| Identification |
|---|
| BMDB Protein ID
| BMDBP00366 |
| Secondary Accession Numbers
| |
| Name
| 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| GCAT |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Coenzyme transport and metabolism |
| Specific Function
| Not Available |
| Pathways
|
- Amino-acid degradation
- Glycine from L-threonine: step 2/2
- L-threonine degradation via oxydo-reductase pathway
|
| Reactions
|
| Palmityl-CoA + L-Serine → 3-Dehydrosphinganine + Carbon dioxide |
details
|
| Acetyl-CoA + Glycine → L-2-Amino-3-oxobutanoic acid + Coenzyme A |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| GCAT |
| Gene Sequence
|
>1260 bp
ATGTGGGCTGGCCGCGTCCTGCATGCTGCGCTCTCCCGGGCCCCCCGCGAGAGCCGGGCG
CAGTCAGCGCTGGCTCAGCTGCGTGGCATCCTGGAGGAGGAGCTGGAAAGCATCCGCGGA
GCTGGCACCTGGAAGAGCGAGCGGGTCATCACGTCCCGTCAGGGGCCGCACATCCACGTG
GACGGCGCCCCGGGAGGAATTATTAACTTCTGTGCCAACAACTACCTGGGCCTGAGCAGC
CACCCTGAGGTCATTCAGGCAGGTCTGCGGACCCTAAAGGAGTTTGGAGCCGGCCTTAGC
TCAGTCCGCTTCATCTGTGGCACCCAGAGCATCCACAAAGACCTAGAAGCAAAGATAGCC
CGCTTTCACCAAAGGGAGGATGCCATCCTCTATCCCAGCTGTTTTGATGCCAACACCGGC
CTCTTTGAGGCACTGCTGACTTCGGAGGACGCAGTCCTGTCGGATGAGCTGAACCATGCC
TCCATCATCGATGGCATCCGTCTGTGCAAGGCCCACAAGTACCGCTACCGCCACCTGGAT
ATGGCTGATCTGGAGGCCAAGCTGCAGGAGGCCCAGAAGCATCGGCTGCGCCTGGTGGCC
ACTGATGGGGCCTTTTCCATGGATGGTGACATCGCACCCCTGCAGGAGATCTGCCGCCTT
GCCTCTCAATATGGTGCCTTAGTCTTTGTGGACGAAAGCCACGCCACTGGCTTCCTGGGG
GCCACAGGACGGGGCACAGATGAGCTGCTGGGCGTGATGGACCAAGTCACCATCATCAAC
TCCACACTGGGGAAGGCCCTGGGTGGAGCATCAGGGGGCTACACGACTGGGCCTGGGGCC
CTGGTATCCCTGCTACGGCAGCGTGCCCGGCCCTACCTCTTCTCCAACAGCCTGCCCCCT
GCTGCTGTCGGCTGTGCCTCCAAGGCCCTGGACCTGCTCATGGAGAGCAACGCCATCGTC
CAGTCTATGGCGGCCAAGACCCTGCGATTCCGCAGTCAGATGGAGGCTGCTGGCTTCACC
ATCTCAGGAGCCAATCACCCCATCTGCCCTGTGATGCTGGGTGACGCTCGGCTGGCCTTA
AACATAGCGGATGACATGCTTAAGAGAGGCATCTTTGTCATTGGGTTCAGCTACCCTGTG
GTCCCCAAAGGCAAGGCCCGGATCCGAGTCCAGATCTCAGCAGTGCACAGTGAGGAGGAC
ATTGACCGCTGTGTGGAGGCCTTCGTGGAGGTGGGGCGACTGCACGGCGCGCTGCCTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 419 |
| Molecular Weight
| 45166.0 |
| Theoretical pI
| 7.38 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
MWAGRVLHAALSRAPRESRAQSALAQLRGILEEELESIRGAGTWKSERVITSRQGPHIHV
DGAPGGIINFCANNYLGLSSHPEVIQAGLRTLKEFGAGLSSVRFICGTQSIHKDLEAKIA
RFHQREDAILYPSCFDANTGLFEALLTSEDAVLSDELNHASIIDGIRLCKAHKYRYRHLD
MADLEAKLQEAQKHRLRLVATDGAFSMDGDIAPLQEICRLASQYGALVFVDESHATGFLG
ATGRGTDELLGVMDQVTIINSTLGKALGGASGGYTTGPGALVSLLRQRARPYLFSNSLPP
AAVGCASKALDLLMESNAIVQSMAAKTLRFRSQMEAAGFTISGANHPICPVMLGDARLAL
NIADDMLKRGIFVIGFSYPVVPKGKARIRVQISAVHSEEDIDRCVEAFVEVGRLHGALP
|
| External Links |
|---|
| GenBank ID Protein
| AAI19871.1 |
| UniProtKB/Swiss-Prot ID
| Q0P5L8 |
| UniProtKB/Swiss-Prot Entry Name
| KBL_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC119870 |
| GeneCard ID
| GCAT |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
