1.0 2018-05-07 22:23:17 UTC 2020-05-20 21:03:20 UTC BMDBP00631 Enzyme AASS Amino acid transport and metabolism Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-oxoglutarate reductase and saccharopine dehydrogenase activity, respectively (By similarity). Amino-acid degradation Glutaryl-CoA from L-lysine: step 1/6. Glutaryl-CoA from L-lysine: step 2/6 L-lysine degradation via saccharopine pathway Lysine Degradation SMP0087203 BMDB0000148 L-Glutamic acid BMDB0000182 L-Lysine BMDB0000208 Oxoglutaric acid BMDB0000217 NADP BMDB0000221 NADPH BMDB0000279 Saccharopine BMDB0000902 NAD BMDB0001263 Allysine BMDB0001487 NADH BMDB0002111 Water 4 >2781 bp ATGCTGCGAGTGTCCAGAACCAAACTGGGCAGGCTGAGCCCCAGCCTCTCCAGAGGGCTT CACCACAAGGCGGTGATGGCCTTGAGGCGGGAGGATGTGAATGCCTGGGAAAGGCGGGCT CCTCTGGCTCCCCGGCACGTCAAAGGGATCACCAACCTGGGATACAAGGTCTTAATACAG CCTTCCAATCGGCGAGCCATTCACGATAAGGAATATGTCAAAGCTGGTGGCATTCTCCAA GAGGATATTTCTGAAGCTTGTCTAATTTTGGGAGTTAAAAGACCGCCAGAGGAAAAATTA ATGCCCAAGAAGACTTATGCATTCTTCTCCCACACAATAAAGGCTCAGGAGGCCAATATG GGTTTGCTGGATGAGATCCTAAAACAGGAAATCCGACTTATTGATTATGAGAAAATGGTG GATCATAGAGGAATACGGGTGGTGGCATTCGGACAGTGGGCAGGTGTGGCAGGAATAATC AACATTCTTCATGGGATGGGTTTAAGGCTCCTTGCTTTGGGACATCACACACCTTTTATG CACATTGGCATGGCTCATAACTACAGGAACAGTGGTCAGGCTGTGCAAGCTGTCCGCGAT GCTGGCTATGAAATATCTTTGGGTTTGATGCCGAAGTCAATAGGGCCCTTAACATTTGTG TTCACAGGGACTGGTAATGTATCTAAGGGAGCCCAAGAAATCTTCAATGAATTACCTTGT GAGTATGTGGAGCCACATGAATTAAAAGAAGTTTCCCAAAATGGAGACCTGAGAAAAGTG TACGGGACAGTGTTAAGTCGCCATCATCATCTTGTCAGGAAAACAGATGGTGTATATGAC CCTGTAGAGTATGACAAATACCCCGAGCGCTACATTAGCCGTTTTAATACTGATATTGCA CCCTATACAACTTGTTTAATTAACGGGATCTACTGGGAACAGAACACCCCTCGTCTACTC ACCCGCCAAGATGCTCAGAGTCTCCTGGCTCCAGGCAAGTCCCCAGTTGCTGGTGTTGAA GGCTGCCCTGCATTGCCACACAAACTTGTGGCAATATGTGACATTTCAGCGGACACAGGA GGATCCATTGAGTTTATGACTGAGTGTACGACCATAGAGCGTCCCTTTTGCATGTATGAT GCAGATCAGCATATTATTCATGACAGTGTGGAAGGCTCTGGGATTCTGATGTGTTCCATT GACAATTTGCCAGCACAGCTTCCAATTGAATCTACAGAATACTTTGGAGACATGCTTTAC CCTTATGTTGAAGAAATGATACTATCAGATGCGACACAGCCTCTTGAAAGTCAGAATTTT TCTCCTGTGGTGCGAGATGCAGTGATTGCATCTAATGGCATGCTGTCTAACAAGTATAAA TATATCCAGAAACTCCGAGAGAACAGGGAACATGCTCAGTCACTTTCAATGGGCACCAAG AAAAAGGTCTTGGTTCTTGGATCTGGTTACGTTTCTGAGCCTGTATTGGAATACCTGTTG AGAGATGACAGTATTGAAATAACAGTAGGTTCTGACATGAAGAATCAAATTGAACAATTA GGCAAGAAATATAATATTAATCCTGTTAGCCTGCACGTTGGTAAACAAGAAGAGAAGTTG AGCTCCTTGGTGGCAACACAGGATCTTGTCATCAGCTTATTGCCTTATGTATTGCATCCT CTTGTGGCCAAGGCATGCATCGCAAGCAAAGTTAACATGATCACTGCAAGCTACATCACC CCAGCGCTAAAAGAATTAGAAAAGAGTGTGGAAGATGCTGGCATCACAGTCATTGGTGAA TTGGGATTGGACCCTGGTCTTGATCATATGTTGGCAATGGAAACAATAGATAAGGCCAAA GAAGTGGGAGCCACGATTGAATCTTATGTTTCCTACTGCGGTGGCCTTCCAGCTCCTGAA TGTTCAGACAATCCTTTGAGATACAAATTTAGCTGGAGTCCAGTGGGAGTTCTGATGAAC ATAATGCAGCCCGCTACCTACCTGCTCAACGGAAAGGTTGTGAATGCTGTAGGAGGTGTC TCCTTTCTGGATTCAGTCACTCCCATGGATTATTTCCCTGGATTAAATTTGGAAGGTTAT CCTAACAGAGACAGTACGAAGTATGCTGAGATTTATGGCATTCCATCTGCTCACACTTTA TTACGAGGGACACTGAGGTACAAGGGGTATGCCAAAGCTTTGAGTGGATTTGTGAAGTTG GGTCTCATAAACAGAGATGCGTTTCCTGCCCTTCAACCTGATGCCAATCCGCTCACCTGG AAAGAACTCCTCTGTGATCTAGTTGGGATTTCATCCTCTTCCAAATGTGATGTGCTTAAG GAAGCTGTCTTTAAGAAACTGGGAGGAGACACAACCCAGTTGGAGGCTCTCGAATGGTTA GGGCTACTCGGGGATGAACAAGTCCCTCAGGCCGAGTCTCTCGTGGATGCCCTCTCCAAG CATCTGGCCGTGAAACTTTCCTATGGTCCTGGAGAGAAAGATATGATTGTGATGAGAGAC AGCTTTGGAATCAGACATCCTTCTGGACATTTGGAAAATAAAACTATTGATCTTGTGGTT TATGGGGATGTCAATGGTTTTTCAGCCATGGCTAAAACTGTGGGGTTACCCACTGCTATG GCAGCCAAGATGTTACTTGATGGTGAAATTCAAGCTAAAGGCCTGATGGGACCCTTTTCA AAGGAGATCTATGGACCAATATTGGAGCGAATTAAAGCAGAAGGCATTATGTATACTACA CAGAGCACAATCAAACTATAA 926 102084.0 6.7 None >Alpha-aminoadipic semialdehyde synthase, mitochondrial MLRVSRTKLGRLSPSLSRGLHHKAVMALRREDVNAWERRAPLAPRHVKGITNLGYKVLIQ PSNRRAIHDKEYVKAGGILQEDISEACLILGVKRPPEEKLMPKKTYAFFSHTIKAQEANM GLLDEILKQEIRLIDYEKMVDHRGIRVVAFGQWAGVAGIINILHGMGLRLLALGHHTPFM HIGMAHNYRNSGQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQEIFNELPC EYVEPHELKEVSQNGDLRKVYGTVLSRHHHLVRKTDGVYDPVEYDKYPERYISRFNTDIA PYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKSPVAGVEGCPALPHKLVAICDISADTG GSIEFMTECTTIERPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIESTEYFGDMLY PYVEEMILSDATQPLESQNFSPVVRDAVIASNGMLSNKYKYIQKLRENREHAQSLSMGTK KKVLVLGSGYVSEPVLEYLLRDDSIEITVGSDMKNQIEQLGKKYNINPVSLHVGKQEEKL SSLVATQDLVISLLPYVLHPLVAKACIASKVNMITASYITPALKELEKSVEDAGITVIGE LGLDPGLDHMLAMETIDKAKEVGATIESYVSYCGGLPAPECSDNPLRYKFSWSPVGVLMN IMQPATYLLNGKVVNAVGGVSFLDSVTPMDYFPGLNLEGYPNRDSTKYAEIYGIPSAHTL LRGTLRYKGYAKALSGFVKLGLINRDAFPALQPDANPLTWKELLCDLVGISSSSKCDVLK EAVFKKLGGDTTQLEALEWLGLLGDEQVPQAESLVDALSKHLAVKLSYGPGEKDMIVMRD SFGIRHPSGHLENKTIDLVVYGDVNGFSAMAKTVGLPTAMAAKMLLDGEIQAKGLMGPFS KEIYGPILERIKAEGIMYTTQSTIKL AAI53852.1 A8E657 AASS_BOVIN BC153851 AASS