| Identification |
|---|
| BMDB Protein ID
| BMDBP00853 |
| Secondary Accession Numbers
| None |
| Name
| Glutamine--tRNA ligase |
| Synonyms
|
Not Available
|
| Gene Name
| QARS1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Translation, ribosomal structure and biogenesis |
| Specific Function
| Glutamine--tRNA ligase. Plays a critical role in brain development. |
| Pathways
|
- Glutamate Metabolism
- Protein Synthesis: Glutamine
|
| Reactions
|
| L-Glutamine + Adenosine triphosphate + tRNA(Gln) → Adenosine monophosphate + Pyrophosphate + L-Glutaminyl-tRNA(Gln) |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 22 |
| Locus
| Not Available |
| SNPs
| QARS1 |
| Gene Sequence
|
>2328 bp
ATGGCGGCTTTGGACTCCTTGTCGCTCTTCACTGGCCTCGGCCTGAGCGAGCAGAAGGCC
CGCGAAACGCTCAAGAACACGGTTCTGAGCGCGCAGCTACGCGAGGCGGCGACCCAGGCG
CAGCAGACTCTGGGCTCCTCCATCGACAAGGCTACCGGGACCCTGCTCTATGGATTGGCC
TCCCGACTCCGGGATCCTCGGCGCCTTTCTTTCCTCGTGAGCTACATAACCAGTAGGAAG
ATCCACACTGAGACCCAGCTGAGCGCTGCCCTTGAGTATGTGCGGAGTCATCCCTTGGAT
CCCATCAACACTGAGGACTTCGAGCAGGAATGCGGTGTGGGCGTTGTGGTGACCCCAGAA
CAGATTGAAGAGGCCGTGGAGGCTGCCATAAATCGCCACCGAGCCAAGCTCCTGGTAGAG
CGTTACCATTTCAGCATGGGGCTGCTGATGGGAGAGGCTCGGGCTGCACTCAAGTGGGCA
GATGGCAAAATGATCAAGCATGAAGTAGACATGCAGGTCCTCCATCTTCTGGGTCCCAAG
ACAGAGACTGATCTGGAGAAGAAGCCCAAGGTGGCAAAGGCTCGGCCAGAAGAGACAGAC
CAAAGGACAGCAAAGGATGTGGTGGAGAATGGTGAGGTTGTTGTTCAGACCCTGTCTCTG
ATGGAGCAGCTCCGAGGCGAGGCACTTAAGTTCCACAAACCTGGTGAGAACTACAAGACC
CCGGGCTATGTGACCACTCCTCATACCATGGATCTACTGAAGCAGCACCTGGACATCACC
GGAGGACAGGTTCGTACCCGGTTCCCGCCAGAACCCAATGGAATCCTGCACATTGGACAT
GCCAAAGCAATCAATTTCAATTTTGGCTATGCCAAGGCCAACAATGGGATCTGTTTCCTG
CGCTTTGATGACACCAACCCTGAGAAAGAGGAAGCAAAGTTCTTCACTGCCATATACGAC
ATGGTGGCCTGGCTGGGTTACACCCCTTACAAGGTGACATATGCCTCCGATTATTTTGAC
CAGCTGTATGCCTGGGCTGTGGAGCTTATCCGCAGGGATCAGGCCTACGTGTGCCACCAG
CGAGGAGAGGAGCTCAAAGGCCACAACCCACTGCCCTCACCCTGGAGAGACCGTCCCATA
GAGGAGTCGCTGCTGCTCTTCGAGGCAATGCGCAAGGGCAAGTTTGCTGAGGGTGAGGCC
ACATTGCGGATGAAGCTGGTGATGGAGGATGGCAAGATGGACCCCGTGGCCTACCGCGTC
AAGTACACGCCGCACCACCGCACAGGGGACACCTGGTGCATCTACCCCACCTATGACTAC
ACGCACTGCCTCTGTGACTCCATCGAGCACATCACCCACTCACTCTGCACCAAGGAATTC
CAGGCCCGACGCTCCTCCTACTTCTGGCTGTGCAATGCGCTGGACGTCTACTGTCCCGTG
CAGTGGGAGTACGGCCGCCTCAATCTGCACTATGCTGTCGTCTCCAAGAGGAAGATTCTC
CAGCTTGTGGCGGCTGGCGCTGTGCGGGATTGGGACGATCCCCGGCTCTTCACGCTCACA
GCCTTACGACGCCGGGGCTTTCCGCCCGAGGCCATCAACAACTTCTGTGCTCGGGTGGGA
GTGACAGTGGCACAGACCACAATGGAACCACATCTGCTAGAAGCCTGTGTGCGTGATGTG
CTGAATGACACAGCCCCTCGGGCCATGGCTGTGCTGGAGCCGTTACAGGTGGTCATCACC
AATTTTCCTGCCACCAAGGCCTTGGACATCCAGGTGCCCAACTTCCCAGCTGATGAGACC
AAGGGCTTCCATCAGGTTCCTTTTGGATCCACTGTTTTCATTGAAAGGATGGACTTCAAA
GAGGAGCCAGAGCCAGGCTATAAGCGCCTGGCATGGGGCCAGCCCGTGGGCCTGAGGCAT
ACAGGCTACGTCATCGAGCTGCAGCATGTTGTCAAGGGCCCCAGTGGCTGTGTGGAAAGC
CTCAAGGTGACCTGCAGGCGCGCAGATGCTGGTGAAAAGCCCAAGGCATTTATTCACTGG
GTATCACAGCCTCTGACATGTGAGATCCGCCTCTATGAGCGACTATTTCAGCACAAGAAC
CCCGAGGATCCTGCTGAGGTGCCTGGTGGATTCTTAAGTGACCTGAACCCGGCCTCGCTA
CAAGTGGTGGAGGCTGCATTAGTGGACTGTTCTGTGGCCCTGGCAAAGCCCTTCGACAAG
TTCCAATTTGAGCGCCTTGGTTACTTTTCCGTGGATCCAGACAGCAACCAGGGACAGCTT
GTCTTCAACCGAACCGTCACACTGAAGGAGGACCCAGGAAAAGTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 775 |
| Molecular Weight
| 87643.0 |
| Theoretical pI
| 6.89 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Glutaminyl-tRNA synthetase
MAALDSLSLFTGLGLSEQKARETLKNTVLSAQLREAATQAQQTLGSSIDKATGTLLYGLA
SRLRDPRRLSFLVSYITSRKIHTETQLSAALEYVRSHPLDPINTEDFEQECGVGVVVTPE
QIEEAVEAAINRHRAKLLVERYHFSMGLLMGEARAALKWADGKMIKHEVDMQVLHLLGPK
TETDLEKKPKVAKARPEETDQRTAKDVVENGEVVVQTLSLMEQLRGEALKFHKPGENYKT
PGYVTTPHTMDLLKQHLDITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL
RFDDTNPEKEEAKFFTAIYDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRDQAYVCHQ
RGEELKGHNPLPSPWRDRPIEESLLLFEAMRKGKFAEGEATLRMKLVMEDGKMDPVAYRV
KYTPHHRTGDTWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV
QWEYGRLNLHYAVVSKRKILQLVAAGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG
VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLEPLQVVITNFPATKALDIQVPNFPADET
KGFHQVPFGSTVFIERMDFKEEPEPGYKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES
LKVTCRRADAGEKPKAFIHWVSQPLTCEIRLYERLFQHKNPEDPAEVPGGFLSDLNPASL
QVVEAALVDCSVALAKPFDKFQFERLGYFSVDPDSNQGQLVFNRTVTLKEDPGKV
|
| External Links |
|---|
| GenBank ID Protein
| ABF57443.1 |
| UniProtKB/Swiss-Prot ID
| Q3MHH4 |
| UniProtKB/Swiss-Prot Entry Name
| SYQ_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT025487 |
| GeneCard ID
| QARS1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
