATCTCCAGACATGGAGCCCAGCTATGGCGGAGGTCTTTTT
GACATGGTGAAAGGAGGGGCAGGGAGGCTCTTTAGCAACCTAAAGGACAACTTGAAAGAC
ACTCTCAAAGACACGTCTTCCAGAGTTATACAATCTGTTACCAGCTACACGAAAGGAGAT
TTAGACTTCACTTATGTTACCTCCAGAATTATTGTGATGTCCTTTCCTCTGGACAGTGTT
GACATAGGATTCAGGAATCAGGTTGATGATATTCGAAGCTTTTTGGATTCCAGACATCTT
GACCACTACACGGTATACAATCTGTCGCCCAAGTCTTATCGAACTGCCAAGTTTCACAGC
AGGGTCTCAGAATGCAGTTGGCCCATCAGGCAGGCCCCCAGCCTGCACAACCTCTTTGCT
GTGTGTCGGAATATGTATAACTGGCTACTACAGAATCCCAAAAACGTCTGTGTTGTCCAC
TGCTTGGATGGACGGGCAGCATCATCGATTCTGGTTGGTGCTATGTTCATTTTCTGTAAT
CTCTACTCTACTCCTGGCCCAGCCGTTCGATTGCTCTACGCAAAGCGACCAGGAATTGGA
CTTTCACCATCCCACAGGAGGTACCTGGGCTACATGTGTGACCTCCTAGCAGACAAACCC
TACCGCCCTCACTTCAAGCCTCTCACAATTAAGTCGATCACTGTCAGTCCAGTTCCTTTT
TTCAACAAACAGAGAAATGGATGTCGCCCTTACTGCGATGTACTGATTGGAGAAACCAAA
ATATATACAACCTGTGCAGATTTTGAACGAATGAAGGAATACCGTGTCCAAGATGGAAAA
ATCTTCATTCCTTTGAGCATCACTGTGCAAGGAGATGTGGTTGTTTCCATGTATCACTTG
AGGTCAACAATTGGAAGCAGGCTACAGGCTAAGGTGACCAACACTCAAATATTTCAGCTT
CAGTTTCATACTGGATTCATTCCACTGGACACAACAGTTTTAAAGTTCACCAAGCCTGAG
TTGGATGCATGTGATGTACCAGAAAAATATCCTCAGCTATTTCAGGTAACTCTGGATGTA
GAACTACAGCCTCACGACAAAGTGATGGAGCTAACCCCACCGTGGGAACATTACTGCACA
AAAGATGTCAACCCCAGCATCCTCTTCTCTTCTCACCAGGAGCATCAAGATACTCTGGTC
TTAGGAGGACAGGCTCCAATAGATATCCCTCCAGATAATCCCAGACATTTTGGGCAAGGT
GGCTTCTTTTCCACTCTCTGCTGGCAAGATCAGAAATCGGAGAAGTCATTCTGCGAGGAG
GACCACGCTGCCCTAGTGAATCAGGAGAGTGAGCAGTCAGACGATGAGCTTCTGACGCTG
TCCAGCCCACATGGCAATGCCAATGGTGACAAACCTCACGCAGCCAGGAAGCCCAGCAAA
AAGCAGCAGGAGCCAGCTGCCCCTGCACCCCCTGAGGATGTGGATCTTCTGGGTCTAGAA
GGGTCTGCTGTGAGTAAGAACTTCTCTTCGCCGGCAGCTCCTCCCTCCAATTCCGAACTT
CTGAGTGACCTGTTCGGGGGCGGAGGTGCAGCCGGTCCCGTCCAGTCTGGACAGTCAGGG
GTGGACGACGTGTTTCACCCGAGTGGACCTACATCCACCCAGTCCACACCACGCCGATCT
GCCACCTCCACCTCTGCATCTCCAACACTGAGAGTAGGAGAAGGTGCCACCTTTGACCCA
TTTGGAGCACCTTCTAAACCATCAGGTCAAGATTTGCTGGGTTCTTTTTTGAACACAGCC
AGTGCTTCCAGTGACCCCTTTCTTCAGCCTACGAGGAGTCCTTCTCCTACAGTGCATGCT
TCTAGTACCCCTGCTGTGAACATTCAGCCAGATGTTTCAGGAGCCTGGGACTGGCATACC
AAACCAGGAGGTTTTGGAATGGGAAGCAAATCAGCTGCCACCAGCCCAACAGGCTCCTCG
CATGGTACTCCCACCCATCAAAACAAACCCCAGACTCTGGACCCTTTTGCTGACCTTGGG
ACATTAGGTGGTTCTTCATTTGCCAGCAAACCTTCCACACCAACTGGATTGGGTGGTGGA
TTTCCACCTCTCAGCTCGCCACAGAAAGCATCTCCCCAGCCCATGGGTGGGGGGTGGCAG
CAGGGAGGGGGCTACAACTGGCAGCAGACACAGTCCAAGCCACAGTCCAGCATGCCCCAC
TCCTCTCCCCAGAACCGGCCCAACTACAACGTGAGCTTCTCATCCATGCCTGGGGGCCAG
AACGAACGTGGGAAAGCAGCAGCTAATTTGGAGGGGAAACAAAAAGCAGCTGACTTTGAA
GACCTGCTCTCTGGTCAAGGTTTTAATGCTCACAAAGACAAAAAGGGACCTCGAACAATA
GCTGAGATGAGAAAGGAGGAAATGGCTAAGGAGATGGATCCTGAGAAGTTAAAGATTCTA
GAATGGATTGAAGGCAAAGAGAGGAATATCAGAGCCCTTCTGTCCACAATGCACACTGTG
CTGTGGGCTGGGGAGACTAAGTGGAAACCTGTTGGCATGGCAGACCTGGTCACCCCGGAG
CAGGTGAAGAAGGTGTACAGGAAGGCTGTGCTAGTGGTGCACCCGGATAAAGCTACTGGG
CAACCCTATGAACAATATGCAAAGATGATTTTCATGGAGCTCAATGATGCCTGGTCAGAA
TTTGAAAATCAAGGCCAAAAGCCCTTGTATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 910 |
| Molecular Weight
| 99512.0 |
| Theoretical pI
| 7.27 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Putative tyrosine-protein phosphatase auxilin
MDSSGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYTKGD
LDFTYVTSRIIVMSFPLDSVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHS
RVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCN
LYSTPGPAVRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSPVPF
FNKQRNGCRPYCDVLIGETKIYTTCADFERMKEYRVQDGKIFIPLSITVQGDVVVSMYHL
RSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDV
ELQPHDKVMELTPPWEHYCTKDVNPSILFSSHQEHQDTLVLGGQAPIDIPPDNPRHFGQG
GFFSTLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHAARKPSK
KQQEPAAPAPPEDVDLLGLEGSAVSKNFSSPAAPPSNSELLSDLFGGGGAAGPVQSGQSG
VDDVFHPSGPTSTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTA
SASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGAWDWHTKPGGFGMGSKSAATSPTGSS
HGTPTHQNKPQTLDPFADLGTLGGSSFASKPSTPTGLGGGFPPLSSPQKASPQPMGGGWQ
QGGGYNWQQTQSKPQSSMPHSSPQNRPNYNVSFSSMPGGQNERGKAAANLEGKQKAADFE
DLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTV
LWAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYEQYAKMIFMELNDAWSE
FENQGQKPLY
|
| External Links |
|---|
| GenBank ID Protein
| AAA79037.1 |
| UniProtKB/Swiss-Prot ID
| Q27974 |
| UniProtKB/Swiss-Prot Entry Name
| AUXI_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| U09237 |
| GeneCard ID
| DNAJC6 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
