| Identification |
|---|
| BMDB Protein ID
| BMDBP00405 |
| Secondary Accession Numbers
| None |
| Name
| 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| COQ5 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Coenzyme transport and metabolism |
| Specific Function
| Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). |
| Pathways
|
- Cofactor biosynthesis
- Ubiquinone Biosynthesis
|
| Reactions
|
| 2-Hexaprenyl-6-methoxy-1,4-benzoquinone + S-Adenosylmethionine → 2-Hexaprenyl-3-methyl-6-methoxy-1,4 benzoquinone + S-Adenosylhomocysteine |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 17 |
| Locus
| Not Available |
| SNPs
| COQ5 |
| Gene Sequence
|
>993 bp
ATGGCAGCCCCCAGGAGCTGGGCTCTATGGAGCTTCTGCGGCTGTGGGTGGTCGAGGGCA
GTGTCGGGCTGCAGGCTCCCCGGGCTTCGTAGCTCCTCGCCCAGGGGCCCCCTGGGTGCA
CGGCTCTTGTCCCAAGAGAAGGAGGCAACCGAAACGCACTTTGGGTTTGAGACTGTGTCG
GAAGAGGAGAAGGGGGGCAAAGTCTATCAGGTGTTTGAAAGTGTGGCCAAGAAGTATGAT
GTGATGAATGATATGATGAGTCTCGGTATCCATCGTGTTTGGAAGGATTTGCTGCTCTGG
AAGATGCGCCCGTTTCCTGGGACCCAGCTTCTGGATGTTGCTGGAGGCACAGGTGACATT
GCATTCCGGTTCCTTAATTATGTTCAGGCGCAGCATCAGAGAAAGCAGAAGAGGCAGCTA
AGGGCCCAACAAAATTTATCCTGGGAAGAAATTGCCAGAAAGTACCAGAATGAAGAGGAT
TCCTTGGGTGGTTCTCATGTCATGGTCTGTGACATCAACAAGGAGATGCTAAAGATTGGA
AAACAGAAAGCCCGTGCTCAAGGATACAAAGCTGGACTTGCCTGGATATTGGGAGATGCA
GAAGAACTGCCCTTCGACGATAACAAGTTTGATGTTTACACCATTGCCTTTGGGATCCGG
AACGTCACACACATTGATCAGGCACTACAGGAAGCCCACCGTGTCCTGAAACCAGGAGGA
AGGTTTCTCTGTCTGGAGTTCAGCCAAGTAAACAATCCCCTCCTATCCAGGCTCTATGAT
GTATATAGCTTCCAGGTCATTCCTGTCCTGGGAGAAGTCATTGCAGGAGATTGGAAGTCC
TACCAATACCTTGTAGAGAGTATCCGACAGTTCCCATCTCAGGAGGAATTCAAGGAGATG
ATAGAAGATGCAGGTTTTCAGAAGGTGACTTATGAAAATCTCACATCAGGCATTGTAGCC
ATTCACTCTGGTTTCAAACTTTATCTCCGTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 330 |
| Molecular Weight
| 37591.0 |
| Theoretical pI
| 8.2 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 66-86
- 93-113
- 160-180
- 193-213
- 226-248
- 261-281
- 295-315
- 349-369
|
| Protein Sequence
|
>Ubiquinone biosynthesis methyltransferase COQ5, mitochondrial
MAAPRSWALWSFCGCGWSRAVSGCRLPGLRSSSPRGPLGARLLSQEKEATETHFGFETVS
EEEKGGKVYQVFESVAKKYDVMNDMMSLGIHRVWKDLLLWKMRPFPGTQLLDVAGGTGDI
AFRFLNYVQAQHQRKQKRQLRAQQNLSWEEIARKYQNEEDSLGGSHVMVCDINKEMLKIG
KQKARAQGYKAGLAWILGDAEELPFDDNKFDVYTIAFGIRNVTHIDQALQEAHRVLKPGG
RFLCLEFSQVNNPLLSRLYDVYSFQVIPVLGEVIAGDWKSYQYLVESIRQFPSQEEFKEM
IEDAGFQKVTYENLTSGIVAIHSGFKLYLR
|
| External Links |
|---|
| GenBank ID Protein
| AAI20309.1 |
| UniProtKB/Swiss-Prot ID
| Q0P5A2 |
| UniProtKB/Swiss-Prot Entry Name
| COQ5_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC120308 |
| GeneCard ID
| COQ5 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
