1.0 2018-05-07 22:21:30 UTC 2020-05-20 21:00:33 UTC BMDBP00249 Enzyme ZDHHC21 Involved in zinc ion binding Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptor (By similarity). BMDB0001338 Palmityl-CoA 8 >798 bp ATGGGTCTCCGGATTCACTTTGTTGTTGACCCACATGGTTGGTGCTGCATGGGTTTGATT GTCTTTGTCTGGTTATACAACTTTTTTTTAATTCCTAAGATTGTCCTCTTTCCTCACTAT GAAGAAGGACATATTCCAGGCATATTAATAATAATATTCTATGGCATTGCCATGTTTTGT CTGGTTGCTTTAGTGAGGGCCTCAATAACTGATCCAGGAAGACTCCCTGAGAACCCAAAG ATCCCACATGGAGAAAGGGAGTTCTGGGAATTGTGTAACAAGTGTAATTTGATGAGACCG AAGCGTTCCCATCACTGCAGCCGCTGCGGCCACTGTGTTAGGAGAATGGATCATCACTGC CCATGGATTAACAATTGTGTTGGTGAAGATAACCATTGGCTTTTTCTGCAATTGTGTTTC TACACTGAACTTCTTACTTGCTACGCACTGATGTTTTCTTTCTGCCACTATTATTACTTT CTTCCGCTAAAAAAGCGTAATTTGGACCTCTTTGTTGTCAGACATGAATTGGCCATAATG AGACTAGCTGCCTTTATGGGCATTACAATGTTAGTTGGAATAACTGGACTGTTTTATACT CAACTAATTGGCATCATCACAGATACAACATCTATTGAAAAGATGTCAAACTGTTGTGAA GAAATATCGAGGCCCCGAAAGCCATGGCAGCAGACCTTCTCAGAAGTTTTTGGCACTCGT TGGAAGATCCTGTGGTTTATTCCTTTCAGGCGGAGGCAACCACTGCGAGTTCCCTACCAC TTTGCCAATCACGTCTAA 265 31463.0 8.59 17-37 45-65 134-154 186-206 None >Probable palmitoyltransferase ZDHHC21 MGLRIHFVVDPHGWCCMGLIVFVWLYNFFLIPKIVLFPHYEEGHIPGILIIIFYGIAMFC LVALVRASITDPGRLPENPKIPHGEREFWELCNKCNLMRPKRSHHCSRCGHCVRRMDHHC PWINNCVGEDNHWLFLQLCFYTELLTCYALMFSFCHYYYFLPLKKRNLDLFVVRHELAIM RLAAFMGITMLVGITGLFYTQLIGIITDTTSIEKMSNCCEEISRPRKPWQQTFSEVFGTR WKILWFIPFRRRQPLRVPYHFANHV AAI33396.1 A2VDT6 ZDH21_BOVIN BC133395 ZDHHC21