1.0 2018-05-07 22:24:50 UTC 2020-05-20 21:07:28 UTC BMDBP00968 Enzyme UBE2F Involved in ATP binding Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5. Protein modification Protein neddylation BMDB0000182 L-Lysine 3 >558 bp ATGCTGACGCTGGCAAGCAAGCTGAAGCGGGATGATGGTCTCAAAGGGTCCCGGGCGTCA GCCACAGCCTCTGACTCCACTCGGCGGGTGTCTGTGAGGGACAGGCTGCTTGTTAAAGAG GTTGCAGAACTTGAAGCTAATTTACCTTGTACGTGTAAAGTGCATTTTCCTGATCCAAAC AAGCTTCATTGCTTTCAGCTAACTGTCACCCCAGATGAGGGTTACTACCAGGGTGGAAAA TTTCAGTTTGAAACTGAAGTTCCTGACGCATACAACATGGTGCCTCCCAAAGTGAAATGC TTGACCAGGATCTGGCACCCCAACATCACCGAGACTGGTGAGATATGTCTCAGCTTACTG AGAGAACACTCGATCGACGGCACCGGCTGGGCCCCCACAAGGACGCTGAAGGATGTTGTT TGGGGATTAAACTCTTTGTTTACTGATCTGTTGAATTTTGATGATCCACTGAATATTGAA GCTGCGGAACATCATTTGCGAGACAAGGAGGACTTCCGGAATAAAGTGGAGGACTACATT AAGCGCTACGCCAGATGA 185 21133.0 6.78 None >NEDD8-conjugating enzyme UBE2F MLTLASKLKRDDGLKGSRASATASDSTRRVSVRDRLLVKEVAELEANLPCTCKVHFPDPN KLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTRIWHPNITETGEICLSLL REHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVEDYI KRYAR AAI14676.1 Q1RMW1 UBE2F_BOVIN BC114675 UBE2F