1.0 2018-05-07 22:22:53 UTC 2020-05-20 21:10:54 UTC BMDBP00546 Enzyme DIO2 Involved in selenium binding Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development. BMDB0000248 Thyroxine BMDB0001349 Selenium BMDB0003288 Selenocysteine BMDB0012238 Iodide 10 >810 bp ATGGGCATCCTCAGCGTAGACTTGCTGATCACACTGCAGATTCTGCCAGTTTTTTTCTCC AACTGCCTCTTCCTGGCGCTCTATGACTCGGTCATTCTCCTCAAGCACGTGGTGCTGCTG CTGAGCCGCTCCAAGTCCACTCGCGGGCAGTGGAGGCGCATGCTGACCTCAGAAGGAATG CGCTGCATCTGGAAAAGCTTCCTCCTCGACGCCTACAAACAGGTGAAACTGGGTGAAGAT GCCCCCAATTCCAGCGTGGTGCATGTCTCCAGTCCGGAAGGAGGTGACACCAGTGGAAAT GGTGCCCAGGAGAAAACAGTGGATGGAACTGAATGCCACCTTCTGGACTTTGCCAGCCCT GAGCGCCCACTGGTGGTCAACTTCGGCTCGGCCACTTGACCTCCTTTCACTAACCAGCTG CCAGCCTTCAGCAAACTGGTGGAAGAGTTCTCATCCGTGGCTGACTTCCTGTTGGTCTAC ATTGATGAGGCTCATCCTTCAGATGGTTGGGCAGTGCCTGGGGATTCTTCTTTGTTTTTC GAGGTGAAGAAGCACCGGAACCAGGAAGACCGATGCGCAGCAGCCCACCAGCTCCTGGAG CGTTTCTCCTTGCCGCCCCAGTGCCGAGTTGTGGCTGACCGCATGGACAATAATGCCAAC GTTGCTTATGGGGTAGCCTTTGAACGTGTGTGCATCGTGCAGAGACAGAAAATTGCTTAT CTGGGAGGAAAGGGCCCCTTCTTTTACAACCTGCAAGAAGTCCGGCGTTGGCTGGAGAAG AATTTCAGCAAGAGATGAAAGCTAGATTAG 269 30303.0 7.47 10-34 None >Type II iodothyronine deiodinase MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGQWRRMLTSEGM RCIWKSFLLDAYKQVKLGEDAPNSSVVHVSSPEGGDTSGNGAQEKTVDGTECHLLDFASP ERPLVVNFGSATUPPFTNQLPAFSKLVEEFSSVADFLLVYIDEAHPSDGWAVPGDSSLFF EVKKHRNQEDRCAAAHQLLERFSLPPQCRVVADRMDNNANVAYGVAFERVCIVQRQKIAY LGGKGPFFYNLQEVRRWLEKNFSKRUKLD AAW51123.1 Q5I3B2 IOD2_BOVIN AY858551 DIO2