| Identification |
|---|
| BMDB Protein ID
| BMDBP00696 |
| Secondary Accession Numbers
| None |
| Name
| Triosephosphate isomerase |
| Synonyms
|
Not Available
|
| Gene Name
| TPI1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Carbohydrate transport and metabolism |
| Specific Function
| Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. |
| Pathways
|
- Carbohydrate biosynthesis
- Carbohydrate degradation
- D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1
- Fructose and Mannose Degradation
- Gluconeogenesis
- Gluconeogenesis.
- Glycolysis
|
| Reactions
|
| Dihydroxyacetone phosphate → D-Glyceraldehyde 3-phosphate |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| TPI1 |
| Gene Sequence
|
>750 bp
ATGGCGCCCTCCAGGAAGTTCTTCGTTGGGGGGAACTGGAAGATGAACGGGAGGAAGAAC
AATCTGGGGGAACTCATCAACACTCTGAACGCGGCCAAGGTGCCAGCCGACACCGAGGTG
GTTTGCGCACCCCCCACCGCCTACATTGACTTCGCCCGGCAGAAGCTAGATCCCAAGATT
GCCGTGGCTGCGCAGAACTGTTACAAAGTGGCCAATGGGGCCTTTACGGGGGAGATCAGC
CCTGGCATGATCAAAGATCTTGGAGCCACGTGGGTAGTCCTGGGGCACTCCGAGAGAAGG
CATGTCTTTGGGGAGTCAGATGAGCTGATTGGGCAGAAAGTGGCCCATGCCCTGGCAGAG
GGACTTGGAGTGATTGCCTGCATTGGGGAGAAGTTAGATGAGAGGGAAGCTGGCATCACG
GAGAAGGTCGTTTTCGAGCAAACCAAGGTCATCGCAGATAACGTGAAGGATTGGAGCAAG
GTTGTCTTGGCCTATGAGCCTGTGTGGGCCATTGGTACTGGCAAGACGGCAACACCGCAA
CAGGCCCAGGAAGTACACGAAAAGCTCCGGGGATGGCTTAAGTCCAACGTCTCTGATGCA
GTGGCTCAGAGCGCCCGCATCATTTATGGGGGTTCTGTGACGGGGGCAACCTGCAAGGAG
CTGGCAAGCCAGCCTGATGTGGATGGCTTCCTTGTGGGCGGTGCTTCCCTCAAGCCTGAG
TTCGTTGACATCATCAATGCCAAACAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 249 |
| Molecular Weight
| 26690.0 |
| Theoretical pI
| 6.93 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Triosephosphate isomerase
MAPSRKFFVGGNWKMNGRKNNLGELINTLNAAKVPADTEVVCAPPTAYIDFARQKLDPKI
AVAAQNCYKVANGAFTGEISPGMIKDLGATWVVLGHSERRHVFGESDELIGQKVAHALAE
GLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQ
QAQEVHEKLRGWLKSNVSDAVAQSARIIYGGSVTGATCKELASQPDVDGFLVGGASLKPE
FVDIINAKQ
|
| External Links |
|---|
| GenBank ID Protein
| AAX09081.1 |
| UniProtKB/Swiss-Prot ID
| Q5E956 |
| UniProtKB/Swiss-Prot Entry Name
| TPIS_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BT021064 |
| GeneCard ID
| TPI1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
