<?xml version="1.0" encoding="UTF-8"?>
<protein>
  <version>1.0</version>
  <creation_date>2018-05-07 22:22:47 UTC</creation_date>
  <update_date>2020-05-20 21:03:01 UTC</update_date>
  <accession>BMDBP00525</accession>
  <secondary_accessions>
  </secondary_accessions>
  <protein_type>Enzyme</protein_type>
  <synonyms>
  </synonyms>
  <gene_name>ADSS2</gene_name>
  <general_function>Nucleotide transport and metabolism</general_function>
  <specific_function>Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</specific_function>
  <pathways>
    <pathway>
      <name>AMP biosynthesis via de novo pathway</name>
      <smpdb_id/>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>AMP from IMP: step 1/2</name>
      <smpdb_id/>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>Purine Metabolism</name>
      <smpdb_id>SMP0087239</smpdb_id>
      <kegg_map_id/>
    </pathway>
  </pathways>
  <metabolite_associations>
    <metabolite>
      <accession>BMDB0000191</accession>
      <name>L-Aspartic acid</name>
    </metabolite>
    <metabolite>
      <accession>BMDB0000536</accession>
      <name>Adenylsuccinic acid</name>
    </metabolite>
    <metabolite>
      <accession>BMDB0000547</accession>
      <name>Magnesium</name>
    </metabolite>
    <metabolite>
      <accession>BMDB0001273</accession>
      <name>Guanosine triphosphate</name>
    </metabolite>
    <metabolite>
      <accession>BMDB0000175</accession>
      <name>Inosinic acid</name>
    </metabolite>
    <metabolite>
      <accession>BMDB0001201</accession>
      <name>Guanosine diphosphate</name>
    </metabolite>
    <metabolite>
      <accession>BMDB0000973</accession>
      <name>Hydrogen phosphate</name>
    </metabolite>
  </metabolite_associations>
  <go_classifications>
  </go_classifications>
  <subcellular_locations>
  </subcellular_locations>
  <gene_properties>
    <chromosome_location>16</chromosome_location>
    <locus/>
    <gene_sequence/>
  </gene_properties>
  <protein_properties>
    <residue_number>456</residue_number>
    <molecular_weight>50156.0</molecular_weight>
    <theoretical_pi>6.72</theoretical_pi>
    <pfams>
    </pfams>
    <transmembrane_regions>
    </transmembrane_regions>
    <signal_regions>
      <region>None</region>
    </signal_regions>
    <polypeptide_sequence>&gt;Adenylosuccinate synthetase isozyme 2
MAFAETNPATSSLPNGDCGRPRTRPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRC
QGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGL
EGWEKRLIISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLR
MCDLVSDFGGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMERIKPMVRDGVYFLYE
ALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAY
TTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALAL
TKLDILDMFTEIKVGVAYKLDGEIIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKE
LPINAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF</polypeptide_sequence>
  </protein_properties>
  <genbank_protein_id>AAI51542.1</genbank_protein_id>
  <uniprot_id>A7MBG0</uniprot_id>
  <uniprot_name>PURA2_BOVIN</uniprot_name>
  <pdb_ids>
  </pdb_ids>
  <genbank_gene_id>BC151541</genbank_gene_id>
  <genecard_id>ADSS2</genecard_id>
  <geneatlas_id/>
  <general_references>
  </general_references>
  <metabolite_references>
  </metabolite_references>
</protein>
