| Identification |
|---|
| BMDB Protein ID
| BMDBP00611 |
| Secondary Accession Numbers
| None |
| Name
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 |
| Synonyms
|
Not Available
|
| Gene Name
| DDAH2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Amino acid transport and metabolism |
| Specific Function
| Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 23 |
| Locus
| Not Available |
| SNPs
| DDAH2 |
| Gene Sequence
|
>858 bp
ATGGGGACGCCAGGGGAGGGGCTGGGCCGCTGCTCCCATGCCCTGATCCGGGGGGTCCCG
GAGAGCCTGGCGTCGGGGGAGGGTGCAGCAGCTGGCCTCCCAGCTCTGGACCTAGCCAAA
GCTCAGAGGGAACATGGGGTGCTGGGGGGTAAGCTGAGGCAGCGATTGGGGCTGCAACTA
GTAGAACTGCCTCCTGAAGAGTCGCTGCCGCTGGGACCGCTGCTCGGTGACACCGCCGTG
ATCCAAGGGGATACGGCTCTAATCACGCGGCCCTGGAGCCCCGCCCGCAGGCCGGAGGTC
GATGGAGTCCGCAAAGCCCTCCAGGACCTGGGGCTCCGAATTGTGGAGATGGGGGACGAG
AACGCAACGCTGGATGGCACTGATGTTCTCTTCACCGGCCGGGAGTTTTTCGTAGGCCTC
TCCAAGTGGACCAATCACCGAGGAGCTGAGATCGTGGCGGACACGTTCCGGGACTTTGCC
GTCTCCACGGTGCCCGTCACAAGCACCTCCCACCTGCGTGGCCTCTGCGGTATGGGGGGA
CCCCGCACCGTGGTGGCGGGTTCCAGCGAAGCTGCCCAAAAAGCTGTCAGGGCAATGGCA
GTGTTGACTGATCACCCCTATGCCTCCCTGACCCTCCCGGATGACGCAGCAGCTGACTGT
CTCTTTCTGCGTCCTGGGCAGCCCGGCCTGCCCCCTTTCCTCCTGCACCGGGGAGGCGGG
GACCTGCCCAACAGCCAAGAGGCACTGCAGAAGCTCTCTGACGTCACCCTCGTACCTGTG
TCCTGTTCAGAACTGGAGAAGGCCGGCGCTGGGCTCAGTTCCCTCTGCCTGGTGCTCAGC
ACACGCCCCCACAACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 285 |
| Molecular Weight
| 29780.0 |
| Theoretical pI
| 5.9 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>N(G),N(G)-dimethylarginine dimethylaminohydrolase 2
MGTPGEGLGRCSHALIRGVPESLASGEGAAAGLPALDLAKAQREHGVLGGKLRQRLGLQL
VELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEMGDE
NATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVTSTSHLRGLCGMGG
PRTVVAGSSEAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGQPGLPPFLLHRGGG
DLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHN
|
| External Links |
|---|
| GenBank ID Protein
| AAI04510.1 |
| UniProtKB/Swiss-Prot ID
| Q3SX44 |
| UniProtKB/Swiss-Prot Entry Name
| DDAH2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC104509 |
| GeneCard ID
| DDAH2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
