| Identification |
|---|
| BMDB Protein ID
| BMDBP00593 |
| Secondary Accession Numbers
| None |
| Name
| 4-trimethylaminobutyraldehyde dehydrogenase |
| Synonyms
|
Not Available
|
| Gene Name
| ALDH9A1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. |
| Pathways
|
- Amine and polyamine biosynthesis
- Carnitine biosynthesis
- Carnitine Synthesis
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| Not Available |
| SNPs
| ALDH9A1 |
| Gene Sequence
|
>1485 bp
ATGAGCACTGGCACCTTCGTCGTGTCGCAGCCGCTCAATTACCGTGGCGGGGCCCGCGTG
GAACCAGTGGATGCCTCCGGCACCGAGAAGGCTTTCGAGCCAGCATCCGGTAGGGTGATA
GCTACTTTCACATGTTCAGGAGAAAAGGAAGTAAATTTGGCTGTTCAGGATGCAAAGGCT
GCCTTTAAAATATGGAGTCAAAAATCTGGCATGGAGCGTTGCCGAATCCTTTTGGAGGCT
GCCAGGATAATAAGGGAACGGAGGGATGAAATTGCCACTATGGAGACTATCAACAATGGG
AAGTCCATCTTTGAGGCCCGCTGGGACATTGACACTTCCTGGCAGTGCCTGGAGTACTAT
GCAGGCTTGGCAGGATCCATGGCTGGCGAACACATCCAGCTCCCGGGTGGATCCTTTGGT
TACACCAGAAGGGAACCACTAGGGGTGTGTGTTGGAATAGGAGCGTGGAACTACCCCTTT
CAGATCGCCTGCTGGAAGTCGGCTCCAGCTCTGGCTTGTGGTAACGCCATGGTCTTTAAA
CCTTCTCCCTTCACGCCCGTGTCCGTGTTGCTGCTGGCTGAAATCTATACTGAGGCTGGA
GTCCCTCCTGGGCTCTTCAACGTGGTGCAGGGAGGGGCTGCCACAGGCCAGTTCCTGTGT
CAGCATCGTGATGTGGCCAAAGTCTCCTTCACTGGAAGCGTGCCCACCGGCTCAAAGATC
ATGGAGATGTCTGCTAAAGGAATCAAACCTGTCACCCTGGAACTCGGAGGCAAGTCTCCA
CTTATCATCTTCTCAGACTGTGACATGAAGAATGCTGTGAAGGGGGCGCTGATGGCCAAC
TTCCTTACTCAAGGCGAGGTTTGTTGTAATGGTACAAGGGTATTTGTGCAAAAGGAAATT
CTTGATCAATTTACAGAGGAAGTGGTGAAACAGACGCAAAGGATAAAAATTGGAGATCCC
CTTCTGGAAGATACAAGGATGGGTCCCCTCATCAACCGACCACATCTGGAGCGAGTCCTT
GGGTTTGTTAAAGTGGCAAAGGAGCAGGGTGCTAAAGTGTTATGTGGTGGAGACGTCTTT
GTACCTGAAGACCCCAAATTAAAGGATGGGTATTACATGAGACCTTGTGTGTTAACTAAT
TGCCGAGATGACATGACCTGTGTAAAAGAAGAAATCTTTGGACCAGTTATGTCCATTTTA
TCATTTGACACTGAAGCTGAGGTTCTGGAAAGAGCCAACGACACCACTTTTGGACTAGCT
GCTGGTGTCTTCACCAGGGACATCCAGCGCGCCCACAGAGTGGTGGCGGAGCTCCAGGCT
GGAATGTGCTTCATTAACAACTACAATGTCAGTCCAGTGGAGTTGCCCTTTGGTGGATAT
AAGAAGTCAGGATTCGGCAGAGAGAACGGCCGGGTGACAATTGAGTACTATTCACAGCTG
AAGACCGTGTGTGTGGAGATGGGTGACGTGGAGTCTGCTTTTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 494 |
| Molecular Weight
| 53977.0 |
| Theoretical pI
| 5.88 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>4-trimethylaminobutyraldehyde dehydrogenase
MSTGTFVVSQPLNYRGGARVEPVDASGTEKAFEPASGRVIATFTCSGEKEVNLAVQDAKA
AFKIWSQKSGMERCRILLEAARIIRERRDEIATMETINNGKSIFEARWDIDTSWQCLEYY
AGLAGSMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIACWKSAPALACGNAMVFK
PSPFTPVSVLLLAEIYTEAGVPPGLFNVVQGGAATGQFLCQHRDVAKVSFTGSVPTGSKI
MEMSAKGIKPVTLELGGKSPLIIFSDCDMKNAVKGALMANFLTQGEVCCNGTRVFVQKEI
LDQFTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDVF
VPEDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLA
AGVFTRDIQRAHRVVAELQAGMCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQL
KTVCVEMGDVESAF
|
| External Links |
|---|
| GenBank ID Protein
| AAI05336.1 |
| UniProtKB/Swiss-Prot ID
| Q2KJH9 |
| UniProtKB/Swiss-Prot Entry Name
| AL9A1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC105335 |
| GeneCard ID
| ALDH9A1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
