| Identification |
|---|
| BMDB Protein ID
| BMDBP00585 |
| Secondary Accession Numbers
| None |
| Name
| Flavin reductase (NADPH) |
| Synonyms
|
Not Available
|
| Gene Name
| BLVRB |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Cell wall/membrane/envelope biogenesis |
| Specific Function
| Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 18 |
| Locus
| Not Available |
| SNPs
| BLVRB |
| Gene Sequence
|
>621 bp
ATGGTCGTCAAGAAGATTGCCCTTTTCGGCGCCACCGGCAACACCGGGCTCACCACGCTG
GCGCAGGCGGTGCAAGCAGGCTATGAGGTGACGGTGCTGGTGCGGGACCCCTCCAGGCTG
CCCTCAGAGGGGCCCCAGCCGGCCCACGTGGTGGTGGGTGACGTCCGGCAGCCGGCCGAT
GTGGACAAGACCGTGGCTGGGCAGGACGCTGTCATCGTGCTGCTGGGCACCCGCAATGAC
CTCAGTCCTACCACAGTGATGTCCGAGGGTGCCCAGAACATTGTGGCAGCCATGAAGGCC
CATGGCGTGGACAAGGTCGTGGCCTGCACCTCGGCCTTCCTACTGTGGGACCCTTCCAAG
GTGCCCCCAAGACTGCAGGATGTGACTGATGACCATATCCGGATGCACAAGGTACTGCAG
CAGTCGGGCCTGAAGTACGTGGCCGTGATGCCACCACATATAGGAGACCACCCATTGACT
GGGGCCTACACAGTGACCCTGGATGGACGAGGGCCCTCGAGAGTCATCTCCAAACATGAC
CTGGGCCACTTCATGCTGCACTGCCTCACCACCGATAAGTACGACGGGCACACCACCTAC
CCCTCCCATGTGTATGAATAG
|
| Protein Properties |
|---|
| Number of Residues
| 206 |
| Molecular Weight
| 22132.0 |
| Theoretical pI
| 7.13 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Flavin reductase
MVVKKIALFGATGNTGLTTLAQAVQAGYEVTVLVRDPSRLPSEGPQPAHVVVGDVRQPAD
VDKTVAGQDAVIVLLGTRNDLSPTTVMSEGAQNIVAAMKAHGVDKVVACTSAFLLWDPSK
VPPRLQDVTDDHIRMHKVLQQSGLKYVAVMPPHIGDHPLTGAYTVTLDGRGPSRVISKHD
LGHFMLHCLTTDKYDGHTTYPSHVYE
|
| External Links |
|---|
| GenBank ID Protein
| AAC37323.1 |
| UniProtKB/Swiss-Prot ID
| P52556 |
| UniProtKB/Swiss-Prot Entry Name
| BLVRB_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| L35045 |
| GeneCard ID
| BLVRB |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
