| Identification |
|---|
| BMDB Protein ID
| BMDBP00907 |
| Secondary Accession Numbers
| None |
| Name
| Peroxisomal acyl-coenzyme A oxidase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| ACOX1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. |
| Pathways
|
- Bile Acid Biosynthesis
- Lipid metabolism
- Peroxisomal fatty acid beta-oxidation
|
| Reactions
|
| 3a,7a-Dihydroxy-5b-cholestanoyl-CoA + Water → 3a,7a-Dihydroxy-5b-cholest-24-enoyl-CoA |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 19 |
| Locus
| Not Available |
| SNPs
| ACOX1 |
| Gene Sequence
|
>1983 bp
ATGAATCCAGACCTGCAGAAAGAGCGGGCCGGCGCCAGCTTCAACCCGGAGCTGCTCACG
AATGTCCTGGACGGCAGCCCCGAGAACACTCGGCGCCGCCGAGAGATCGAGAACCTCATT
CTGAACGACCCAGACTTCCAGCATGAGAACTTGAATTTCCTCAGCCGTAGCCAGCGTTAC
GAGGTGGCTGTTAAGAAGAGTGCCATCATGGTGCAGAAGATGAGGAAGTTTGGCATCGCA
GATCCTGCTGAAATCATGTGGTTTAAAAAACTACATTTGGTCAATTTTGTGGAACCTGTG
GGCCTCAATTACTCCATGTTTATTCCTACCTTGCTGAATCAGGGCACCACTGCTCAGCAA
GAGAAATGGCTGCATTCATCCAAAGGACTCGAGATAATTGGCACCTACGCCCAGACGGAA
ATGGGCCACGGAACCCATCTTCGAGGCTTGGAAACCACAGCCACTTATGACCCTGAAACC
CAGGAGTTCATTCTCAACAGTCCTACTGTGACCTCCATCAAGTGGTGGCCTGGTGGACTT
GGAAAAACTTCAAATCATGCTATCGTACTTGCCCAGCTCTTCACTCAGGGAAAATGCTAT
GGATTACATGCCTTCATTGTACCTATTCGTGAACTTGGGACCCATAAGCCTTTGCCAGGT
ATTACTGTAGGAGACATTGGCCCCAAGTTTGGCTATGATGAGATGGATAATGGCTACTTG
AAGATGGACAACTATCGTATTCCCAGAGAAAACATGCTGATGAAACATGCCCAGGTGAAG
CCTGATGGCACATACGTAAAACCCCTGAATAACAAGCTGACCTACGGGACCATGGTGTTC
ATCAGGTCCTTCCTCGTGGGAGAATCCGCTCGGAGTCTGTCTAAGGCATGCACCATTGCC
GTCCGATACAGTGCTGTGAGGCATCAGTCTGAAATCAACCCAGGTGAACCAGAACCACAG
ATTTTGGATTATCAAACCCAGCAATATAAACTTTTCCCCCTCCTGGCCACTGCCTATGCC
TTCCAGTTTGTAGGCGCATACATGAAAGAGACCTATCTTCGGATTAATGAAGACATTGGC
CATGGGGACCTGAGTGAGCTGCCTGAGCTTCACGCGCTCACCGCTGGGCTGAAGGCTTTC
ACGTCCTGGACAACGAACACAGCTATTGAAGCCTGTCGGATGGCTTGTGGCGGACATGGC
TATTCTCACTGCAGTGGACTTCCAAATATTTATGTCACTTTTACCCCAACCTGCACCTTC
GAGGGGGAAAACACTGTCATGATGCTGCAGACAGCCAGGTTCCTGATGAAAAGTTACGAC
CAGGTGCACTCAGGCAAGTTGGTGTGTGGCATGGTGTCCTACTTGAATGACCTGCCCAGC
CAGCGCATCCAGCCACAGCAGGTGGCTGTGTGGCCAACTATGGTGGATATCAACAGCCCC
GACAGCCTGACAGAGGCGTACAAGCTTCGAGCGGCCAGATTAGTAGAAATTGCTGCTAAA
AACCTTCAGACTGAAGTGATTCACAGAAAAAGCAAGGAGGTAGCGTGGAACCTAACGTCC
ATTGACCTTGTTCGGGCAAGTGAGGCACATTGCCACTATGTGGTGGTTAAGCTCTTTACG
GAAAAAGTCCTCCAGATTCAAGAGAAGTCCATCCAAGCTGTCCTAAGGCGTTTGTGTCTC
TTGTATTCTTTGTATGGAATCAGTCAGAATGCAGGGGATTTTCTTCAGGGGAGCATCATG
ACAGAGTCTCAGATCACCCAGGTGAATGGGCGCATCAAGGAGCTGCTGACTGCGATTCGC
CCTGACGCGGTTGCTCTGGTGGATGCATTTGATTTTCAGGATGTGACACTGGGCTCTGTG
CTTGGCCGCTATGATGGCAATGTGTACGAAAACTTGTTTGAATGGGCCAAGAAATCCCCA
CTGAACAAAACAGAGGTCCATGAGTCTTACAAGCACCTAAAGTCGCTGCAGTCCAAGCTC
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 660 |
| Molecular Weight
| 74379.0 |
| Theoretical pI
| 7.83 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Peroxisomal acyl-coenzyme A oxidase 1
MNPDLQKERAGASFNPELLTNVLDGSPENTRRRREIENLILNDPDFQHENLNFLSRSQRY
EVAVKKSAIMVQKMRKFGIADPAEIMWFKKLHLVNFVEPVGLNYSMFIPTLLNQGTTAQQ
EKWLHSSKGLEIIGTYAQTEMGHGTHLRGLETTATYDPETQEFILNSPTVTSIKWWPGGL
GKTSNHAIVLAQLFTQGKCYGLHAFIVPIRELGTHKPLPGITVGDIGPKFGYDEMDNGYL
KMDNYRIPRENMLMKHAQVKPDGTYVKPLNNKLTYGTMVFIRSFLVGESARSLSKACTIA
VRYSAVRHQSEINPGEPEPQILDYQTQQYKLFPLLATAYAFQFVGAYMKETYLRINEDIG
HGDLSELPELHALTAGLKAFTSWTTNTAIEACRMACGGHGYSHCSGLPNIYVTFTPTCTF
EGENTVMMLQTARFLMKSYDQVHSGKLVCGMVSYLNDLPSQRIQPQQVAVWPTMVDINSP
DSLTEAYKLRAARLVEIAAKNLQTEVIHRKSKEVAWNLTSIDLVRASEAHCHYVVVKLFT
EKVLQIQEKSIQAVLRRLCLLYSLYGISQNAGDFLQGSIMTESQITQVNGRIKELLTAIR
PDAVALVDAFDFQDVTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYKHLKSLQSKL
|
| External Links |
|---|
| GenBank ID Protein
| AAI02762.1 |
| UniProtKB/Swiss-Prot ID
| Q3SZP5 |
| UniProtKB/Swiss-Prot Entry Name
| ACOX1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC102761 |
| GeneCard ID
| ACOX1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
