1.0 2018-05-07 22:21:19 UTC 2020-05-20 21:06:58 UTC BMDBP00207 Enzyme ATP2A1 Inorganic ion transport and metabolism Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (PubMed:22387132). Contributes to calcium sequestration involved in muscular excitation/contraction. Muscle/Heart Contraction SMP0119378 BMDB0000464 Calcium BMDB0000547 Magnesium BMDB0001341 ADP BMDB0001429 Phosphate 25 >2982 bp ATGGAGGCTGCGCACTCCAAGACCACAGAAGAATGTTTGGCCTATTTTGGGGTGAGCGAA ACTACAGGCCTCACCCCGGACCAAGTTAAGCGGCATCTGGAGAAATATGGCCATAATGAG CTCCCTGCTGAGGAGGGGAAGTCCCTGTGGGAGCTGGTGTTAGAGCAGTTTGAAGACCTC CTGGTGCGGATCCTTCTCCTGGCCGCCTGCATTTCCTTTGTGCTGGCCTGGTTTGAGGAA GGCGAAGAGACTGTCACCGCCTTTGTTGAACCCTTTGTCATCCTCTTGATCCTCATTGCC AATGCCATCGTGGGGGTTTGGCAGGAGCGGAATGCAGAGAATGCCATCGAGGCTCTGAAG GAATATGAACCCGAGATGGGGAAGGTCTACCGGGCTGACCGCAAGTCAGTACAAAGGATC AAAGCTCGGGATATTGTTCCTGGAGACATCGTGGAGGTGGCTGTGGGGGACAAGGTCCCG GCAGATATCCGCATCCTCACCATCAAGTCTACCACCCTCCGGGTCGACCAGTCCATCCTG ACAGGCGAGTCTGTCTCTGTCATCAAGCACACAGAACCTGTTCCCGACCCCCGAGCTGTC AACCAGGATAAGAAGAACATGCTTTTCTCGGGCACCAACATCGCAGCCGGCAAGGCCATC GGCATTGTGGCCACCACCGGTGTGGGCACCGAGATTGGGAAGATCCGTGACCAAATGGCC GCCACAGAGCAGGACAAGACCCCTCTGCAGCAAAAGCTGGATGAGTTTGGGGAGCAGCTC TCCAAGGTCATCTCCCTCATCTGCGTGGCCGTCTGGCTCATCAACATTGGCCACTTCAAC GACCCCGTGCATGGGGGCTCCTGGATCCGTGGTGCCATCTACTACTTTAAGATCGCCGTG GCCCTGGCTGTGGCTGCCATCCCCGAGGGCCTTCCTGCAGTCATCACCACCTGCCTGGCC TTGGGCACCCGCCGGATGGCAAAGAAGAACGCGATCGTGAGGAGCCTGCCCTCCGTGGAG ACTCTGGGCTGCACCTCTGTCATCTGTTCCGACAAGACGGGCACCCTCACCACCAACCAG ATGTCTGTCTGCAAGATGTTCATCATCGACAGGATAGATGGGGACCTCTGCCTGCTGAAC GAGTTCTCTGTCACTGGCTCCACTTACGCTCCTGAAGGAGAGGTCTTGAAGAATGATAAG CCAGTCCGCTCAGGGCAGTATGACGGGCTGGTGGAGCTGGCCACCATTTGTGCCCTCTGC AATGACTCCTCCTTGGACTTCAATGAGACCAAAGGTATTTATGAGAAGGTGGGAGAGGCC ACCGAGACAGCCCTCACCACCCTGGTGGAGAAGATGAATGTATTCAACACTGAAGTGAGA AACCTCTCGAAGGTAGAGAGGGCCAACGCCTGCAACTCGGTGATCCGCCAGCTAATGAAG AAGGAATTCACCCTGGAGTTCTCCCGGGACCGAAAGTCCATGTCTGTCTATTGCTCTCCA GCAAAATCCCGGGCTGCTGTGGGCAATAAGATGTTTGTCAAGGGTGCCCCTGAGGGGGTC ATCGATCGCTGTAACTACGTGCGAGTGGGCACCACCCGGGTGCCCATGACAGGGCCGGTG AAGGAGAAGATTCTGTCGGTGATCAAAGAGTGGGGTACTGGCCGGGACACCCTGCGCTGC CTGGCGCTGGCCACTCGGGACACCCCCCCCAAGCGAGAGGAGATGGTCCTGGATGACTCT ACCAAGTTCATGGAGTACGAGACGGACTTGACATTCGTTGGCGTCGTGGGCATGCTGGAC CCGCCCCGCAAGGAGGTCATGGGCTCCATCCAACTATGCCGAGACGCTGGAATCCGAGTA ATCATGATCACCGGAGACAACAAGGGCACGGCCATTGCCATCTGCCGACGGATTGGCATC TTCGGGGAGAACGAGGATGTGGCTGACCGGGCCTACACTGGCCGGGAGTTCGATGACCTG CCCCTGGCCGAGCAGCGGGAGGCCTGCCGACGCGCCTGCTGCTTCGCCCGCGTGGAGCCC ACCCACAAGTCGAAGATCGTGGAGTATCTGCAGTCCTTCGATGAGATCACGGCGATGACA GGTGATGGCGTCAATGACGCCCCTGCGCTGAAGAAGGCGGAAATCGGCATTGCCATGGGA TCCGGCACTGCCGTGGCCAAGACAGCCTCTGAGATGGTGCTGGCCGACGACAACTTCTCC ACCATTGTGGCTGCCGTGGAGGAGGGCCGGGCCATCTACAACAACATGAAGCAGTTTATC CGCTACCTCATCTCCTCCAACGTGGGCGAGGTGGTCTGCATCTTCCTGACAGCTGCCCTG GGGCTGCCCGAGGCCCTGATCCCTGTGCAGCTGCTGTGGGTGAACCTGGTGACCGATGGG CTCCCAGCCACAGCCCTGGGCTTCAACCCCCCAGACCTGGACATCATGGACCGGCCCCCC CGGACCCCCAAGGAGCCCCTCATCAGTGGCTGGCTCTTCTTCCGCTACATGGCAATTGGG GGCTATGTGGGTGCAGCCACCGTGGGAGCAGCGGCCTGGTGGTTCCTGTATGCTGAGGAC GGGCCTCACGTCACCTACAGCCAGCTGACTCACTTCATGAAGTGCTCGGAGCACAGCCCA GACTTCGAGGGTGTGGACTGTGAGGTCTTCGAGGCCCCGCAGCCCATGACCATGGCCTTG TCTGTGCTGGTCACCATCGAGATGTGCAATGCTCTCAACAGCCTGTCTGAGAATCAGTCC CTCGTGCGGATGCCACCCTGGGTGAACATCTGGCTGGTGGGCTCCATCGGCCTCTCCATG TCCCTCCACTTCCTCATCCTCTACGTGGACCCTCTGCCGATGATCTTCAAGCTCCAAGCC CTGGACCTGTACCATTGGCTCATGGTCCTCAAGATCTCATTACCAGTCATTGGGCTCGAC GAAATCCTCAAGTTCGTTGCTCGAAACTACCTGGAGGGATAA 993 109290.0 4.93 49-69 90-110 254-273 296-313 757-776 787-807 828-850 897-916 930-948 964-984 None >Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 MEAAHSKTTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVLEQFEDL LVRILLLAACISFVLAWFEEGEETVTAFVEPFVILLILIANAIVGVWQERNAENAIEALK EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILTIKSTTLRVDQSIL TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKAIGIVATTGVGTEIGKIRDQMA ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAV ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ MSVCKMFIIDRIDGDLCLLNEFSVTGSTYAPEGEVLKNDKPVRSGQYDGLVELATICALC NDSSLDFNETKGIYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMK KEFTLEFSRDRKSMSVYCSPAKSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPV KEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSTKFMEYETDLTFVGVVGMLD PPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEDVADRAYTGREFDDL PLAEQREACRRACCFARVEPTHKSKIVEYLQSFDEITAMTGDGVNDAPALKKAEIGIAMG SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL GLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRTPKEPLISGWLFFRYMAIG GYVGAATVGAAAWWFLYAEDGPHVTYSQLTHFMKCSEHSPDFEGVDCEVFEAPQPMTMAL SVLVTIEMCNALNSLSENQSLVRMPPWVNIWLVGSIGLSMSLHFLILYVDPLPMIFKLQA LDLYHWLMVLKISLPVIGLDEILKFVARNYLEG AAI19939.1 Q0VCY0 AT2A1_BOVIN 3TLM 3TLM BC119938 ATP2A1