| Identification |
|---|
| BMDB Protein ID
| BMDBP00752 |
| Secondary Accession Numbers
| None |
| Name
| V-type proton ATPase 116 kDa subunit a isoform 1 |
| Synonyms
|
Not Available
|
| Gene Name
| ATP6V0A1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 19 |
| Locus
| Not Available |
| SNPs
| ATP6V0A1 |
| Gene Sequence
|
>2517 bp
ATGGGGGAGCTTTTCCGGAGTGAAGAGATGACACTGGCCCAGCTTTTTCTACAGTCAGAA
GCTGCTTATTGTTGTGTCAGTGAATTAGGTGAACTTGGAAAGGTTCAGTTTCGTGATTTA
AATCCAGATGTGAACGTTTTCCAGAGGAAATTTGTGAATGAAGTTAGAAGATGTGAAGAA
ATGGACCGAAAGCTTCGATTTGTTGAGAAAGAGATAAGGAAAGCTAACATCCCAATTATG
GACACTGGTGAAAACCCAGAGGTGCCCTTCCCCCGGGACATGATTGACTTAGAGGCTAAT
TTTGAGAAGATTGAAAATGAACTGAAGGAAATCAACACAAACCAGGAAGCTCTGAAGAGA
AATTTCCTAGAACTAACTGAATTAAAATTTATACTTCGCAAAACTCAACAGTTTTTTGAT
GAGATGGCGGATCCAGACCTGTTGGAAGAGTCCTCGTCCCTCTTGGAGCCAAGCGAGATG
GGAAGAGGCACGCCCTTGAGACTTGGCTTCGTGGCTGGTGTGATTAACCGGGAGCGCATC
CCTACTTTTGAGCGCATGCTTTGGCGGGTGTGCCGGGGGAATGTGTTCCTGCGGCAGGCT
GAAATCGAGAACCCCCTGGAGGATCCTGTGACTGGAGACTACGTGCACAAGTCTGTGTTC
ATCATTTTCTTCCAAGGCGATCAGCTGAAAAACAGAGTCAAGAAAATCTGTGAAGGGTTC
CGGGCTTCACTCTATCCCTGTCCTGAGACGCCGCAGGAGAGAAAGGAGATGGCTTCTGGA
GTTAATACCAGGATTGATGATCTCCAAATGGTTCTGAACCAAACAGAGGATCACCGCCAG
AGGGTTCTTCAGGCTGCTGCCAAGAACATCCGTGTCTGGTTCATCAAGGTGCGGAAGATG
AAGGCCATCTACCATACTTTGAACCTGTGCAACATAGATGTGACCCAGAAGTGCCTAATT
GCGGAGGTCTGGTGCCCTGTCACTGACCTTGACTCCATCCAGTTTGCGCTCAGAAGGGGC
ACGGAGCACAGTGGTTCCACCGTGCCCTCCATTCTGAACAGGATGCAGACAAACCAGACT
CCCCCCACCTATAACAAGACCAACAAGTTCACGTATGGCTTTCAGAACATAGTGGATGCT
TATGGAATTGGAACTTACCGAGAGATAAATCCAGCTCCATACACCATCATCACTTTCCCT
TTCCTGTTTGCTGTGATGTTTGGTGACCTTGGCCATGGCATTTTGATGACTCTTTTTGCT
GTATGGATGGTGTTAAAAGAGAGCCGGATCCTCTCCCAGAAGAATGAGAATGAGATGTTC
AGCACTATATTCAGCGGCAGGTACATCATTCTGTTGATGGGCGTGTTCTCCATCTACACT
GGCCTCATCTATAACGACTGCTTTTCCAAGTCTCTTAATATCTTTGGGTCATCCTGGAGC
GTACGGCCGATGTTCGATATATACAACTGGACGGAAGAGACACTTCGGGGGAACCCTGTC
CTCCAGCTGAACCCAGCCGTCACTGGAGTTTTTGGTGGACCATATCCTTTTGGCATCGAT
CCAATTTGGAACATTGCTACCAATAAACTGACCTTCCTCAACTCCTTTAAGATGAAGATG
TCTGTTATCCTTGGTATCATCCACATGTTGTTTGGAGTCAGCCTGAGCCTTTTCAACCAC
ACCTACTTCAAGAAGCCCCTGAATATCTACTTTGGATTTATTCCAGAAATAATCTTCATG
ACCTCTTTGTTTGGTTACTTGGTTATCCTTATTTTTTACAAGTGGACGGCCTATAATGCT
AAGACATCGGAGAAAGCACCAAGCCTTCTGATCCATTTCATAAATATGTTCCTCTTTTCC
TATGGGGACTCTGGTAATTCAATGCTGTATTCTGGACAGAAAGGAATTCAGTGTTTCCTG
GTAGTGGTTGCACTGCTGTGTGTCCCTTGGATGCTACTGTTTAAACCACTGGTCCTTCGC
CGTCAGTATTTGAGGAGGAAGCATTTGGGAACTCTCAACTTTGGTGGGATCAGGGTGGGC
AACGGACCGACAGAGGAGGATGCTGAGATTATTCAGCATGACCAGCTCTCCACCCATTCA
GAGGACGCAGAGGAGCCTACCGAGGATGAAGTGTTTGATTTTGGGGACACCATGGTGCAC
CAGGCCATCCACACCATCGAGTACTGCCTGGGCTGCATCTCCAACACCGCCTCCTACCTG
CGGCTCTGGGCCCTCAGCCTCGCTCATGCACAGTTGTCCGAGGTGCTTTGGACCATGGTG
ATCCACATCGGCCTGAAGGTGAAGAGCCTGGCCGGGGGCTTGGCGCTGTTCTTCATCTTT
GCCGCCTTCGCCACCCTGACTGTGGCCATCCTCCTGATCATGGAGGGCCTCTCAGCCTTT
CTCCATGCGCTGCGGTTACACTGGGTGGAGTTCCAGAACAAGTTCTACAGCGGGACTGGC
TTCAAGTTCCTGCCTTTCTCCTTTGAGCACATCCGGGAAGGGAAGTTTGATGACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 838 |
| Molecular Weight
| 96302.0 |
| Theoretical pI
| 6.6 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 389-407
- 410-426
- 442-471
- 536-555
- 574-594
- 640-659
- 726-750
- 772-810
|
| Protein Sequence
|
>V-type proton ATPase 116 kDa subunit a isoform 1
MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
NFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPSEMGRGTPLRLGFVAGVINRERI
PTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGF
RASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKM
KAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQT
PPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDLGHGILMTLFA
VWMVLKESRILSQKNENEMFSTIFSGRYIILLMGVFSIYTGLIYNDCFSKSLNIFGSSWS
VRPMFDIYNWTEETLRGNPVLQLNPAVTGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKM
SVILGIIHMLFGVSLSLFNHTYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYNA
KTSEKAPSLLIHFINMFLFSYGDSGNSMLYSGQKGIQCFLVVVALLCVPWMLLFKPLVLR
RQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEEPTEDEVFDFGDTMVH
QAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLKVKSLAGGLALFFIF
AAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFDD
|
| External Links |
|---|
| GenBank ID Protein
| AAA21492.1 |
| UniProtKB/Swiss-Prot ID
| Q29466 |
| UniProtKB/Swiss-Prot Entry Name
| VPP1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| L31770 |
| GeneCard ID
| ATP6V0A1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
