1.0 2018-05-07 22:25:12 UTC 2020-05-20 21:06:17 UTC BMDBP01049 Enzyme ADAMTS2 Involved in metalloendopeptidase activity Cleaves the propeptides of type I and II collagen prior to fibril assembly (PubMed:7622483). Does not act on type III collagen (PubMed:7622483). Cleaves lysyl oxidase LOX at a site downstream of its propeptide cleavage site to produce a short LOX form with reduced collagen-binding activity (By similarity). BMDB0001303 Zinc 7 >3618 bp ATGGATCCGCCGGCGGGAGCCGCCGGCCGCCTGCTCTGCCCCGCGCTGTTGCTGCTCCTG CTGCTGCCGCTGCCCGCGGACGCCCGGCTCGCCGCCGCTGCCGCCGACCCCCCAGGCGGG CCCCAGGGGCACGGAGCCGAGCGCATCCTGGCGGTGCCGGTGCGCACTGACGCCCAGGGC CGCTTGGTGTCCCACGTGGTGTCGGCGGCGACGGCCCCAGCTGGGGTGCGGACCCGCAGG GCCGCCCCTGCCCAGATCCCGGGGCTCTCTGGAGGCAGCGAGGAGGACCCCGGTGGCCGC CTCTTCTACAATGTTACGGTGTTTGGCCGAGACCTGCACCTGCGGCTGCGGCCCAACGCC CGCCTCGTGGCGCCTGGGGCCACGGTGGAGTGGCAGGGAGAATCGGGTGCCACCCGCGTG GAGCCCCTGCTTGGGACCTGCCTCTACGTCGGAGACGTCGCGGGCCTGGCTGAATCCTCT TCCGTGGCGCTCAGCAACTGCGATGGGCTGGCTGGCCTGATCCGTATGGAAGAGGAGGAA TTCTTTATTGAGCCCCTGGAGAAAGGTCTGGCGGCGAAGGAGGCCGAACAGGGCCGTGTA CACGTGGTGTATCATCGACCGACCACCTCCAGACCCCCTCCTCTGGGGGGGCCACAGGCC CTGGACACAGGGATCTCCGCAGACAGCCTGGACAGCCTCAGCCGTGCTCTGGGTGTTCTG GAGGAGCGAGTCAACAGCTCCAGGCGGAGGATGCGCAGGCATGCTGCCGACGACGACTAC AACATCGAGGTCCTGCTTGGGGTGGACGACTCTGTGGTCCAGTTCCACGGGACGGAGCAC GTGCAGAAGTACCTGCTCACCCTCATGAACATTGTCAACGAAATCTATCACGATGAGTCC TTGGGGGCCCACATCAATGTCGTCCTGGTGCGGATAATCCTGCTGAGCTACGGGAAGTCC ATGAGTCTCATTGAGATTGGGAACCCCTCTCAAAGTCTGGAGAATGTTTGCCGCTGGGCC TACCTCCAGCAGAAGCCAGACACTGATCACGACGAGTACCACGATCACGCCATATTCCTC ACACGGCAGGACTTCGGGCCCTCGGGCATGCAAGGCTATGCTCCTGTCACTGGGATGTGC CACCCCGTCCGCAGCTGCACGCTGAACCACGAGGACGGCTTCTCCTCTGCGTTCGTGGTG GCCCACGAGACTGGCCATGTGCTGGGCATGGAGCATGATGGGCAGGGCAACCGCTGCGGT GACGAGGTGCGGCTGGGCAGCATCATGGCGCCCCTGGTGCAGGCAGCCTTCCATCGCTTC CACTGGTCCCGCTGCAGCCAGCAGGAGCTGAGCCGCTACCTGCACTCCTATGACTGCCTG CGGGATGACCCCTTCACCCACGACTGGCCGGCGCTGCCCCAGCTCCCCGGGCTGCACTAC TCCATGAACGAGCAGTGCCGTTTCGACTTTGGCCTTGGTTACATGATGTGTACCGCGTTC CGGACCTTCGACCCGTGCAAACAGCTGTGGTGCAGCCACCCTGACAACCCCTACTTTTGC AAGACAAAGAAGGGGCCACCCCTGGATGGGACCATGTGTGCGCCTGGCAAGCACTGCTTT AAAGGACACTGCATCTGGCTGACACCTGACATTCTCAAACGAGATGGCAACTGGGGTGCC TGGAGTCCCTTCGGCTCCTGCTCGCGTACCTGCGGCACAGGTGTGAAGTTCAGGACCCGT CAGTGCGACAACCCACACCCAGCCAATGGGGGCCGCACATGCTCGGGCCTCGCCTACGAT TTCCAGCTCTGCAACTCGCAGGACTGCCCTGACGCGCTGGCCGACTTCCGCGAGGAGCAG TGCCGGCAGTGGGACCTGTACTTCGAGCATGGTGACGCTCAACACCACTGGCTGCCCCAC GAGCACCGGGACGCCAAGGAGCGGTGTCATCTCTACTGTGAGTCCAAGGAGACCGGGGAG GTGGTGTCCATGAAGCGTATGGTGCATGACGGGACACGCTGTTCCTACAAGGACGCCTTC AGCCTCTGCGTGCGTGGGGACTGCAGGAAGGTGGGCTGTGACGGGGTGATCGGCTCCAGC AAGCAGGAGGACAAGTGTGGTGTGTGCGGAGGGGACAACTCCCACTGCAAGGTGGTCAAG GGCACGTTCTCGCGCTCGCCCAAGAAGCTTGGTTACATCAAGATGTTTGAGATCCCGGCA GGAGCCAGACACCTGCTAATCCAGGAAGCAGACACCACCAGCCATCACCTGGCCGTCAAA AACCTGGAGACAGGCAAGTTCATTTTAAATGAGGAGAATGACGTGGATCCCAACTCCAAG ACCTTCATCGCCATGGGCGTGGAGTGGGAGTACCGGGATGAGGACGGCCGGGAGACGCTG CAGACCATGGGCCCCCTCCACGGCACCATCACTGTGCTGGTCATCCCAGAGGGGGACGCC CGCATCTCACTGACCTACAAGTACATGATCCATGAGGACTCGCTCAATGTGGATGACAAC AACGTCCTGGAAGACGACTCTGTGGGCTATGAGTGGGCCCTGAAGAAGTGGTCGCCCTGC TCCAAGCCCTGCGGTGGAGGGTCCCAATTCACCAAGTATGGCTGCCGCCGGAGGCTGGAC CACAAGATGGTGCACCGAGGCTTCTGCGACTCCGTCTCAAAGCCCAAAGCCATCCGCCGG ACCTGCAACCCACAGGAGTGCTCCCAGCCCGTGTGGGTCACGGGTGAGTGGGAGCCGTGC AGCCGGAGCTGTGGGCGGACAGGCATGCAGGTTCGCTCTGTGCGCTGTGTTCAGCCTCTG CACAACAACACCACCCGCTCCGTGCACACCAAGCACTGCAATGACGCTCGACCCGAGGGC CGCCGGGCCTGCAACCGCGAGCTGTGCCCTGGCCGGTGGCGGGCTGGATCCTGGTCCCAG TGCTCAGTAACCTGTGGAAACGGCACCCAGGAACGGCCAGTGCTCTGCCGAACTGCGGAC GACAGTTTCGGGGTGTGCCGGGAGGAGCGGCCTGAGACGGCAAGGATCTGCAGGCTTGGC CCCTGTCCCCGAAACACCTCTGACCCCTCCAAGAAGAGCTACGTGGTCCAGTGGCTATCC CGACCGGACCCCAACTCGCCAGTCCAGGAGACCTCGTCAAAGGGCCGCTGCCAAGGTGAC AAGTCAGTGTTCTGTAGGATGGAAGTCTTGTCTCGTTATTGCTCCATCCCAGGCTACAAT AAGCTGTGCTGCAAGTCCTGTAACCCGCACGACAACCTCACTGATGTGGACGACAGGGCA GAGCCACCCTCTGGGAAGCACAATGACATTGAAGAGCTCATGCCCACCCTTTCAGTGCCC ACTCTAGTCATGGAGGTGCAGCCTCCGCCAGGCATACCCCTGGAGGTGCCTCTCAATACT TCCAGCACCAATGCCACCGAGGACCATCCAGAAACCAATGCTGTGGATGTGCCCTACAAA ATCCCTGGCCTGGAAGATGAAGTCCAGCCACCCAACCTGATCCCTCGACGACCGAGCCCA TATGAAAAGACCAGAAACCAAAGAATCCAAGAGCTCATTGATGAGATGAGGAAGAAAGAG ATGCTCGGAAAGTTCTAA 1205 133888.0 6.8 1-28 >A disintegrin and metalloproteinase with thrombospondin motifs 2 MDPPAGAAGRLLCPALLLLLLLPLPADARLAAAAADPPGGPQGHGAERILAVPVRTDAQG RLVSHVVSAATAPAGVRTRRAAPAQIPGLSGGSEEDPGGRLFYNVTVFGRDLHLRLRPNA RLVAPGATVEWQGESGATRVEPLLGTCLYVGDVAGLAESSSVALSNCDGLAGLIRMEEEE FFIEPLEKGLAAKEAEQGRVHVVYHRPTTSRPPPLGGPQALDTGISADSLDSLSRALGVL EERVNSSRRRMRRHAADDDYNIEVLLGVDDSVVQFHGTEHVQKYLLTLMNIVNEIYHDES LGAHINVVLVRIILLSYGKSMSLIEIGNPSQSLENVCRWAYLQQKPDTDHDEYHDHAIFL TRQDFGPSGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCG DEVRLGSIMAPLVQAAFHRFHWSRCSQQELSRYLHSYDCLRDDPFTHDWPALPQLPGLHY SMNEQCRFDFGLGYMMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTMCAPGKHCF KGHCIWLTPDILKRDGNWGAWSPFGSCSRTCGTGVKFRTRQCDNPHPANGGRTCSGLAYD FQLCNSQDCPDALADFREEQCRQWDLYFEHGDAQHHWLPHEHRDAKERCHLYCESKETGE VVSMKRMVHDGTRCSYKDAFSLCVRGDCRKVGCDGVIGSSKQEDKCGVCGGDNSHCKVVK GTFSRSPKKLGYIKMFEIPAGARHLLIQEADTTSHHLAVKNLETGKFILNEENDVDPNSK TFIAMGVEWEYRDEDGRETLQTMGPLHGTITVLVIPEGDARISLTYKYMIHEDSLNVDDN NVLEDDSVGYEWALKKWSPCSKPCGGGSQFTKYGCRRRLDHKMVHRGFCDSVSKPKAIRR TCNPQECSQPVWVTGEWEPCSRSCGRTGMQVRSVRCVQPLHNNTTRSVHTKHCNDARPEG RRACNRELCPGRWRAGSWSQCSVTCGNGTQERPVLCRTADDSFGVCREERPETARICRLG PCPRNTSDPSKKSYVVQWLSRPDPNSPVQETSSKGRCQGDKSVFCRMEVLSRYCSIPGYN KLCCKSCNPHDNLTDVDDRAEPPSGKHNDIEELMPTLSVPTLVMEVQPPPGIPLEVPLNT SSTNATEDHPETNAVDVPYKIPGLEDEVQPPNLIPRRPSPYEKTRNQRIQELIDEMRKKE MLGKF CAA65253.1 P79331 ATS2_BOVIN X96389 ADAMTS2