1.0 2018-05-07 22:25:05 UTC 2020-05-20 21:10:29 UTC BMDBP01024 Enzyme PYCR1 Amino acid transport and metabolism Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Involved in the cellular response to oxidative stress. Amino-acid biosynthesis L-proline biosynthesis L-proline from L-glutamate 5-semialdehyde: step 1/1 BMDB0000162 L-Proline BMDB0000217 NADP BMDB0000902 NAD BMDB0001301 1-Pyrroline-5-carboxylic acid 19 >963 bp ATGAGCGTGGGCTTCATCGGGGCTGGCCAGTTGGCCTTTGCGCTGGCCAAGGGCTTCACA GCAGCAGGTGTTGTTGCTGCCCACAAGATAATGGCCAGTTCTCCAGACATGGACCTGGCC ACCGTTTCTGCCCTCAGGAAGATGGGGGTGAACCTCACGCATCACAACAAGGAGACCGTG CAGCACAGCGACGTGCTCTTCCTGGCCGTGAAGCCACACATCATCCCCTTCATCCTGGAT GAGATCGCCGCCAACATTGAGGCTCGGCACATCGTGGTGTCCTGTGCAGCCGGTGTCACC ATCAGCTCCATTGAGAAGAAGCTGACGGCGTTCCAGCCAGCTCCCAAAGTCATCCGCTGC ATGACCAACACGCCGGTCGTGGTGCGGGAAGGGGCCACAGTGTATGCCACAGGCACCCAT GCCCAGGTGGAGGACGGCAGGCTCCTGGAGCAGCTCATGAGCAGCGTGGGCTTCTGCACG GAGGTGGAGGAGGACCTGATTGATGCCGTCACAGGGCTCAGTGGCAGTGGCCCAGCCTAT GCATTCACAGCCCTGGACGCACTGGCTGATGGAGGTGTGAAGATGGGACTTCCAAGACGC CTGGCAGTCCGCCTCGGGGCCCAGGCTCTGCTGGGGGCTGCCAAGATGCTACTGGACTCT GAACAGCACCCAGGCCAACTCAAGGACAACGTCTGCTCACCAGGCGGGGCCACGATCCAT GCGTTGCACGTGCTGGAGAGTGGGGGCTTTCGCTCGCTGCTCATCAAGGCCGTGGAGGCC TCCTGCACCCGCACACGAGAGCTGCAGTCCATGGCCGACCAGGAGAAGGTCTCACCAGCT GCCATCAAGAAAACCATCCTGGACAAGGTGAAACTGGACTCCCCTCCCGGCACCTCGCTG GCCCCTTCTGGCCACTCCAAGCTGCTGCCCCGCAGCATGGCCCCAGCAGGCAAACAGGAC TGA 320 33454.0 7.97 None >Pyrroline-5-carboxylate reductase 1, mitochondrial MSVGFIGAGQLAFALAKGFTAAGVVAAHKIMASSPDMDLATVSALRKMGVNLTHHNKETV QHSDVLFLAVKPHIIPFILDEIAANIEARHIVVSCAAGVTISSIEKKLTAFQPAPKVIRC MTNTPVVVREGATVYATGTHAQVEDGRLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAY AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLDSEQHPGQLKDNVCSPGGATIH ALHVLESGGFRSLLIKAVEASCTRTRELQSMADQEKVSPAAIKKTILDKVKLDSPPGTSL APSGHSKLLPRSMAPAGKQD AAX46360.1 Q58DT4 P5CR1_BOVIN BT021513 PYCR1