| Identification |
|---|
| BMDB Protein ID
| BMDBP00609 |
| Secondary Accession Numbers
| None |
| Name
| Transketolase |
| Synonyms
|
Not Available
|
| Gene Name
| TKT |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. |
| Pathways
|
- Pentose Phosphate Pathway
- Warburg Effect
|
| Reactions
|
| D-Erythrose 4-phosphate + Xylulose 5-phosphate → Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 22 |
| Locus
| Not Available |
| SNPs
| TKT |
| Gene Sequence
|
>1872 bp
ATGGAGGCCTACCATAAGCCTGATCAGCAGAAGCTGCAGGCCCTGAAGGACACGGCCAAC
CGCCTGCGTATCAGCTCCATCCAAGCCACCACGGCGGCCGGATCGGGCCACCCCACGTCA
TGCTGCAGCGCTGCTGAGATCATGGCTGTCCTCTTCTTCCACACCATGCGCTACAAGGCC
CTGGATCCCCGGAACCCTCACAACGACCGCTTTGTTCTCTCCAAGGGCCATGCGGCACCC
ATCCTGTATGCCGTCTGGGCTGAAGCTGGCTTCCTGCCGGAGTCAGAGCTGCTGAATCTG
AGGAAGATCAACTCCGACTTGGACGGGCACCCTGTCCCGAAACAAGCCTTCACCGATGTG
GCCACTGGCTCCCTGGGCCAGGGCCTTGGAGCCGCTTGCGGGATGGCCTACACAGGCAAA
TACTTCGACAAAGCCAGCTACCGGGTCTATTGCATGCTGGGAGACGGGGAGCTGTCAGAG
GGCTCCGTGTGGGAGGCCATGGCCTTCGCCAGCATCTACAAGCTGGACAACCTTGTCGCC
ATCCTTGACATCAACCGCCTGGGCCAGAGTGACCCTGCCCCGCTGCAGCACCAGATGGAC
ATCTACCAGAAGCGCTGCGAGGCCTTCGGTTGGAACGCTGTCATCGTAGATGGGCACAGC
GTGGAGGAACTGTGCAAGGCCTTCGGGCAGGTGAAGAACCAGCCAACAGCCATCATTGCC
AAGACCTTCAAGGGCCGAGGCATCACAGGGATAGAAGATAAGGAGTCTTGGCATGGGAAG
CCCCTCCCCAAAAATATGGCCGATCAGATCATCCAGGAAATCTCCGGTCAGATCCAGAGC
AAGAAGAAGATCCTGGCGACCCCCCCAGAGGAGGACGCCCCCTCAGTGGACATCACCAAC
ATCCGAATGCCCACCCCACCCAACTACAAAGTTGGGGACAAGATAGCTACCCGCAAGGCC
TACGGACAGGCCCTGGCCAAGCTGGGTCATGCCAGCAACCGCATCATTGCCCTGGATGGG
GACACCAAGAACTCCACCTTCTCAGAACTCTTCAAAAAGGAGCACCCGGACCGTTTCATT
GAGTGTTACATTGCTGAGCAGAACATGGTGAGCATCGCCGTGGGCTGTGCCACACGCGAC
AGGACGGTACCCTTCTGCAGCACCTTCGCAGCCTTCTTTACACGGGCCTTCGACCAGATT
CGCATGGCAGCCATCTCCGAGAGCAACATCAACCTCTGCGGCTCCCACTGCGGCGTGTCC
ATTGGAGAAGACGGGCCCTCCCAGATGGCCCTGGAAGATCTGGCCATGTTTCGGTCTATC
CCCATGTCAACTGTCTTTTACCCAAGTGATGGGGTGGCTACGGAGAAGGCAGTAGAATTA
GCAGCCAATACAAAGGGTATCTGCTTCATCCGGACCAGCCGCCCAGAAAATGCCATCATC
TACAAACAACATGAAGATTTCCAAATCGGACAAGCCAAGGTGGTCCTGAAGAACAAGGAT
GACCAGGTGACTGTGATTGGTGCCGGGGTGACCCTGCACGAGGCTTTGGCAGCTGCTGAC
CTGCTGAAGAGAGAGAAGATCAACATTCGCGTATTGGACCCTTTCACCATCAAGCCCCTG
GATAAGAAGCTCATTCTTGACAGTGCCCGTGCTACCAAGGGCAGGATCCTCACTGTGGAG
GACCACTACTATGAAGGTGGCATAGGTGAGGCAGTGGCCTCTGCAGTTGTGGGAGAGCCT
GGCGTCACTGTCACCCGCCTGGCAGTCAGCCAGGTGCCCAGAAGCGGGAAACCAGCGGAG
CTGCTGAAGATGTTTGGCATTGACAGGGATGCCATCGCGCAGGCCGTGCGGGGCCTGGTG
ACCAGGGCCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 623 |
| Molecular Weight
| 67906.0 |
| Theoretical pI
| 7.71 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Transketolase
MEAYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKA
LDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLPESELLNLRKINSDLDGHPVPKQAFTDV
ATGSLGQGLGAACGMAYTGKYFDKASYRVYCMLGDGELSEGSVWEAMAFASIYKLDNLVA
ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWNAVIVDGHSVEELCKAFGQVKNQPTAIIA
KTFKGRGITGIEDKESWHGKPLPKNMADQIIQEISGQIQSKKKILATPPEEDAPSVDITN
IRMPTPPNYKVGDKIATRKAYGQALAKLGHASNRIIALDGDTKNSTFSELFKKEHPDRFI
ECYIAEQNMVSIAVGCATRDRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVS
IGEDGPSQMALEDLAMFRSIPMSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII
YKQHEDFQIGQAKVVLKNKDDQVTVIGAGVTLHEALAAADLLKREKINIRVLDPFTIKPL
DKKLILDSARATKGRILTVEDHYYEGGIGEAVASAVVGEPGVTVTRLAVSQVPRSGKPAE
LLKMFGIDRDAIAQAVRGLVTRA
|
| External Links |
|---|
| GenBank ID Protein
| AAT84375.1 |
| UniProtKB/Swiss-Prot ID
| Q6B855 |
| UniProtKB/Swiss-Prot Entry Name
| TKT_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AY675082 |
| GeneCard ID
| TKT |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
