| Identification |
|---|
| BMDB Protein ID
| BMDBP00612 |
| Secondary Accession Numbers
| None |
| Name
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| DDAH1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Amino acid transport and metabolism |
| Specific Function
| Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| Not Available |
| SNPs
| DDAH1 |
| Gene Sequence
|
>858 bp
ATGGCTTCTCTCGGCCACCCAGCCACCTTTGGCCGGGCCACCCATGTCGTGGTACGGGCG
CTGCCCGAGTCCCTCGCCCAACAGGCGCTGAGGCGCACCAAGGGCGACGAGGTGGATTTC
GCCCGCGCTGAGCGGCAGCACCAGCTCTACGTGGGCGTGCTGGGCAGTAAACTGGGGCTG
CAGGTGGTGCAGCTGCCCGCCGACGAGAGCCTCCCAGACTGCGTGTTCGTGGAGGACGTG
GCCGTGGTGTGCGAGGAGACGGCCCTGATCACCCGCCCCGGGGCGCCGAGCCGGAGGAAG
GAGGCTGACATGATGAAAGAAGCACTAGAAAAACTTCAGCTCAACATAGTAGAGATGAAA
GATGAAAATGCAACTTTAGATGGTGGAGATGTCTTATTCACAGGCAGAGAATTTTTTGTG
GGCCTTTCCAAAAGGACAAATCAACGAGGTGCGGAAATCTTGGCTGATACTTTTAAGGAC
TATGCGGTCTCCACGGTCCCTGTGGTGGATGCTTTGCACTTGAAGAGTTTCTGCAGCATG
GCTGGGCCTAACCTAATCGCTATTGGATCCAGTGAATCTGCACAGAAGGCCCTCAAGATC
ATGCAACAGATGAGTGATCATCGCTACGACAAACTCACAGTGCCTGATGACACGGCCGCA
AACTGCATATACCTGAATATCCCCAGCAAAGGCCACGTCTTGCTGCACCGAACCCCAGAA
GAGTACCCAGAGAGTGCAAAGGTTTATGAAAAGCTGAAGGACCATATGCTGATCCCCGTG
AGCAATTCTGAACTGGAAAAGGTGGACGGGCTGCTCACCTGCAGCTCGGTTTTAATTAAC
AAGAAAGTAGACTCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 285 |
| Molecular Weight
| 31289.0 |
| Theoretical pI
| 5.88 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
MASLGHPATFGRATHVVVRALPESLAQQALRRTKGDEVDFARAERQHQLYVGVLGSKLGL
QVVQLPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEADMMKEALEKLQLNIVEMK
DENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVVDALHLKSFCSM
AGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDTAANCIYLNIPSKGHVLLHRTPE
EYPESAKVYEKLKDHMLIPVSNSELEKVDGLLTCSSVLINKKVDS
|
| External Links |
|---|
| GenBank ID Protein
| AAI49999.1 |
| UniProtKB/Swiss-Prot ID
| P56965 |
| UniProtKB/Swiss-Prot Entry Name
| DDAH1_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC149998 |
| GeneCard ID
| DDAH1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
