| Identification |
|---|
| BMDB Protein ID
| BMDBP00422 |
| Secondary Accession Numbers
| None |
| Name
| Histone-lysine N-methyltransferase SETMAR |
| Synonyms
|
Not Available
|
| Gene Name
| SETMAR |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in histone-lysine N-methyltransferase activity |
| Specific Function
| Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically mediates dimethylation of H3 'Lys-36'. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 22 |
| Locus
| Not Available |
| SNPs
| SETMAR |
| Gene Sequence
|
>921 bp
ATGGCAACGTGTGAGGAGGTGCCTGAGGCCTTGAAGGGCCAGCTGGACGTTGCGCGTGGC
CTTGAAAATCTGCCTGTGAGCGCCTGGCCCCCAGGGGCGGAGCCTGAGCCCTTTCAGTAT
ACTCCTGATCATGTAGCTGGGCCTGGAGCAGATGCAGATCCCTCTCAAATAACCTTTCCT
GGATGTGCTTGTCTCAAAACTCCCTGCCTCCCTGGTACTTGTTCCTGTCTCCGTCATGAG
AATAACTATGATGATCGTTCATGCCTCAGAGATATAGGATCCGAAGCAAAGTGCACTGAG
CCAGTTTTCGAGTGCAATGTCCTGTGCCAGTGCAGCGAGCGCTGCAGGAACAGAGTGGTC
CAGTGGGGTCTGCAGTTCCACCTCCAGGTGTTCAAGACGGATCACAAAGGCTGGGGACTT
CGTACCCTGGACTTCATACCAAAAGGACGGTTTGTCTGTGAATATGCCGGTGAGGTGTTA
GGAATCTCTGAAGTGCAGAGAAGAGTTCAGTTACAAACAATACATGATTCGAATTACATT
ATAGCCATCAGGGAGCATGTCTATAATGGGCAGGTAATGGAAACATTTGTGGATCCTGCC
TCTATAGGAAATATTGGAAGATTCCTTAACCATTCTTGTGAGCCAAACCTGTTGATGATT
CCTGTCCGAATAGACTCGATGGTACCAAAGTTGGCACTTTTTGCAGCCAGAGACATTCTG
CCAGAAGAAGAACTCTCTTATGACTACTCAGGAAGATTTCTTAATCTAATGCATAGTGAA
GACAAAGAAAGGTTAGATAATGGGAAATTAAGGAAACCTTGTTATTGTGGTGCCAGATCA
TGTGCTGCGTTCCTGCCCTATGACAGCTCCCTGTACTGCCCCACAGAAAAGCCAGACACG
AGTGAGGAAGGAAGAGCATAG
|
| Protein Properties |
|---|
| Number of Residues
| 306 |
| Molecular Weight
| 34254.0 |
| Theoretical pI
| 4.99 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Histone-lysine N-methyltransferase SETMAR
MATCEEVPEALKGQLDVARGLENLPVSAWPPGAEPEPFQYTPDHVAGPGADADPSQITFP
GCACLKTPCLPGTCSCLRHENNYDDRSCLRDIGSEAKCTEPVFECNVLCQCSERCRNRVV
QWGLQFHLQVFKTDHKGWGLRTLDFIPKGRFVCEYAGEVLGISEVQRRVQLQTIHDSNYI
IAIREHVYNGQVMETFVDPASIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAARDIL
PEEELSYDYSGRFLNLMHSEDKERLDNGKLRKPCYCGARSCAAFLPYDSSLYCPTEKPDT
SEEGRA
|
| External Links |
|---|
| GenBank ID Protein
| AAI19875.1 |
| UniProtKB/Swiss-Prot ID
| Q0VD24 |
| UniProtKB/Swiss-Prot Entry Name
| SETMR_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC119874 |
| GeneCard ID
| SETMAR |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
