<?xml version="1.0" encoding="UTF-8"?>
<protein>
  <version>1.0</version>
  <creation_date>2018-05-07 22:23:43 UTC</creation_date>
  <update_date>2020-05-20 21:56:59 UTC</update_date>
  <accession>BMDBP00727</accession>
  <secondary_accessions>
  </secondary_accessions>
  <protein_type>Enzyme</protein_type>
  <synonyms>
  </synonyms>
  <gene_name>MT-ATP6</gene_name>
  <general_function>Energy production and conversion</general_function>
  <specific_function>Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.</specific_function>
  <pathways>
  </pathways>
  <metabolite_associations>
    <metabolite>
      <accession>BMDB0001362</accession>
      <name>Hydrogen</name>
    </metabolite>
  </metabolite_associations>
  <go_classifications>
  </go_classifications>
  <subcellular_locations>
  </subcellular_locations>
  <gene_properties>
    <chromosome_location/>
    <locus/>
    <gene_sequence>&gt;957 bp
ATGTTCATAATTAACATCTTAATACTAATTATTCCCATCCTATTGGCCGTAGCATTCCTT
ACGTTAGTGGAACGAAAAGTTCTAGGCTATATACAACTCCGAAAAGGTCCAAATGTCGTA
GGTCCATATGGCCTACTTCAACCCATCGCCGATGCAATCAAACTTTTCATTAAAGAACCA
CTACGACCCGCTACATCTTCAGCCTCAATATTTATCCTAGCACCTATCATAGCTTTAGGC
CTAGCCTTAACCATGTGAATTCCCCTACCAATACCCTATCCTCTTATCAACATAAACCTA
GGAGTCCTATTTATACTAGCCATATCAAGCCTAGCCGTATACTCCATTCTCTGATCAGGC
TGAGCTTCCAACTCAAAATACGCACTAATCGGAGCCCTACGAGCAGTAGCACAAACAATC
TCATACGAAGTAACGCTAGCAATTATCCTGTTATCAGTACTCCTAATAAGTGGGTCCTTT
ACCCTCTCCACATTAATTACTACACAAGAACAAATATGGTTAATCCTCCCAGCATGGCCT
CTAGCAATAATATGATTTATCTCAACACTAGCAGAAACAAACCGAGCTCCATTTGATTTA
ACTGAAGGAGAATCAGAGCTAGTCTCGGGCTTCAACGTAGAATATGCAGCAGGACCATTT
GCCCTCTTCTTCATAGCAGAGTACGCAAATATTATCATAATAAATATCTTTACAGCAATT
TTATTCCTAGGAACATCCCACAATCCACACATACCAGAACTCTACACAATCAATTTTACC
ATTAAATCCCTACTGCTCACAATATCCTTCCTATGAATCCGAGCATCCTACCCTCGATTT
CGCTATGACCAACTAATACACTTACTATGAAAAAATTTTCTACCTCTGACACTAGCCCTG
TGCATGTGACACGTATCCCTACCCATCCTTACATCAGGCATCCCACCACAAACATAA</gene_sequence>
  </gene_properties>
  <protein_properties>
    <residue_number>226</residue_number>
    <molecular_weight>24788.0</molecular_weight>
    <theoretical_pi>10.57</theoretical_pi>
    <pfams>
    </pfams>
    <transmembrane_regions>
      <region>9-29</region>
      <region>68-88</region>
      <region>97-117</region>
      <region>138-158</region>
      <region>164-184</region>
      <region>189-209</region>
    </transmembrane_regions>
    <signal_regions>
      <region>None</region>
    </signal_regions>
    <polypeptide_sequence>&gt;ATP synthase subunit a
MNENLFTSFITPVILGLPLVTLIVLFPSLLFPTSNRLVSNRFVTLQQWMLQLVSKQMMSI
HNSKGQTWTLMLMSLILFIGSTNLLGLLPHSFTPTTQLSMNLGMAIPLWAGAVITGFRNK
TKASLAHFLPQGTPTPLIPMLVIIETISLFIQPMALAVRLTANITAGHLLIHLIGGATLA
LMSISTTTALITFTILILLTILEFAVAMIQAYVFTLLVSLYLHDNT</polypeptide_sequence>
  </protein_properties>
  <genbank_protein_id>CAA24002.1</genbank_protein_id>
  <uniprot_id>P00847</uniprot_id>
  <uniprot_name>ATP6_BOVIN</uniprot_name>
  <pdb_ids>
    <pdb_id>5ARA</pdb_id>
    <pdb_id>5ARE</pdb_id>
    <pdb_id>5ARH</pdb_id>
    <pdb_id>5ARI</pdb_id>
    <pdb_id>5FIJ</pdb_id>
    <pdb_id>5FIK</pdb_id>
    <pdb_id>5FIL</pdb_id>
  </pdb_ids>
  <genbank_gene_id>V00654</genbank_gene_id>
  <genecard_id>MT-ATP6</genecard_id>
  <geneatlas_id/>
  <general_references>
  </general_references>
  <metabolite_references>
  </metabolite_references>
</protein>
