| Identification |
|---|
| BMDB Protein ID
| BMDBP00339 |
| Secondary Accession Numbers
| |
| Name
| Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| SDHA |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (Probable). Can act as a tumor suppressor (By similarity). |
| Pathways
|
- Carbohydrate metabolism
- Fumarate from succinate (eukaryal route): step 1/1
- Tricarboxylic acid cycle
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| SDHA |
| Gene Sequence
|
>1998 bp
ATGTCGGGGGTTGCCGCTGTGTCGCGCTTGTGGCGCGCCCGGCGCCTGGCGCTGACCTGC
ACGAAGTGGTCGGCAGCATGGCAGACAGGAACCCGCAGTTTTCACTTCACCGTTGATGGC
AATAAGAGGTCGTCCGCTAAAGTTTCAGATGCGATTTCTGCGCAGTATCCAGTTGTGGAC
CATGAGTTTGATGCCGTGGTGGTTGGTGCCGGGGGGGCAGGCCTGCGGGCCGCGTTCGGC
CTCTCTGAAGCAGGTTTCAACACGGCCTGCGTCACGAAGCTCTTCCCCACCAGATCCCAC
ACTGTCGCGGCCCAGGGAGGGATCAATGCCGCCCTGGGGAACATGGAGGAGGACAACTGG
CGGTGGCACTTCTACGACACCGTGAAAGGCTCCGACTGGCTGGGGGACCAGGACGCCATC
CATTACATGACCGAGCAGGCCCCCGCCTCTGTGGTGGAGCTGGAGAATTACGGCATGCCC
TTTAGCAGAACTGAAGATGGCAAGATCTACCAGCGTGCCTTTGGCGGACAGAGCCTCAAG
TTCGGGAAGGGTGGGCAGGCCCATCGCTGCTGCTGCGTGGCCGACCGCACGGGCCACTCG
CTGCTGCACACGTTGTATGGAAGGTCTCTGCGCTATGACACCAGCTACTTTGTGGAGTAC
TTTGCTCTGGACCTCCTGATGGAGAGCGGGGAGTGCCGCGGTGTGATCGCTCTGTGCATA
GAAGAACGGGTCCATCCACCGCATCAGGGCCAGGAACACTGTCATCGCCACCGGAGCTAC
GGGCGCACCTACTTCAGCTGCACGTCCGCCCACACCAGCACCGGGGACGGCACTGCCATG
GTGACCAGGGCTGGCCTGCCCTGCCAGGACCTGGAGTTCGTGCAGTTCCACCCCACAGGC
ATATATGGCGCTGGCTGTCTCATCACAGAGGGCTGTCGTGGAGAGGGGGGCATCCTCATC
AACAGCCAGGGTGAGAGGTTCATGGAGCGCTACGCCCCCGTCGCTAAGGACCTGGCGTCC
AGGGATGTCGTGTCCCGGTCCATGACCCTGGAAATCCGCGAGGGAAGAGGCTGTGGGCCC
GAGAAGGACCATGTGTACCTGCAGCTGCACCACCTGCCCCCAGCACAGCTGGCTATGCGC
CTGCCTGGCATCTCAGAGACGGCCATGATCTTCGCGGGCGTGGACGTCACCAAGGAGCCC
ATCCCCGTGCTTCCCACCGTGCACTACAACATGGGTGGCATCCCCACCAACTACAAGGGG
CAGGTTCTGAGGCACGTGAATGGCCAGGACCAGGGTGTGCCTGGCCTGTACGCATGCGGG
GAGGCTGCCTGCGCCTCGGTGCATGGTGCCAACCGTCTGGGTGCAAACTCGCTCCTGGAC
CTGGTTGTCTTCGGCCGGGCGTGCGCCCTGAGCATCGCAGAGTCCTGCAGACCCGGAGAT
AAAGTTCCCTCGATTAAACCAAATGCTGGGGAAGAATCTGTCATGAATCTTGACAAATTG
AGATTTGCCAATGGAAGCATAAGGACATCGGAACTGCGACTCAACATGCAGAAGTCGATG
CAGAGCCATGCCGCGGTGTTCCGTGTGGGGAGTGTGCTGCAGGAAGGCTGTGAGAAGATC
AGCAGCCTCTACGGAGACCTGCGGCATCTGAAGACGTTCGACAGGGGAATGGTCTGGAAC
ACTGACCTGGTGGAGACCCTGGAGCTGCAGAACCTGATGCTTTGTGCTCTGCAGACCATC
TACGGAGCGGAGGCCCGGAAGGAGTCGCGCGGCGGCCCACGCAGGGAGGACTTCAAGGAG
AGGGTTGACGAGTACGATTACTCCAAGCCCATCCAGGGGCAGCAGAAGAAGCCCTTTGAG
CAGCACTGGAGGAAGCACACGCTCTCCTACGTTGACATCAAGACTGGGAAGGTCACCCTG
GAGTACAGACCTGTAATCGACAGAACTTTGAACGAGACTGACTGCGCCACTGTTCCCCCA
GCCATCGGCTCCTACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 665 |
| Molecular Weight
| 72944.0 |
| Theoretical pI
| 7.63 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
MSGVAAVSRLWRARRLALTCTKWSAAWQTGTRSFHFTVDGNKRSSAKVSDAISAQYPVVD
HEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNW
RWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGKIYQRAFGGQSLK
FGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMESGECRGVIALCI
EDGSIHRIRARNTVIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTG
IYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGP
EKDHVYLQLHHLPPAQLAMRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKG
QVLRHVNGQDQGVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGD
KVPSIKPNAGEESVMNLDKLRFANGSIRTSELRLNMQKSMQSHAAVFRVGSVLQEGCEKI
SSLYGDLRHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGGPRREDFKE
RVDEYDYSKPIQGQQKKPFEQHWRKHTLSYVDIKTGKVTLEYRPVIDRTLNETDCATVPP
AIGSY
|
| External Links |
|---|
| GenBank ID Protein
| AAA30758.1 |
| UniProtKB/Swiss-Prot ID
| P31039 |
| UniProtKB/Swiss-Prot Entry Name
| SDHA_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| M60879 |
| GeneCard ID
| SDHA |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
