| Identification |
|---|
| BMDB Protein ID
| BMDBP00427 |
| Secondary Accession Numbers
| |
| Name
| Fumarylacetoacetase |
| Synonyms
|
Not Available
|
| Gene Name
| FAH |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Secondary metabolites biosynthesis, transport and catabolism |
| Specific Function
| Not Available |
| Pathways
|
- Acetoacetate and fumarate from L-phenylalanine: step 6/6
- Amino-acid degradation
- L-phenylalanine degradation
|
| Reactions
|
| 4-Fumarylacetoacetic acid + Water → Acetoacetic acid + Fumaric acid |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 21 |
| Locus
| Not Available |
| SNPs
| FAH |
| Gene Sequence
|
>1260 bp
ATGTCCTTCGTCCCGGTGGCCGAGGATTCTGACTTCCCCATCCACAACCTGCCCTACGGC
GTCTTCTCCACCCGAGGCAACCCAAGACCGAGGATTGGCGTGGCCATTGGGGACCAGATC
CTGGACCTCAGTGTCATCAAGCACCTCTTCACTGGGCCGATCCTCTCCGGACACCAGGAT
GTCTTCAATAAGCCAACTCTCAACAGCTTCATGGGCCTGGGTCAGGCTGCCTGGAAGGAG
GCTAGAGCATTCTTGCAGAACCTGCTGTCTGCCAGCCAAGCCAGGCTCAGAGATGACGTG
GAGCTTCGGCAGCGTGCCTTCACATCCCAGGCTTCCGCTACGATGTATCTTCCGGCCACC
ATAGGTGACTACACGGACTTCTATTCCTCTCGGCATCATGCCACCAATGTCGGGGTTATG
TTCAGGGGCAAGGAGAATGCACTGATGCCAAACTGGCTGCACCTGCCCGTGGGCTACCAC
GGGCGCGCTTCCTCCGTGGTGGTGTCTGGCACCCCGATCCGCAGGCCCCTGGGGCAGATG
CGACCCGACGACTCTAAGCCTCCCGTTTATGGTGCCTGCAAACTCCTGGACTTCGAGTTG
GAGATGGCTTTCTTTGTAGGCCCTGGGAACAAACTCGGAGAGCCAATCCCCATTTCCAAG
GCCCACGAGCACATTTTTGGAATGGTCCTTATGAACGACTGGAGTGCTCGAGACATCCAG
AAATGGGAGTACGTCCCACTTGGGCCGTTCCTTGGGAAGAGTTTTGGAACCACCATCTCT
CCGTGGGTGGTGCCCATGGATGCCCTCATGCCCTTTGCTGTGTCCAACCCGGAGCAGGAC
CCCAAGCCCCTGCCGTATCTCTGCCATGACCAGCCCTACACATTCGACATCAACCTCTCT
GTTGCCCTGAAAGGAGAAGGAATGAGCCAGGCAGCTACCATATGCAGGTCTAATTTTAAG
TACATGTACTGGACAATGCTGCAGCAGCTCACCCACCACTCTGTCAATGGCTGCAACCTG
CAGCCGGGCGACCTCTTGGCTTCTGGAACCATCAGCGGGCCGGAGCCAGAGAGCTTCGGC
TGCATGCTGGAGCTGTCGTGGAAGGGCACAAGGGCCGTAGAGCTGGGGAATGGCCAGACC
AGGAAGTTCCTGCTGGATGGGGATGAAGTCATCATGACAGGGCACTGCCAGGGGGATGGG
TACCGCATTGGCTTCGGCCAGTGTGCGGGAAAAGTGCTGCCTGCCCTGTCGTTCGCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 419 |
| Molecular Weight
| 46156.0 |
| Theoretical pI
| 6.99 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Fumarylacetoacetase
MSFVPVAEDSDFPIHNLPYGVFSTRGNPRPRIGVAIGDQILDLSVIKHLFTGPILSGHQD
VFNKPTLNSFMGLGQAAWKEARAFLQNLLSASQARLRDDVELRQRAFTSQASATMYLPAT
IGDYTDFYSSRHHATNVGVMFRGKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPLGQM
RPDDSKPPVYGACKLLDFELEMAFFVGPGNKLGEPIPISKAHEHIFGMVLMNDWSARDIQ
KWEYVPLGPFLGKSFGTTISPWVVPMDALMPFAVSNPEQDPKPLPYLCHDQPYTFDINLS
VALKGEGMSQAATICRSNFKYMYWTMLQQLTHHSVNGCNLQPGDLLASGTISGPEPESFG
CMLELSWKGTRAVELGNGQTRKFLLDGDEVIMTGHCQGDGYRIGFGQCAGKVLPALSFA
|
| External Links |
|---|
| GenBank ID Protein
| AAI42488.1 |
| UniProtKB/Swiss-Prot ID
| A5PKH3 |
| UniProtKB/Swiss-Prot Entry Name
| FAAA_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC142487 |
| GeneCard ID
| FAH |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
