| Identification |
|---|
| BMDB Protein ID
| BMDBP00568 |
| Secondary Accession Numbers
| None |
| Name
| Aspartyl/asparaginyl beta-hydroxylase |
| Synonyms
|
Not Available
|
| Gene Name
| ASPH |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Posttranslational modification, protein turnover, chaperones |
| Specific Function
| Specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 14 |
| Locus
| Not Available |
| SNPs
| ASPH |
| Gene Sequence
|
>2265 bp
ATGGCCCCGCGCAAGAATGCCAAGGGCGGCGGCGGCAACAGCAGCAGCAGCAGCTCTGGC
AGTCCGACCGGCTGCACCAGCGGCGGCAGCAGCAGCCCCGGGGCCCGGAGAGAGACGAAA
CAGGGAGGACTCAAGAATGGGAGGAAAGGAGGACTTTCTGGAAGTTCATTTTTCACATGG
TTTATGGTCATTGCACTGCTCGGAGTCTGGACATCAGTAGCTGTGGTCTGGTTTGATCTT
GTTGATTATGAAGAAGTGTTAGCCAAAGCAAAGGACTTCCGTTATAACTTGTCAGAGGTA
CTTCAAGGAAAACTTGGAATCTATGATGCTGATGGTGATGGAGATTTTGATGTGGATGAT
GCCAAAGTTTTATTAGGCCTTAAAGAAAAACCTGCTCCAAAGCCAACAGTGCCACCAGAA
GAGGCAGACATGTACCCTTGGCTGGAAGATCAGGTTCTGGAGAGCCCAGGACGTCAGAAT
ATTGAAGATGAAGTATATGAACAAGTTCAGTCACTTGATGAAACAGTATACTCAGAACCT
GGAGAGAACCTGCCCCAAGAACCAGAAGGACCAGCAGAAGAGCTGCAGCCCGACGACCAT
GTCTTTGTAGGAAGTGATGCAGATGACAGATACGAACCCATGGGAACTGGAGCCGTTCAT
GAAGAAACTGAAGATAGCTACCATATAGAAGAGACAGCTTCGCCAGCCTACAGTCAAGAT
ATGGAAGACATGATGTATGAGCAGGAAAATCCAGATTCCAGTGAACCAGTAGTAGTAGAT
GATGCTGAAAGAACATACCAAGAAACAGATGATGTCACCTACCGAGACTATGATGAACAA
GATCATGCTGTAGATAATTCAAACACAATTTTAGAAGAACCGCACATGCCCCCTGCAGAG
GAACAGCAAGAAGTACCACCAGAAACAAATAAGAAAGCAGATGAGCCAGGAAAAAAAGGA
AAAGTGAAGAAAAAGAAGCCTAAACTATTAAATAAATTTGATAAGACTATTAAAGCTGAG
CTCGATGCTGCAGAAAAACTCCGTAAAAGGGGAAAAATTGAGGAAGCAGTGAATGCATTT
GAAGAACTGGTTCGCAAGTACCCTCAGAGTCCAGGAGCTCGGTATGGGAAAGCACAGTGT
GAAGATGATTTGGCTGAGAAGAGAAGGAGCAATGAGATCCTGCGCAGGGCCATCGAGACC
TACCAGGAGGCGGCCAGTCTGCCTGATGCCCCCACAGACTTGGTGAAGCTGAGCCTGAAG
CGGAGGTCAGACAGACAGCAGTTTCTAGGTCACATGAGAGGATCCTTGCTTACTCTTCAG
AAATTAGTTCAACTATTTCCTGATGATACTGCCTTAAAGAATGACCTTGGAGTTGGATAC
CTCTTGATAGGTGACAATGACAGTGCCAAGAAGGTCTATGAAGAGGTTCTGAGCGTGACA
CCCAATGATGGTTTTGCTAAAGTGCATTATGGCTTTATCCTGAAGGCACAGAACAAGATT
GCTGAGAGCATCCCCTATCTGAAGGAAGGAATAGAATCTGGGGATCCTGGTACTGATGAT
GGGAGATTTTATTTTCACCTGGGGGACGCCATGCAGAGAGTTGGAAACAAAGAGGCATAT
CGGTGGTACGAGCTGGGGCACCAGAGGGGCCACTTTGCCTCCGTGTGGCAGCGCTCACTG
TACAACGTGCAGGGATTGAAAGCCCAGCCGTGGTGGACCCCCAAAGAGACCGGCTACACC
GAGTTAGTGAAGTCCTTAGAAAGAAACTGGAAGTTAATCAGAGATGAAGGCCTTGCAGCA
ATGGATAGAACCCATGGCCTCTTCCTGCCTGAAGATGAGAACCTGAGGGAAAAGGGTGAC
TGGAGTCAGTTTACGCTGTGGCAGCAAGGAAGAAAAAATGAAAATGCCTGTAAAGGAGCT
CCTAAGACCTGTTCTTTACTAGATAAATTCCCTGAGACAACAGGATGCCGAAGAGGACAG
ATCAAATATTCCATCATGCACCCGGGAACCCACGTGTGGCCGCACACGGGACCCACGAAC
TGTAGGCTCCGAATGCACCTGGGCTTGGTGATTCCCAAGGAAGGCTGCAAGATCCGATGC
GCCAACGAGACCAGGACGTGGGAAGAAGGCAAGGTGCTCATCTTTGACGACTCCTTTGAA
CACGAGGTGTGGCAGGATGCCGCGTCTTTCCGGCTCATCTTCATTGTGGATGTGTGGCAC
CCTGAGCTGACACCCCATCAGAGACGCAGCCTTCCTGCAATTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 754 |
| Molecular Weight
| 84999.0 |
| Theoretical pI
| 4.81 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Aspartyl/asparaginyl beta-hydroxylase
MAPRKNAKGGGGNSSSSSSGSPTGCTSGGSSSPGARRETKQGGLKNGRKGGLSGSSFFTW
FMVIALLGVWTSVAVVWFDLVDYEEVLAKAKDFRYNLSEVLQGKLGIYDADGDGDFDVDD
AKVLLGLKEKPAPKPTVPPEEADMYPWLEDQVLESPGRQNIEDEVYEQVQSLDETVYSEP
GENLPQEPEGPAEELQPDDHVFVGSDADDRYEPMGTGAVHEETEDSYHIEETASPAYSQD
MEDMMYEQENPDSSEPVVVDDAERTYQETDDVTYRDYDEQDHAVDNSNTILEEPHMPPAE
EQQEVPPETNKKADEPGKKGKVKKKKPKLLNKFDKTIKAELDAAEKLRKRGKIEEAVNAF
EELVRKYPQSPGARYGKAQCEDDLAEKRRSNEILRRAIETYQEAASLPDAPTDLVKLSLK
RRSDRQQFLGHMRGSLLTLQKLVQLFPDDTALKNDLGVGYLLIGDNDSAKKVYEEVLSVT
PNDGFAKVHYGFILKAQNKIAESIPYLKEGIESGDPGTDDGRFYFHLGDAMQRVGNKEAY
RWYELGHQRGHFASVWQRSLYNVQGLKAQPWWTPKETGYTELVKSLERNWKLIRDEGLAA
MDRTHGLFLPEDENLREKGDWSQFTLWQQGRKNENACKGAPKTCSLLDKFPETTGCRRGQ
IKYSIMHPGTHVWPHTGPTNCRLRMHLGLVIPKEGCKIRCANETRTWEEGKVLIFDDSFE
HEVWQDAASFRLIFIVDVWHPELTPHQRRSLPAI
|
| External Links |
|---|
| GenBank ID Protein
| AAA03563.1 |
| UniProtKB/Swiss-Prot ID
| Q28056 |
| UniProtKB/Swiss-Prot Entry Name
| ASPH_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| M91213 |
| GeneCard ID
| ASPH |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
