| Identification |
|---|
| BMDB Protein ID
| BMDBP00805 |
| Secondary Accession Numbers
| None |
| Name
| UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase |
| Synonyms
|
Not Available
|
| Gene Name
| DPAGT1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Cell wall/membrane/envelope biogenesis |
| Specific Function
| Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol. |
| Pathways
|
- Protein glycosylation
- Protein modification
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 15 |
| Locus
| Not Available |
| SNPs
| DPAGT1 |
| Gene Sequence
|
>1227 bp
ATGTGGGCCTTCCCGGAGTTGCCTATGCCGCTGTTGGTGAATTTGATCGGCTCGCTGATG
GGATTTGTGGCCACAGTGACCCTTATCCCTGCTTTCCGAGGCCACTTCATCGCCGCGCGC
CTCTGTGGCCAGGACCTCAACAAATCCAGCCGGGAGCAAATCCCAGAGTCCCAGGGAGTG
ATCAGCGGTGCTGTTTTCCTTATCATACTCTTCTGCTTCATCCCTTTCCCTTTCCTGAAC
TGCTTTGTGGAGCAGCAGTGTAAAGCCTTCCCCCACCATGAATTTGTGGCCCTGATAGGT
GCACTCCTTGCCATCTGCTGCATGATTTTCCTGGGCTTCGCGGATGATGTACTGAATTTG
CGCTGGCGCCATAAGCTGCTGCTGCCCACAGCTGCCTCACTACCTCTCCTCATGGTCTAT
TTCACCAACTTTGGCAACACGACCATTGTGGTACCCAAGCCCTTACGCCCGATCCTTGGC
CTGCATCTGGACTTGGGGATCCTGTACTATGTCTACATGGGGCTGCTGGCAGTGTTCTGT
ACCAATGCCATTAATATTCTAGCAGGAATTAATGGCCTTGAGGCTGGCCAGTCACTCGTC
ATTTCTGCTTCCATCATTGTCTTCAACTTGGTGGAGCTGGATGGTGATTATCGAGATGAT
CACATCTTTTCTCTCTACTTCATGATACCCTTTTTTTTCACCACCTTGGGACTGCTCTAC
CATAACTGGTACCCATCACGGGTGTTTGTGGGAGATACCTTCTGTTACTTTGCTGGCATG
ACCTTTGCCGTGGTGGGCATCTTGGGACACTTCAGCAAGACCATGCTCCTCTTCTTCATG
CCCCAGGTGTTCAACTTCCTCTACTCACTGCCTCAGCTCCTGCATATCATCCCCTGTCCT
CGCCACCGTATGCCCAGACTCAATACCAAGACAGGCAAACTGGAGATGAGCTATTCCAAG
TTCAAGACCAAGAGCCTCTCTTTCTTGGGCACCTTTATTCTAAAGGTAGCAGAGAACCTT
GGGCTACTGACGGTGCGCCACAGTGAGGATGAGGATGGTGCCTTCACGGAATGTAACAAC
ATGACCCTCATCAACTTGCTACTTAAAGTCTTTGGGCCCATGCATGAGAGAAACCTCACC
CTCCTCCTGCTGTTGCTACAGGTCGTCGGTAGTGCTGTCACCTTCTCCATTCGGTACCAG
CTTGTCCGACTCTTCTATGATGTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 408 |
| Molecular Weight
| 46045.0 |
| Theoretical pI
| 7.94 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 11-38
- 59-78
- 92-118
- 122-143
- 167-186
- 193-213
- 219-242
- 251-269
- 272-293
- 376-400
|
| Protein Sequence
|
>UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
MWAFPELPMPLLVNLIGSLMGFVATVTLIPAFRGHFIAARLCGQDLNKSSREQIPESQGV
ISGAVFLIILFCFIPFPFLNCFVEQQCKAFPHHEFVALIGALLAICCMIFLGFADDVLNL
RWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPLRPILGLHLDLGILYYVYMGLLAVFC
TNAINILAGINGLEAGQSLVISASIIVFNLVELDGDYRDDHIFSLYFMIPFFFTTLGLLY
HNWYPSRVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCP
RHRMPRLNTKTGKLEMSYSKFKTKSLSFLGTFILKVAENLGLLTVRHSEDEDGAFTECNN
MTLINLLLKVFGPMHERNLTLLLLLLQVVGSAVTFSIRYQLVRLFYDV
|
| External Links |
|---|
| GenBank ID Protein
| AAX08721.1 |
| UniProtKB/Swiss-Prot ID
| Q5EA65 |
| UniProtKB/Swiss-Prot Entry Name
| GPT_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT020704 |
| GeneCard ID
| DPAGT1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
