| Identification |
|---|
| BMDB Protein ID
| BMDBP00481 |
| Secondary Accession Numbers
| None |
| Name
| Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| C1GALT1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in glycoprotein-N-acetylgalactosamine 3-beta-g |
| Specific Function
| Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development (By similarity). |
| Pathways
|
- Protein glycosylation
- Protein modification
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 4 |
| Locus
| Not Available |
| SNPs
| C1GALT1 |
| Gene Sequence
|
>1107 bp
ATGGCCTCTAAATCTTGGCTGAATATTTTAACCTTCCTTTGTGGATCAGCAGTCGGATTT
GTTTTATGCTCTCAGCTACTTAGTATTTTGTTCGAAGAACAGAAGGACATCCAGCCTAGT
ATTCTTCATAATGATCCTCACGCTAGGCATTCAGATGACAATGAACAGAATCATCTAGAA
GGACAGATGAACTTCGATGCAGATGCCAGCCAACATAAAGATGAGAACACTGACATCGCT
GATAAGCTCTATCAGAAGGTTAAAATTCTTTGCTGGGTAATGACAGGGCCTCAAAATCTA
GAGAAAAAGGCTAAACATGTCAAAGCCACATGGGCCCAGCGTTGTAATAAAGTGTTGTTT
ATGAGTTCAGAAGAAAACAAGGACTTCCCTGCTGTGGGATTAAAAACCAGAGAAGGCAGA
GACCAACTGTACTGGAAAACAATTAAAGCCTTTCAGTATGTTCATGATCATTATTTAGAA
GATGCTGATTGGTTTATGAAAGCAGATGATGATACTTACGTTATACTAGATAACTTGAGA
TGGCTTCTCTCAAAATACAACCCTGAAGAACCCATTTACTTTGGGAGAAGATTTAAGCCC
TATGTAAAGCAGGGCTACATGAGTGGAGGAGCAGGATATGTACTGAGCAAAGAAGCTTTG
AAGAGATTTGTTGAAGCATTTAAAACAGACAAATGTACACACAGTTCCTCAATCGAAGAT
TTAGCACTGGGGAGATGCATGGAAATTATAAATGTAGAAGCGGGAGATTCCAGAGACACC
ACTGGAAAAGAAACTTTTCATCCTTTTGTACCAGAACACCACTTAATCAAGGGTTATCTG
CCGAGAACCTTTTGGTACTGGAATTATAACTATTATCCTCCTGTAGAGGGTCCTGGTTGC
TGTTCCGATCTTGCAGTTTCTTTTCACTATGTTGATCCTACAACTATGTATGAGTTAGAA
TACCTCGTTTATCATCTTCGTCCGTATGGTTATTTATACAGATATCAACCTGCCTTACCT
GAGAAGATGCTAAAGGAAGTAAGTCAGATATACAAAAATGAAGACACAAACGTAAATCAG
GAGCCCTTGAAAGAAAAACATAAATGA
|
| Protein Properties |
|---|
| Number of Residues
| 368 |
| Molecular Weight
| 43041.0 |
| Theoretical pI
| 6.45 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
MASKSWLNILTFLCGSAVGFVLCSQLLSILFEEQKDIQPSILHNDPHARHSDDNEQNHLE
GQMNFDADASQHKDENTDIADKLYQKVKILCWVMTGPQNLEKKAKHVKATWAQRCNKVLF
MSSEENKDFPAVGLKTREGRDQLYWKTIKAFQYVHDHYLEDADWFMKADDDTYVILDNLR
WLLSKYNPEEPIYFGRRFKPYVKQGYMSGGAGYVLSKEALKRFVEAFKTDKCTHSSSIED
LALGRCMEIINVEAGDSRDTTGKETFHPFVPEHHLIKGYLPRTFWYWNYNYYPPVEGPGC
CSDLAVSFHYVDPTTMYELEYLVYHLRPYGYLYRYQPALPEKMLKEVSQIYKNEDTNVNQ
EPLKEKHK
|
| External Links |
|---|
| GenBank ID Protein
| AAI20300.1 |
| UniProtKB/Swiss-Prot ID
| Q0VC84 |
| UniProtKB/Swiss-Prot Entry Name
| C1GLT_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC120299 |
| GeneCard ID
| C1GALT1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
