| Identification |
|---|
| BMDB Protein ID
| BMDBP00865 |
| Secondary Accession Numbers
| None |
| Name
| Geranylgeranyl pyrophosphate synthase |
| Synonyms
|
Not Available
|
| Gene Name
| GGPS1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Coenzyme transport and metabolism |
| Specific Function
| Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. |
| Pathways
|
- Farnesyl diphosphate biosynthesis
- Farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.
- Geranyl diphosphate biosynthesis
- Geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.
- Geranylgeranyl diphosphate biosynthesis
- Geranylgeranyl diphosphate from farnesyl diphosphate and isopentenyl diphosphate: step 1/1
- Isoprenoid biosynthesis
- PATHWAY: Isoprenoid biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 28 |
| Locus
| Not Available |
| SNPs
| GGPS1 |
| Gene Sequence
|
>903 bp
ATGGAGAAGACTCAAGAAACCGTCCAAAGAATTCTTCTAGAACCTTACAAGTACTTACTT
CAGTTACCAGGTAAACAAGTGAGAACCAAACTTTCACAGGCGTTTAATCATTGGCTAAAA
GTTCCAGAAGACAAGTTACAGATTATCATTGAAGTGACAGAAATGTTGCATAATGCCAGT
TTACTCATCGATGATATTGAAGACAACTCAAAACTCCGACGTGGCTTTCCAGTGGCACAC
AGTATCTATGGAATTCCATCTGTCATCAATTCTGCTAATTATGTATATTTTCTTGGCCTA
GAGAAAGTCTTAACCCTCAATCACCCGGATGCAGTAAAGCTCTTTACCCGCCAGCTTTTA
GAACTCCATCAGGGACAAGGCCTAGATATCTACTGGAGGGATAATTACACTTGTCCCACC
GAAGAAGAATATAAAGCAATGGTGCTGCAAAAGACAGGTGGACTATTTGGATTAGCAGTA
GGTCTCATGCAGTTGTTCTCTGATTACAAAGAAGATTTAAAACCACTACTTGATACACTT
GGGCTCTTTTTCCAAATTAGGGATGATTACGCTAATCTACACTCCAAAGAATACAGTGAA
AACAAAAGCTTTTGTGAAGATCTAACAGAGGGAAAGTTCTCATTCCCTACTATTCATGCT
ATCTGGTCAAGGCCAGAAAGCACCCAGGTGCAGAATATCTTACGCCAGAGAACCGAAAAC
ATAGATATTAAAAAATACTGTGTACATTACCTTGAGAATGTAGGTTCCTTTGAATATACT
CGGAATACTCTTAAAGAGCTTGAATCTAAAGCCTATAAACAAATTGATGCTCGTGGTGGA
AACCCTGAGCTAGTAGCTCTAATAAAACACTTAAGTAAAATGTTCAAAGAAGAGAATGAA
TAA
|
| Protein Properties |
|---|
| Number of Residues
| 300 |
| Molecular Weight
| 34900.0 |
| Theoretical pI
| 6.25 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Geranylgeranyl pyrophosphate synthetase
MEKTQETVQRILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNAS
LLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLTLNHPDAVKLFTRQLL
ELHQGQGLDIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLDTL
GLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPESTQVQNILRQRTEN
IDIKKYCVHYLENVGSFEYTRNTLKELESKAYKQIDARGGNPELVALIKHLSKMFKEENE
|
| External Links |
|---|
| GenBank ID Protein
| AAI20314.1 |
| UniProtKB/Swiss-Prot ID
| P56966 |
| UniProtKB/Swiss-Prot Entry Name
| GGPPS_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC120313 |
| GeneCard ID
| GGPS1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
