| Identification |
|---|
| BMDB Protein ID
| BMDBP00430 |
| Secondary Accession Numbers
| None |
| Name
| Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha |
| Synonyms
|
Not Available
|
| Gene Name
| PDE6A |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in 3',5'-cyclic-GMP phosphodiesterase activity |
| Specific Function
| This protein participates in processes of transmission and amplification of the visual signal. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 7 |
| Locus
| Not Available |
| SNPs
| PDE6A |
| Gene Sequence
|
>2580 bp
ATGGGCGAGGTGACGGCAGAGGAAGTAGAGAAGTTTCTGGACTCAAATGTCAGCTTTGCC
AAACAGTACTACAACCTGCGCTACCGGGCCAAGGTCATCTCAGACCTGCTGGGACCCAGG
GAGGCGGCCGTGGACTTCAGCAACTACCATGCGCTGAACAGCGTGGAAGAGAGTGAAATT
ATCTTCGACCTCCTGCGGGACTTTCAGGACAACCTGCAGGCCGAGAAGTGCGTCTTCAAT
GTCATGAAGAAGTTGTGCTTCCTGCTGCAGGCCGACCGCATGAGCCTATTCATGTACAGG
GCCCGGAACGGCATCGCAGAGCTGGCCACCCGGCTCTTCAACGTCCACAAGGATGCTGTG
CTCGAGGAGTGCCTGGTGGCGCCTGACTCGGAGATCGTGTTCCCCCTGGACATGGGAGTG
GTGGGCCATGTTGCGCTCTCTAAAAAGATCGTCAACGTCCCCAACACAGAGGAGGATGAA
CATTTCTGTGACTTTGTGGACACCCTCACAGAGTACCAGACTAAGAACATCTTGGCTTCT
CCCATAATGAATGGGAAGGATGTGGTGGCCATAATCATGGCTGTGAATAAAGTGGATGGG
CCCCACTTCACCGAGAATGATGAAGAGATTCTTCTCAAGTACCTCAATTTTGCAAATCTA
ATCATGAAGGTGTTCCACCTGAGTTACCTGCACAACTGTGAGACTCGGCGTGGCCAGATA
CTGTTGTGGTCTGGGAGCAAAGTCTTTGAAGAGCTTACAGACATTGAGAGGCAGTTCCAC
AAAGCCCTGTACACAGTCCGCGCCTTCCTCAACTGTGACAGATACTCTGTGGGGCTCTTA
GACATGACCAAACAGAAGGAATTTTTTGATGTGTGGCCAGTCCTGATGGGGGAGGCTCCA
CCCTACGCTGGTCCCAGGACTCCGGATGGAAGGGAAATCAACTTTTACAAGGTCATTGAC
TACATCCTGCATGGCAAAGAAGACATCAAAGTCATCCCGAATCCTCCTCCAGACCACTGG
GCTTTAGTGAGCGGTCTCCCCACTTATGTTGCCCAAAATGGCCTGATTTGCAACATCATG
AACGCGCCTTCAGAGGACTTTTTTGCATTCCAGAAAGAGCCTCTGGATGAGTCTGGATGG
ATGATTAAAAATGTCCTTTCTATGCCAATTGTGAACAAGAAGGAGGAAATTGTTGGGGTG
GCCACGTTTTACAATCGCAAAGATGGAAAACCCTTTGATGAAATGGATGAGACCCTCATG
GAGTCTTTGGCCCAGTTCCTGGGCTGGTCTGTCTTAAATCCTGACACTTATGAGTTGATG
AACAAACTTGAAAACAGGAAGGATATTTTCCAAGACATGGTGAAATACCACGTGAAGTGT
GACAATGAAGAAATCCAGACAATCTTGAAAACCAGAGAGGTGTATGGGAAGGAGCCGTGG
GAATGCGAGGAAGAAGAACTGGCTGAGATCCTGCAAGGAGAGCTGCCAGATGCAGACAAA
TATGAAATTAATAAATTCCACTTCAGCGACCTGCCCCTGACGGAACTGGAGCTGGTGAAA
TGTGGAATTCAGATGTACTATGAGCTCAAAGTGGTGGATAAATTTCACATTCCTCAGGAG
GCCCTGGTGCGGTTCATGTATTCCCTGAGCAAGGGCTACCGCAGGATCACCTACCACAAC
TGGCGGCACGGCTTCAACGTGGGGCAGACCATGTTCTCCTTGCTGGTGACCGGAAAGCTG
AAGCGATACTTCACAGACCTGGAGGCCTTGGCCATGGTCACCGCCGCCTTCTGCCATGAC
ATTGACCACAGAGGCACTAACAATCTCTACCAGATGAAATCCCAGAACCCACTGGCCAAG
CTCCATGGGTCCTCCATCTTGGAAAGACACCACTTGGAGTTTGGTAAAACACTGTTGAGA
GATGAGAGCCTAAATATCTTTCAGAACCTCAATCGCAGGCAGCACGAGCATGCAATCCAC
ATGATGGACATCGCGATCATTGCTACAGACCTTGCCTTGTATTGCAAGAAAAGGACGATG
TTCCAAAAGATCGTGGATCAGTCTAAGACATACGAGACTCAGCAGGAGTGGACACAGTAC
ATGATGCTGGATCAGACACGGAAGGAAATTGTCATGGCCATGATGATGACCGCCTGTGAT
CTCTCAGCCATCACCAAGCCTTGGGAGGTGCAGAGCAAGGTGGCTCTGCTGGTTGCTGCT
GAATTCTGGGAACAAGGTGACCTGGAGCGCACGGTGCTGCAACAGAATCCCATTCCCATG
ATGGACAGAAACAAGGCGGATGAACTCCCTAAGCTTCAGGTCGGCTTCATCGACTTTGTT
TGCACCTTTGTCTACAAGGAATTCTCCCGTTTCCACGAGGAGATCACTCCCATGCTAGAT
GGGATTACCAACAACCGCAAGGAGTGGAAAGCGCTTGCTGATGAGTATGAGACCAAGATG
AAGGGGCTGGAGGAGGAGAAGCAGAAACAGCAGGCAGCCAACCAAGCAGCCGCAGGAAGT
CAACACGGCGGAAAGCAACCTGGGGGCGGGCCTGCATCCAAGTCTTGCTGCGTCCAATAG
|
| Protein Properties |
|---|
| Number of Residues
| 859 |
| Molecular Weight
| 99341.0 |
| Theoretical pI
| 5.2 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha
MGEVTAEEVEKFLDSNVSFAKQYYNLRYRAKVISDLLGPREAAVDFSNYHALNSVEESEI
IFDLLRDFQDNLQAEKCVFNVMKKLCFLLQADRMSLFMYRARNGIAELATRLFNVHKDAV
LEECLVAPDSEIVFPLDMGVVGHVALSKKIVNVPNTEEDEHFCDFVDTLTEYQTKNILAS
PIMNGKDVVAIIMVVNKVDGPHFTENDEEILLKYLNFANLIMKVFHLSYLHNCETRRGQI
LLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEAP
PYAGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPPDHWALVSGLPTYVAQNGLICNIM
NAPSEDFFAFQKEPLDESGWMIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLM
ESLTQFLGWSVLNPDTYELMNKLENRKDIFQDMVKYHVKCDNEEIQTILKTREVYGKEPW
ECEEEELAEILQGELPDADKYEINKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQE
ALVRFMYSLSKGYRRITYHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHD
IDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIH
MMDIAIIATDLALYFKKRTMFQKIVDQSKTYETQQEWTQYMMLDQTRKEIVMAMMMTACD
LSAITKPWEVQSKVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFV
CTFVYKEFSRFHEEITPMLDGITNNRKEWKALADEYETKMKGLEEEKQKQQAANQAAAGS
QHGGKQPGGGPASKSCCVQ
|
| External Links |
|---|
| GenBank ID Protein
| CAA31243.1 |
| UniProtKB/Swiss-Prot ID
| P11541 |
| UniProtKB/Swiss-Prot Entry Name
| PDE6A_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| X12756 |
| GeneCard ID
| PDE6A |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
