| Identification |
|---|
| BMDB Protein ID
| BMDBP00518 |
| Secondary Accession Numbers
| None |
| Name
| Nucleoside diphosphate kinase A 2 |
| Synonyms
|
Not Available
|
| Gene Name
| NME1-2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Nucleotide transport and metabolism |
| Specific Function
| Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 19 |
| Locus
| Not Available |
| SNPs
| NME1-2 |
| Gene Sequence
|
>459 bp
ATGGCCAACAGCGAGCGCACCTTCATTGCCATCAAGCCCGATGGAGTCCAGCGAGGCCTC
ATGGGAGAAATAATCAAGCGTTTTGAGCAAAAGGGATTCCGTCTTGTTGCCATGAAATTC
ATGCGGGCTTCTGAAGACCTTCTCAAGGAGCACTATATTGACCTGAAGGACCGTCCATTC
TTTGCTGGCCTGGTGAAATACATGCACTCAGGGCCCGTGGTTGCCATGGTCTGGGAGGGA
CTGAATGTTGTGAAGACAGGTCGAGTGATGCTTGGGGAGACTAACCCTGCGGACTCCAAG
CCTGGGACCATCCGTGGTGACTTTTGCATCCAAGTTGGCAGGAACATTATCCATGGCAGT
GATTCCGTGGAGAGTGCAGAGAAGGAGATTGCCTTGTGGTTTCGCCCTGAGGAACTGGTG
AATTACAAGAGCTGTGCTCAGAACTGGATCTACGAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 152 |
| Molecular Weight
| 17298.0 |
| Theoretical pI
| 8.21 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Nucleoside diphosphate kinase A 2
MANSERTFIAIKPDGVQRGLMGEIIKRFEQKGFRLVAMKFMRASEDLLKEHYIDLKDRPF
FAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS
DSVESAEKEIALWFRPEELVNYKSCAQNWIYE
|
| External Links |
|---|
| GenBank ID Protein
| CAA63533.1 |
| UniProtKB/Swiss-Prot ID
| P52175 |
| UniProtKB/Swiss-Prot Entry Name
| NDKA2_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| X92957 |
| GeneCard ID
| NME1-2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
