| Identification |
|---|
| BMDB Protein ID
| BMDBP01030 |
| Secondary Accession Numbers
| None |
| Name
| 17-beta-hydroxysteroid dehydrogenase 14 |
| Synonyms
|
Not Available
|
| Gene Name
| HSD17B14 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro) (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 18 |
| Locus
| Not Available |
| SNPs
| HSD17B14 |
| Gene Sequence
|
>813 bp
ATGGCAATGGGAACGCGCTATGCTGGGAAGGTGGTCATCGTGACCGGCGGCGGCCGCGGC
ATAGGAGCCGGGATCGTTCGAGCTTTCGTGGAAAGCGGTGCACAAGTGGTTATCTGTGAC
AAAGATGAGGCCAGGGGCAGGGCGGTGGAGCGAGAGCTTCCTGGCACTGTCTTTCTGCTC
TGTGACGTGACTCGGGAGGAAGATGTGAGGACCCTCGTTTCTGAGACCATCCGCCGTTTT
GGCCGCCTGGATTGCATAGTCAACAACGCTGGCTACCACCCACCCCCACAGTGGCCCGAG
GAGACCTCCGCCCAGGGCTTTCGCCAGCTGCTGGAGCTGAACCTGCTGGGGACATACACC
CTGACCAAGCTCGCCCTCCCTCACCTGCGCAAGAGCCGGGGAAATGTCATCAACATCTCC
AGCCTGGTTGGGGCGATTGGCCAGTCCCAAGCGGTTCCCTACGTGGCCACCAAGGGGGCA
GTGACAGCAATGACCAAAGCCTTGGCCCTGGATGAGAGTCAGTATGGCGTCCGTGTCAAC
TGCATCTCCCCTGGAAACATCTGGACCCCTCTGTGGGAAGAGCTGGCGGCCTCAACACCT
GACCCCACTGCTACAATCCGAGAGGGCACTCTGGCCCAGCCCCTGGGCCGCATGGGCCAG
CCAGCTGAGGTGGCGGCTGCTGCTGTGTTCTTGGCCTCCGAAGCCACCTTCTGCACGGGG
ACTGAGCTGCTCGTGACCGGGGGTGCGGAGCTGGGGTATGGGCGCAAGGCAGGCCAGGCC
GCCCCGGCGGAGGCCCCCACCACCCCTTCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 270 |
| Molecular Weight
| 28421.0 |
| Theoretical pI
| 6.52 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>17-beta-hydroxysteroid dehydrogenase 14
MAMGTRYAGKVVIVTGGGRGIGAGIVRAFVESGAQVVICDKDEARGRAVERELPGTVFLL
CDVTREEDVRTLVSETIRRFGRLDCIVNNAGYHPPPQWPEETSAQGFRQLLELNLLGTYT
LTKLALPHLRKSRGNVINISSLVGAIGQSQAVPYVATKGAVTAMTKALALDESQYGVRVN
CISPGNIWTPLWEELAASTPDPTATIREGTLAQPLGRMGQPAEVAAAAVFLASEATFCTG
TELLVTGGAELGYGRKAGQAAPAEAPTTPS
|
| External Links |
|---|
| GenBank ID Protein
| AAF62401.1 |
| UniProtKB/Swiss-Prot ID
| Q9MYP6 |
| UniProtKB/Swiss-Prot Entry Name
| DHB14_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF202997 |
| GeneCard ID
| HSD17B14 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
