| Identification |
|---|
| BMDB Protein ID
| BMDBP00994 |
| Secondary Accession Numbers
| None |
| Name
| Fatty acyl-CoA reductase 2 |
| Synonyms
|
Not Available
|
| Gene Name
| FAR2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Secondary metabolites biosynthesis, transport and catabolism |
| Specific Function
| Catalyzes the reduction of saturated but not unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. A lower activity can be observed with shorter fatty acyl-CoA substrates. It may play a role in the production of ether lipids/plasmalogens and wax monoesters which synthesis requires fatty alcohols as substrates. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| FAR2 |
| Gene Sequence
|
>1548 bp
ATGTCCATGATTGCAGCTTTCTATGGTGGCAAGTCCATTCTCATTACTGGGGCCACGGGC
TTCATGGGCAAAGTGTTGATGGAGAAGCTATTTCGCACCAGCCCAGACCTGAAAGTCGTT
TACATCCTGGTGAGGCCCAAGCAGGGCCAGACCCTGCAGCAGAGGGTTTTCCAGATCCTA
GACAGTAAGCTGTTTGAAAAAGTCAAAGAAGTTTGTCCAAATGTGCATGAGAAGATCCGA
GCTATTTCTGCAGACCTCAATCAGAATGACTTTGCCATCAGCAAGGAGGACATGAAGGAG
CTTCTTTCCCACACAAACATCATCTTCCACTGTGCCGCTACCGTGCGCTTTGATGACCAC
CTCAGACATGCTGTGCAGCTTAATGTCACTGCCACCCAGCAGCTTTTGCTCATGGCCAGT
CAGATGCCGAAGCTGGAAGCCTTCATACACATTTCTACTGCCTTTTCAAATTGTAACCTG
AAGCACATTGACGAAGTCGTCTATCCATGTCCTGTGGAGCCAAAAAAAATCATTGACTCC
ATGGAGTGGTTAGACGACGCTATTATTGACGAGATCACACCGAAACTGATCGGAGATTGG
CCTAACACATACACCTATACCAAGGCCTTGGGAGAGGTGGTGGTGCAGCAGGAAGGTGGC
AACCTCAACATTGCCATCATACGGCCCTCCATCATGGGAGCAACGTGGCAGGAGCCCTTC
CCAGGTTGGGTTGATAACTTAAATGGACCTAGTGGGCTCATTATTGCGGCTGGGAAAGGG
TTTCTTCGGTCCATAAGAGCTACTCCGATGGCTGTGGCAGATTTGATTCCAGCAGACACA
GTGGTCAATCTCACTTTGGCTGTAGGATGGTACACGGCAGTTCACAGACCTAAGTCGACA
TTGGTCTACCACTGTACATCTGGCAACCTCAATCCCTGTAACTGGGGCAAAATGGGACTC
CAAGTCTTGGCAACCTTTGAAAAAATCCCATTTGAGAGAGCTTTCAGGAGGCCGAACGCT
GACTTCACAACCAACAACATCACAACCCATTACTGGAATGCTGTCAGTCACCGGGCCCCT
GCCATCATCTATGACTTCTATCTTCGTCTCACAGGAAGGAAGCCCAGGATGACAAAGCTC
ATGAATCGGCTTTTAAGAACCCTTTCCATGCTGGAGTATTTCGTCAACCGGAGCTGGGAA
TGGAGCACCTACAACACTGAAATGCTGATGTCCGAGCTGAGTCCCGAAGACCAGAGAGTA
TTCAACTTTGATGTACGTCAGCTGAACTGGTTAGAATACATTGAAAATTATGTTTTAGGA
GTTAAGAAGTACTTATTGAAAGAGGATATGGCTGGGATCCCAGAAGCAAAGCAACACTTA
AAAAGGCTCCGAAATATTCACTACCTCTTTAATACTGCTCTCTTCCTCATCGCCTGGCGT
CTTCTCATTGCAAGATCTCAGGTGGCTCGGAATGTGTGGTTCTTCATCGTGAGCTTCTGT
TACAAATTCCTCTCCTACTTTAGGGCATCTAGCACACTTAATGTCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 515 |
| Molecular Weight
| 59077.0 |
| Theoretical pI
| 9.38 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Fatty acyl-CoA reductase 2
MSMIAAFYGGKSILITGATGFMGKVLMEKLFRTSPDLKVVYILVRPKQGQTLQQRVFQIL
DSKLFEKVKEVCPNVHEKIRAISADLNQNDFAISKEDMKELLSHTNIIFHCAATVRFDDH
LRHAVQLNVTATQQLLLMASQMPKLEAFIHISTAFSNCNLKHIDEVVYPCPVEPKKIIDS
MEWLDDAIIDEITPKLIGDWPNTYTYTKALGEVVVQQEGGNLNIAIIRPSIMGATWQEPF
PGWVDNLNGPSGLIIAAGKGFLRSIRATPMAVADLIPADTVVNLTLAVGWYTAVHRPKST
LVYHCTSGNLNPCNWGKMGLQVLATFEKIPFERAFRRPNADFTTNNITTHYWNAVSHRAP
AIIYDFYLRLTGRKPRMTKLMNRLLRTLSMLEYFVNRSWEWSTYNTEMLMSELSPEDQRV
FNFDVRQLNWLEYIENYVLGVKKYLLKEDMAGIPEAKQHLKRLRNIHYLFNTALFLIAWR
LLIARSQVARNVWFFIVSFCYKFLSYFRASSTLNV
|
| External Links |
|---|
| GenBank ID Protein
| AAI19969.1 |
| UniProtKB/Swiss-Prot ID
| Q0P5J1 |
| UniProtKB/Swiss-Prot Entry Name
| FACR2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC119968 |
| GeneCard ID
| FAR2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
