| Identification |
|---|
| BMDB Protein ID
| BMDBP00482 |
| Secondary Accession Numbers
| |
| Name
| Ribose-phosphate pyrophosphokinase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| PRPS1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Nucleotide transport and metabolism |
| Specific Function
| Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. |
| Pathways
|
- 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis
- 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1
- Metabolic intermediate biosynthesis
|
| Reactions
|
| D-Ribose 5-phosphate + Adenosine triphosphate → Phosphoribosyl pyrophosphate + Adenosine monophosphate |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| X |
| Locus
| Not Available |
| SNPs
| PRPS1 |
| Gene Sequence
|
>957 bp
ATGCCGAATATCAAAATCTTCAGCGGCAGCTCCCACCAGGACCTATCCCAGAAGATTGCC
GACCGCCTGGGCCTGGAACTGGGCAAGGTGGTGACTAAGAAATTCAGCAACCAGGAGACC
TGTGTGGAAATCGGAGAAAGTGTTCGTGGAGAAGATGTCTACATTGTTCAGAGTGGCTGC
GGTGAAATCAATGACAATCTCATGGAACTTTTGATTATGATTAATGCCTGCAAGATTGCT
TCAGCCAGCCGGGTTACTGCAGTCATCCCGTGCTTCCCTTATGCCCGGCAGGATAAGAAG
GATAAGAGCCGGGCTCCAATCTCAGCCAAGCTGGTTGCAAATATGCTGTCTGTAGCAGGC
GCGGATCATATTATCACCATGGACCTTCATGCTTCTCAAATTCAGGGCTTTTTTGATATC
CCAGTCGACAATTTGTATGCAGAGCCAGCGGTCCTCAAGTGGATAAGGGAGAACATCTCT
GAGTGGAGGAACTGCACAATTGTCTCACCTGATGCTGGAGGAGCAAAGAGAGTGACTTCC
ATCGCAGACCGGTTGAATGTGGACTTTGCCTTGATTCACAAAGAACGGAAGAAGGCCAAT
GAAGTGGACCGCATGGTGCTCGTAGGAGACGTGAAGGACCGTGTGGCCATCCTCGTGGAT
GACATGGCTGACACTTGTGGCACAATCTGCCATGCAGCTGACAAACTTCTCTCAGCTGGA
GCCACCAGGGTTTATGCTATCCTGACTCATGGAATCTTTTCTGGCCCAGCCATTTCTCGT
ATTAATAATGCATGCTTTGAAGCAGTAGTAGTCACCAATACCATACCTCAGGAGGATAAG
ATGAAGCATTGCTCCAAAATACAGGTGATTGACATCTCCATGATCCTCGCAGAAGCCATC
AGGAGAACTCACAATGGAGAATCCGTCTCCTATCTGTTCAGCCATGTCCCTTTATAA
|
| Protein Properties |
|---|
| Number of Residues
| 318 |
| Molecular Weight
| 34834.0 |
| Theoretical pI
| 6.98 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Ribose-phosphate pyrophosphokinase 1
MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGC
GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG
ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTS
IADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG
ATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAI
RRTHNGESVSYLFSHVPL
|
| External Links |
|---|
| GenBank ID Protein
| AAI13301.1 |
| UniProtKB/Swiss-Prot ID
| Q2HJ58 |
| UniProtKB/Swiss-Prot Entry Name
| PRPS1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC113300 |
| GeneCard ID
| PRPS1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
