| Identification |
|---|
| BMDB Protein ID
| BMDBP00703 |
| Secondary Accession Numbers
| None |
| Name
| N-acetyl-D-glucosamine kinase |
| Synonyms
|
Not Available
|
| Gene Name
| NAGK |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Carbohydrate transport and metabolism |
| Specific Function
| Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Also has ManNAc kinase activity (By similarity). |
| Pathways
|
- Amino Sugar Metabolism
- Amino-sugar metabolism
- Glutamate Metabolism
- N-acetylneuraminate degradation
|
| Reactions
|
| 3 N-Acetyl-D-Glucosamine 6-Phosphate + 3 Adenosine diphosphate ribose →3 Chitin +3 Adenosine triphosphate |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 11 |
| Locus
| Not Available |
| SNPs
| NAGK |
| Gene Sequence
|
>1035 bp
ATGGTTACGCTGTACGGGGGCGTAGAGGGGGGAGGCACACGATCCAAGGTCCTTTTACTC
TCAGAGGATGGGCAGATCCTGGCAGAAGCGGATGGACTCAGCACAAACCACTGGCTGATC
GGGACAGACAAGTGCGTGGAGAGGATCAACGAGATGGTGAACAGGGCCAAACGGAAAGCA
GGGGTGGATCCTTTGGTTCCTCTCCGAGGCTTGGGCCTATCCCTGAGCGGTGGGGATCAG
GAGGACGCGGTGAGGATGCTGATGGAGGAGCTGAGGGACCGATTTCCCTACCTGAGTGAA
AGCTACTTAATCACCACCGATGCCGCCGGCTCCATCGCCACAGCTACGCCGGATGGTGGG
GTCGTGCTCATCTCTGGGACAGGTTCCAACTGCAGGCTCATCAACCCCGACGGCTCTGAG
AGCGGCTGTGGTGGCTGGGGCCACATGATGGGAGATGAGGGCTCAGCCTACTGGATTGCA
CATCAAGCAGTGAAAATAGTGTTTGACTCCATCGACAACCTCGAGGCGGCTCCTCATGAC
ATTGGCTATGTCAAACAGGCCATGTTCAACTATTTCCAGGTGCCAGATCGGCTAGGAATC
CTCACCCACCTGTATAGGGACTTTGATAAATCCAGGTTTGCTGGGTTTTGCCGGAAAGTT
GCAGAAGGCGCTCAGCAGGGAGACCCCCTTTCCCGTTGCATCTTCAGGAAGGCCGGGGAG
ATGCTAGGCAGACATGTGGTGGCAGTGTTGCCTGAGATTGACCCGGTCTTATTCCAGGGA
GAGATGGGCCTTCCCATCCTGTGCGTGGGCTCTGTGTGGAAGAGCTGGGAGCTGCTGAAG
GAAGGTTTCCTTTTGGCGCTGACCCAAGGCAGAGAGATCCAGGCTCAGAACTCCTTCTCA
GGCTTCACCCTGTTGAAGCTTCGACACTCCTCCGCCCTGGGTGCTGCCAGCCTTGGGGCC
AAGCACATCGGGCACCTCCTCCCCATGGACTACAGCACCAGTGCCATTGCCTTCTACTCC
TATACCTTCTCCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 344 |
| Molecular Weight
| 37268.0 |
| Theoretical pI
| 5.83 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>N-acetyl-D-glucosamine kinase
MVTLYGGVEGGGTRSKVLLLSEDGQILAEADGLSTNHWLIGTDKCVERINEMVNRAKRKA
GVDPLVPLRGLGLSLSGGDQEDAVRMLMEELRDRFPYLSESYLITTDAAGSIATATPDGG
VVLISGTGSNCRLINPDGSESGCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHD
IGYVKQAMFNYFQVPDRLGILTHLYRDFDKSRFAGFCRKVAEGAQQGDPLSRCIFRKAGE
MLGRHVVAVLPEIDPVLFQGEMGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNSFS
GFTLLKLRHSSALGAASLGAKHIGHLLPMDYSTSAIAFYSYTFS
|
| External Links |
|---|
| GenBank ID Protein
| AAI02781.1 |
| UniProtKB/Swiss-Prot ID
| Q3SZM9 |
| UniProtKB/Swiss-Prot Entry Name
| NAGK_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC102780 |
| GeneCard ID
| NAGK |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
