| Identification |
|---|
| BMDB Protein ID
| BMDBP00196 |
| Secondary Accession Numbers
| None |
| Name
| Probable phospholipid-transporting ATPase IA |
| Synonyms
|
Not Available
|
| Gene Name
| ATP8A1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Inorganic ion transport and metabolism |
| Specific Function
| May play a role in the transport of aminophospholipids from the outer to the inner leaflet of various membranes and the maintenance of asymmetric distribution of phospholipids, mainly in secretory vesicles. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 6 |
| Locus
| Not Available |
| SNPs
| ATP8A1 |
| Gene Sequence
|
>3450 bp
ATGCCCACCATGCGGAGGACCGTGTCGGAGATCCGGTCCCGAGCCGAGGGTTATGAGAAG
ACTGATGATGTTTCAGAGAAGACGTCACTGGCTGACCAGGAAGAAATAAGGACTATATTC
ATCAACCAGCCTCAGCTGACAAAATTCTGCAATAACCATGTCAGCACTGCAAAATACAAC
ATAATCACATTCCTTCCAAGATTTCTCTACTCTCAGTTCAGAAGAGCCGCTAATTCATTT
TTTCTCTTTATTGCACTGCTCCAGCAAATACCTGATGTATCACCAACAGGTCGCTATACA
ACACTGGTTCCTCTCTTATTTATTTTGGCTGTGGCAGCTATCAAAGAGATAATAGAAGAT
ATTAAACGACATAAAGCTGATAATGCAGTAAACAAGAAGCAGACACAAGTTTTAAGAAAT
GGTGCTTGGGAAATTGTGCACTGGGAAAAGGTAAATGTTGGAGATATAGTTATAATAAAA
GGCAAAGAGTATATACCTGCTGACACTGTACTTCTCTCATCAAGTGAGCCCCAGGCCATG
TGTTACATTGAAACATCCAACTTAGATGGTGAAACAAACCTGAAAATTAGACAGGGCTTA
CCAGCAACATCAGATATAAAAGACATTGACAGTTTGATGAGACTGTCTGGCAGAATTGAG
TGTGAAAGTCCAAACAGACATCTCTATGATTTTGTTGGAAACATACGGCTTGATGGACGC
AGCACTGTTCCCCTGGGAGCAGACCAGATTCTTCTGCGAGGTGCTCAATTGAGAAATACA
CAGTGGGTTCATGGAATAGTTGTCTACACTGGACATGACACCAAGCTAATGCAGAACTCA
ACAAGTCCACCACTTAAACTCTCAAATGTCGAAAGGATTACAAATGTACAAATTTTGATT
TTATTTTGTATCTTGATTGCCATGTCTCTTGTCTGTTCTGTGGGCTCAGCCATTTGGAAT
CGAAGGCATTCTGGAAGGGACTGGTATCTCAATCTAAACTATGGTGGTGCTAATAATTTT
GGACTGAATTTCTTGACGTTCATCATCCTTTTCAATAACCTCATTCCTATCAGCTTGCTG
GTGACATTAGAAGTGGTGAAATTTACCCAGGCATACTTCATAAATTGGGATCTTGACATG
CACTATGAACCAACTGACACTGCTGCTATGGCTCGAACATCTAATCTGAATGTGGAACTT
GGCCAGGTGAAATATATATTTTCTGACAAAACTGGTACTTTGACATGCAATGTAATGCAG
TTTAAGAAGTGCACCATAGCCGGAGTGGCTTACGGGCAGAACTCACAGTTTGGAGATGAA
AAAACATTTAGTGATTCATCATTGCTGGAAAACCTCCAAAATAATCATCCCACTGCACCA
ATAATATGTGAATTTCTTACAATGATGGCCGTGTGTCACACGGCAGTACCAGAGCGGGAA
GGTGATAAGATAATTTACCAGGCAGCATCTCCAGATGAGGGAGCCTTGGTCAGAGCAGCC
AAGCAGTTGAATTTTGTTTTCACTGGAAGAACGCCTGACTCAGTGATTATAGATTCACTG
GGGCAGGAAGAAAGATATGAATTGCTCAATGTCTTGGAGTTCACCAGCGCTAGAAAAAGA
ATGTCAGTGATCGTTCGCACTCCATCCGGGAAGTTACGACTTTACTGCAAAGGAGCCGAC
ACTGTAATTTATGACCGACTGGCAGAAACTTCAAAATACAAAGAAATTACCCTAAAACAT
TTGGAGCAGTTTGCTACAGAAGGGTTAAGAACCTTGTGTTTTGCCGTGGCTGAGATTTCA
GAGAGCGACTTTCAGGAGTGGCGAGCCGTCTATCACCGTGCCTCCACATCTGTGCAGAAC
AGGCTGCTCAAACTCGAAGAGAGCTACGAGTTAATCGAAAAGAATCTTCAACTACTGGGA
GCCACAGCCATTGAGGATAAATTACAAGATCAAGTGCCTGAAACCATAGAAACTCTAATG
AAAGCAGACATCAAAATCTGGATCCTTACAGGAGACAAGCAGGAAACTGCCATTAACATT
GGGCACTCCTGCAAACTTCGGAGGAAGAACATGGGAATGATTGTTATAAATGAAGGCTCT
CTTGATGGAACACGGGAAACTCTCAGTCGTCACTGCACTACTCTGGGTGATGCTCTTCGG
AAGGAGAATGACTTTGCTCTTATAATTGATGGGAAAACCCTCAAATATGCCTTAACTTTT
GGAGTGAGGCAGTATTTCCTGGACTTAGCTTTGTCGTGCAAAGCTGTTATTTGCTGCAGG
GTTTCTCCTCTTCAAAAATCTGAAGTTGTGGAGATGGTTAAGAAACAAGTTAAAGTCATA
ACACTCGCCATTGGTGATGGAGCAAATGACGTCAGTATGATACAGACGGCACATGTTGGA
GTAGGAATAAGTGGCAATGAAGGCCTTCAGGCAGCTAATTCTTCTGACTACTCTATAGCT
CAGTTCAAATATTTGAAGAATTTGTTGATGGTTCATGGTGCCTGGAACTATAACAGAGGC
TCCAAGTGTATCTTATACTGCTTCTACAAGAATATAGTCCTCTATATTATCGAGATCTGG
TTTGCCTTCGTGAATGGCTTTTCTGGACAGATCCTCTTTGAGAGATGGTGCATAGGTCTT
TATAATGTGATGTTTACAGCAATGCCACCCTTAACTCTGGGAATATTTGAGAGATCATGC
AGAAAGGAGTATATGTTGAAGTATCCTGAATTATACAAAACATCTCAGAATGCCCTGGAC
TTCAACACCAAGGTTTTCTGGGTTCATTGTTTAAATGGCCTCTTCCACTCAGTTATTCTG
TTTTGGTTTCCACTAAAAGCCCTTCAATATGGCACTGTATTTGAAAATGGGAGAACTTCT
GATTACCTGCTGTTGGGAAACTTCGTTTACACATTTGTGGTGATAACTGTGTGCTTGAAA
GCTGGATTGGAGACATCATATTGGACCTGGTTCAGCCACATAGCCATCTGGGGCAGCATC
GCACTCTGGGTGGTGTTTTTTGGAATCTACTCATCTCTGTGGCCTGCTGTTCCAATGGCC
CCTGATATGTCAGGAGAGGCAGCCATGTTGTTCAGTTCTGGAGTCTTTTGGATGGGCCTG
TTATTTATCCCTGTGGCCTCCTTGCTCCTTGATGTGGTGTATAAAGTTATCAAGAGGACT
GCTTTTAAAACATTAGTAGATGAAGTTCAGGAGCTGGAGGCAAAATCTCAAGACCCAGGA
GCAGTTGTGCTTGGAAAAAGCCTCACAGAGAGGGCGCAACTGCTCAAGAACGTCTTTAAG
AAGAACCACGTGAACTTGTACCGGTCAGAATCACTGCAACAAAACCTGCTCCATGGGTAT
GCTTTCTCTCAAGATGAAAATGGAATCGTCTCACAGTCTGAAGTGATTAGAGCATATGAT
ACCACAAAGCAGAGACCTGATGAGTGGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 1149 |
| Molecular Weight
| 130026.0 |
| Theoretical pI
| 7.58 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 66-86
- 93-115
- 298-319
- 345-366
- 843-863
- 876-895
- 926-947
- 962-984
- 991-1011
- 1030-1055
|
| Protein Sequence
|
>Probable phospholipid-transporting ATPase IA
MPTMRRTVSEIRSRAEGYEKTDDVSEKTSLADQEEIRTIFINQPQLTKFCNNHVSTAKYN
IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED
IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPADTVLLSSSEPQAM
CYIETSNLDGETNLKIRQGLPATSDIKDIDSLMRLSGRIECESPNRHLYDFVGNIRLDGR
STVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI
LFCILIAMSLVCSVGSAIWNRRHSGRDWYLNLNYGGANNFGLNFLTFIILFNNLIPISLL
VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNVELGQVKYIFSDKTGTLTCNVMQ
FKKCTIAGVAYGQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPERE
GDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKR
MSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEIS
ESDFQEWRAVYHRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLM
KADIKIWILTGDKQETAINIGHSCKLRRKNMGMIVINEGSLDGTRETLSRHCTTLGDALR
KENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVI
TLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMVHGAWNYNRG
SKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSC
RKEYMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTVFENGRTS
DYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLWPAVPMA
PDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQELEAKSQDPG
AVVLGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQDENGIVSQSEVIRAYD
TTKQRPDEW
|
| External Links |
|---|
| GenBank ID Protein
| AAD03352.1 |
| UniProtKB/Swiss-Prot ID
| Q29449 |
| UniProtKB/Swiss-Prot Entry Name
| AT8A1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| U51100 |
| GeneCard ID
| ATP8A1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
