| Identification |
|---|
| BMDB Protein ID
| BMDBP00362 |
| Secondary Accession Numbers
| None |
| Name
| Citrate synthase, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| CS |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Not Available |
| Pathways
|
- Carbohydrate metabolism
- Citric Acid Cycle
- Isocitrate from oxaloacetate: step 1/2
- LPS and Citrate Signaling and Inflammation
- Transfer of Acetyl Groups into Mitochondria
- Tricarboxylic acid cycle
- Warburg Effect
|
| Reactions
|
| Acetyl-CoA + Water + Oxalacetic acid → Citric acid + Coenzyme A |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| 5p |
| SNPs
| CS |
| Gene Sequence
|
>1401 bp
ATGGCTTTACTCACTGCGGCCGCCCGGCTATTCGGAGCTAAGAATGCATCCTGTCTTGTT
CTTGCTGCCAGGCATGCCAGTGCTTCTTCCACGAATTTGAAAGACATATTGGCTGATCTG
ATACCTAAGGAGCAGACCAGAGTGAAGGCCTTCAGGCAGCAACATGGCAAGACGGTGGTG
GGCCAGATCACTGTGGACATGATGTATGGTGGCATGCGAGGCATGAAGGGATTGGTATAT
GAAACATCAGTTCTTGATCCTGATGAGGGCATCCGTTTTAGAGGCTACAGCATCCCTGAA
TGCCAGAAACTGCTGCCAAAGGCTAAAGGGGGCGAAGAACCCTTGCCAGAGGGCTTATTT
TGGCTGCTGGTAACTGGACAAATCCCAACAGAGGAACAGGTATCTTGGCTCTCACAGGAG
TGGGCAAAGAGGGCAGCTCTGCCTTCCCACGTGGTCACCATGCTGGACAACTTTCCCACT
AATCTACACCCCATGTCTCAGCTCAGTGCAGCTGTTACAGCTCTCAACAGTGAAAGTACC
TTTGCCCGAGCATATTCAGAGGGTATCAACCGAACCAAGTACTGGGAGTTGATTTATGAA
GACTCTATGGATCTGATCGCAAAGCTTCCTTGTGTTGCAGCAAAGATCTACCGGAACCTG
TACCGAGAGGGCAGCAGTATTGGGGCCATTGACCCTAAGCTGGACTGGTCCCACAATTTC
ACCAACATGTTAGGCTATACTGACGCTCAGTTCACAGAGCTCATGCGCTTGTACCTCACC
ATCCACAGTGACCATGAAGGTGGCAACGTAAGTGCCCACACCAGCCACTTGGTGGGCAGT
GCCCTTTCAGACCCCTATTTGTCCTTTGCAGCAGCCATGAATGGGCTGGCAGGGCCCCTG
CATGGACTGGCAAATCAGGAAGTGCTTGTTTGGCTGACACAACTTCAGAAGGAAGTTGGC
AAAGATGTGTCAGATGAGAAGTTACGAGACTACATCTGGAACACACTCAACTCAGGACGG
GTTGTCCCGGGCTATGGCCATGCAGTACTAAGGAAGACTGATCCACGATATACCTGTCAA
CGAGAGTTTGCTCTGAAACACCTGCCTCAGGACCCCATGTTTAAGCTGGTTGCTCAGCTG
TACAAGATTGTGCCCAATATCCTCCTAGAGCAGGGCAAGGCAAAGAATCCGTGGCCCAAT
GTAGATGCTCACAGCGGGGTGCTGCTCCAGTACTACGGCATGACGGAGATGAATTACTAC
ACAGTCCTGTTTGGGGTATCACGGGCACTAGGTGTATTAGCACAGCTCATTTGGAGCCGA
GCCCTAGGCTTCCCTCTAGAAAGACCCAAGTCCATGAGCACAGATGGTCTGATGAAGTTT
GTGGACTCTAAGTCAGGGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 466 |
| Molecular Weight
| 51773.0 |
| Theoretical pI
| 8.29 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 21-42
- 54-73
- 94-110
- 116-133
- 145-167
- 193-216
- 223-244
- 256-277
- 284-303
- 309-330
- 351-369
- 389-414
|
| Protein Sequence
|
>Citrate synthase, mitochondrial
MALLTAAARLFGAKNASCLVLAARHASASSTNLKDILADLIPKEQTRVKAFRQQHGKTVV
GQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKLLPKAKGGEEPLPEGLF
WLLVTGQIPTEEQVSWLSQEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSEST
FARAYSEGINRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSSIGAIDPKLDWSHNF
TNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPL
HGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQ
REFALKHLPQDPMFKLVAQLYKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYY
TVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLMKFVDSKSG
|
| External Links |
|---|
| GenBank ID Protein
| AAI14139.1 |
| UniProtKB/Swiss-Prot ID
| Q29RK1 |
| UniProtKB/Swiss-Prot Entry Name
| CISY_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC114138 |
| GeneCard ID
| CS |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
